Halorarum halophilum: HUG10_00340
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Entry
HUG10_00340 CDS
T06682
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
halg
Halorarum halophilum
Pathway
halg00290
Valine, leucine and isoleucine biosynthesis
halg00660
C5-Branched dibasic acid metabolism
halg01100
Metabolic pathways
halg01110
Biosynthesis of secondary metabolites
halg01210
2-Oxocarboxylic acid metabolism
halg01230
Biosynthesis of amino acids
Module
halg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
halg_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
halg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HUG10_00340 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HUG10_00340 (leuC)
Enzymes [BR:
halg01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HUG10_00340 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
HUG10_00340 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
QLG26082
UniProt:
A0A7D5KKE3
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Position
complement(60994..62421)
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AA seq
475 aa
AA seq
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MSEGTLYDKVWDRHKVTTLPTGQDQLFVGLHLIHEVTSPQAFGMLREREMEVAYPKLTYA
TVDHIVPTADQSRPYGDDAAERMMSELEENVRDAGIEFADPSTGDQGIVHVVGPEQGLTQ
PGKTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATGCVAMEKSDVRRIEVTGELGDGVE
AKDVILQIIRKLGTDGGVGYVYEYGGDAVESLGMEGRMSICNMSIEGGARAGYVNPDETT
FEWLGDTEAFRDDPDEFERLKPYWESVASDGDAEYDDVVTIDGDALEPMVTWGTTPGQGV
GISEPIPAPEDLPADKQDTARRAQDHMRVEPGETMQGYQVDVAFLGSCTNARLPDLRRGA
QVVRGREVHEDVRALVVPGSQHVQRAAEEEGLADTFREAGFEWRNAGCSMCLGMNEDQLE
GDEASASSSNRNFVGRQGSKDGRTVLMSPVMVAAAAVRGEVTDVRDLETLEEAEA
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgagcgagggaacgctgtacgacaaggtgtgggaccggcacaaggtgaccacgctcccg
accggccaggaccagctgttcgtcgggctccacctcatccacgaggtgacgagcccgcag
gcgttcggcatgctccgcgagcgcgagatggaggtcgcgtacccgaaactgacgtacgcg
accgtcgaccacatcgtcccgaccgcagaccagtcgcgcccctacggcgacgacgcggcc
gagcggatgatgagcgaactcgaggagaacgtccgcgacgcgggcatcgagttcgccgac
ccgtcgacgggcgaccagggcatcgtccacgtcgtcggtccggaacaggggctcacccag
ccgggcaagaccatcgtctgtggcgactcgcacacctcgacgcacggcgcgttcggcgcg
ctggcgttcgggatcggcacctcgcagatccgcgacgtgctcgcgaccggttgcgtcgcc
atggagaagagtgacgtgcgccggatcgaggtgaccggcgaactcggcgacggcgtcgag
gcgaaggacgtcatcctccagatcatccggaagctcggcaccgacggcggcgtcggctac
gtgtacgagtacggcggcgacgcagtcgagtcgttgggcatggagggccggatgtccatc
tgcaacatgtccatcgagggcggcgcccgcgcgggctacgtcaaccccgacgagaccacc
ttcgagtggctgggcgacaccgaggcgttccgcgacgacccggacgagttcgagcggctg
aagccgtactgggagtccgtcgcttccgacggggacgccgagtacgacgacgtcgtcacc
atcgacggcgacgcgctcgaaccgatggtgacctgggggacgacccccggccagggcgtc
ggcatctcggagccgatcccggcccccgaggacctccccgccgacaagcaggacacagca
cgccgggcgcaggaccacatgcgcgtggaacccggcgagacgatgcaggggtaccaggtg
gacgtggccttcctcggctcgtgtacgaacgcgcgcctgccggacctccggcggggggcg
caggtcgtccgcggccgggaggtccacgaggacgtccgcgcgctggtcgtccccggcagc
cagcacgtccagcgggccgccgaggaggaagggctcgccgacacgttccgcgaggccggc
ttcgagtggcgcaacgcgggctgctcgatgtgtctcggcatgaacgaggaccagctcgag
ggcgacgaggcctctgcgtcatcctcgaaccggaacttcgtcggccggcagggctcgaag
gacggcaggaccgtcctgatgagtcccgtgatggtcgcggccgcggccgtccgcggcgag
gtgaccgacgtccgcgacctcgagaccctcgaggaggcggaagcgtga
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