KEGG   Halodesulfurarchaeum formicicum HTSR1: HTSR_0382
Entry
HTSR_0382         CDS       T04517                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
halh  Halodesulfurarchaeum formicicum HTSR1
Pathway
halh00290  Valine, leucine and isoleucine biosynthesis
halh00660  C5-Branched dibasic acid metabolism
halh01100  Metabolic pathways
halh01110  Biosynthesis of secondary metabolites
halh01210  2-Oxocarboxylic acid metabolism
halh01230  Biosynthesis of amino acids
Module
halh_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
halh_M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:halh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    HTSR_0382 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    HTSR_0382 (leuC)
Enzymes [BR:halh01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     HTSR_0382 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     HTSR_0382 (leuC)
SSDB
Motif
Pfam: Aconitase
Other DBs
NCBI-ProteinID: AOW79582
UniProt: A0A1D8S2J3
LinkDB
Position
complement(366491..367897)
AA seq 468 aa
MSEGTLYDHVWNEHLVETLPTGQDQLFVGLHLIHEVTSPQAFGMLRERDLDVAFPERTHA
TVDHVIPTKDRSRPLEDEAAEEMLSALETNTSEAGITYSGPETGDQGIAHVVGPEQGLTQ
PGMTIVCGDSHTATHGAFGALAFGIGTSQIRDVLATGSVAAEKHDVRRIEITGELSEAAT
VKDLVLGLIRELGTDGGVGYVYEYGGPVVEAMSMEERMTLANMSIEGGATAGYINPDETT
YEYLQGRDAVPEGEAFEERKAYWESIRSNPDAIYDDVVEFDASQIEPSVTWGITPGQVVG
VTEPIPAPANLPAGQRDAAERAYEHMDVSPGETMDGYGVDVVFLGSCTNGRLPDLRAAAE
VLEGHEVDPDVEALAVPGSQRVKAAAEAEGLDEIFREAGFEWRDAGCSMCLGMNGDRLED
GQVSASSTNRNFVGRQGSKDGRTILMSPEMVAAAATEGEVTDVRTLDQ
NT seq 1407 nt   +upstreamnt  +downstreamnt
atgagtgagggcaccctgtacgaccacgtctggaacgagcacctggtcgagaccctgccg
acgggccaggaccagttgttcgtcgggctgcacctgatccacgaggtcacgagcccccag
gcgttcgggatgctccgggagcgggacctggacgtcgcgttccccgagcgaactcacgcg
accgtcgatcacgtcatcccgacgaaggatcggtcgcgaccgctcgaagacgaggccgca
gaggagatgctctcggccctggagacgaacaccagtgaggccggtatcacctactccggc
cccgagacgggtgatcaggggatcgcccacgtggtcggtccggagcaggggctcacccag
cccggcatgaccatcgtctgtggcgacagtcacaccgccacccacggggccttcggcgcg
ctggccttcgggatcgggacgagccagatccgggacgtcctcgcgactggctcggtcgcc
gcggagaaacacgacgtccggcgcatcgagatcacgggcgagttgagcgaggccgcgacg
gtcaaggacctcgtactcgggcttatccgcgaactcggcacggacggcggcgtgggctac
gtctatgagtacggcggccccgtcgtcgaggccatgtccatggaggagcgaatgaccctc
gcgaacatgtccatcgagggcggtgcgactgcggggtacatcaaccccgacgagaccacc
tacgagtacctgcagggccgcgacgcggtccccgagggcgaggccttcgaggagcgaaag
gcctactgggagtcgatccggtcgaaccccgatgcgatctacgacgacgtcgtcgagttc
gacgcctcccagatcgagccgtctgtcacctgggggatcaccccggggcaggtcgtcggc
gtcaccgagccgattccggccccggcgaatcttccggccggccagcgagatgccgccgag
cgagcctacgagcacatggacgtctcgccgggcgaaaccatggacggctacggcgtcgac
gtggtcttcctcggttcctgtacgaacggccggttgcccgacctgcgggctgccgccgaa
gtcctcgagggccacgaggtcgacccggacgtagaggccctggccgtgccagggagccag
cgggtcaaggccgccgccgaggcggaggggctcgacgaaatcttccgcgaggccggcttc
gagtggcgtgacgcgggctgttcgatgtgtctggggatgaacggcgaccgcctggaggat
ggccaggtttcggcctcctcgacgaatcgcaacttcgtcggtcgccagggcagcaaggac
ggccggacgatcctgatgagtcccgagatggtcgccgccgcggcgaccgaaggcgaagtg
accgacgtgcgaaccctcgaccaatga

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