Haliaeetus albicilla (white-tailed eagle): 104319619
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Entry
104319619 CDS
T08398
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
hald
Haliaeetus albicilla (white-tailed eagle)
Pathway
hald00270
Cysteine and methionine metabolism
hald00480
Glutathione metabolism
hald01100
Metabolic pathways
hald01240
Biosynthesis of cofactors
hald04216
Ferroptosis
Module
hald_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
hald00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
104319619 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
104319619 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
104319619 (GCLC)
Enzymes [BR:
hald01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
104319619 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
104319619
NCBI-ProteinID:
XP_009919737
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All DBs
Position
Unknown
AA seq
584 aa
AA seq
DB search
MLVKFDHENKKVRLVLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVQDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPEYKPTPVEGGASKSL
FFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAK
PDYIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSD
IDCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDK
DIYEHLIKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFK
PPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKM
AQKRDAVRQGMFYFRKDICKGGNTVVDGCGSAQNGTGTDAEEYTLMSIDTIINGKEGVFP
GLIPILNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSV
ITDEMNYSLIWKCNQIAQGQAECPELLGVGFNKKQSGNKTGSLE
NT seq
1755 nt
NT seq
+upstream
nt +downstream
nt
atgttagtaaaatttgaccatgagaataagaaagtgcgcttggtgctctgcggtgaagaa
gttcttcaaacactgcaagacaagggggagaaggtaaaccccaaccacccaacactctgg
cgaccagaatatggaagctacatgatagaagggacgcctgggcagccgtatgggggaacc
atgtctgaattcaacaccgtgcaagacaacatgagaaaaagacggcaagaggcagcttct
gtcctcaaagaaaatgaggctgtttgtactgtgacgtcatttccaaggttagggtgtcct
gggtttacgctgccggaatataagccaacgccagtagaaggaggagcttcaaaatcactt
ttttttccagatgaagccatcaataaacatcctagatttagtacactgaccagaaacatt
cggcaccgaagaggagagaaggttgtgataaatgtaccaatatttaaagataagaacacg
ccatcaccgtttatcgaaacgtttcccaatgatgatggagaagcagcaaaggcggctaag
ccagactatatatacatggatgctatggggtttggaatgggaaactgctgtcttcaggta
acattccaggcttgcagcatttccgaagcgaggtatctctatgatcagctagccacgatc
tgtcccattgtgatggcattgagcgctgcatctccgttctacagaggctacgtgtctgat
attgactgtcgttggggagtgatctctgcatctgtagatgatcgaacgcgagaagagagg
gggctagagccactgaagaacaaccattatagaatcagtaaatccagatatgattccata
gacagttatctatctgaatgtggtgagaaatacaatgacattgatttgacaatagacaaa
gatatctacgagcacctaataaaggaaggtattgaccaccttttggcacagcatattgca
cacttgttcattcgagacccattgactttgtttgaggagaaaatacatctagatgatgca
aatgaatccgaccattttgagaatattcagtctacaaactggcagacaatgaggtttaag
ccaccacctccaaattcagatattggatggagagtggaattcagacctatggaggtccag
ttaacagactttgaaaactctgcatatgttgtgttcgtggtactgctaaccagagtgatt
ctgtcatataaactggattttctcattcctttgtccaaggtggatgaaaacatgaagatg
gcccagaaaagagatgctgtccggcagggaatgttttacttcagaaaagatatttgcaaa
ggtggaaacactgttgtggatggatgtggctctgcacagaatgggacaggcaccgacgcg
gaagagtacaccttaatgagtattgatacaattatcaatgggaaggaaggagtctttcct
ggtttgatcccaattttgaattcctatcttgaaaacatggaagtggatgtggacacaagg
tgcaccatcctaaactacctgaagctaataaaaaagagagcatctggagaattaatgaca
gttgctcggtggatgagggaatttatcgcacagcatccagactacaagcaagatagcgtg
ataactgatgaaatgaattatagccttatttggaaatgcaaccaaatcgcacaaggccag
gcagagtgtcctgaactgttgggggtaggatttaacaagaaacaaagtggaaacaaaact
ggctctttggaatga
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