Halomonas sp. MCCC 1A13316: HNO52_04095
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Entry
HNO52_04095 CDS
T10913
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
hamc Halomonas sp. MCCC 1A13316
Pathway
hamc00230
Purine metabolism
hamc01100
Metabolic pathways
hamc01110
Biosynthesis of secondary metabolites
Module
hamc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
Enzymes [BR:
hamc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
HNO52_04095 (purL)
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NCBI-ProteinID:
QOR37782
UniProt:
A0A7M1Q6Q7
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Position
864687..868628
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AA seq
1313 aa
AA seq
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MLELRGAPALSAFRHDKLLAALRARVPEVESLRAAYVHFVDHSGEFSDEERNLLGQLLDY
GIRSGSDEPQSALDSEGQLFLVVPRIGTQSPWSSKATDIAHNCGLERVRRIERGIAYRVA
LKAPMSEAAFMAIHETLHDRMTESVLTDASDAARLFAHHEPAPLGQVDILEGGRAALEEA
NLNLGLALAEDEIDYLVDAFRDLERNPSDVELMMFAQANSEHCRHKIFNADWVIDGEAQS
HSLFKMIKNTYQAAPENILSAYSDNAAVIEGTTAPRFFAAPLTGKAAERAVYAAQREPIH
ILMKVETHNHPTAIAPYPGAATGAGGEIRDEGATGIGGKPKAGLTGFTVSNLRIPEFVQP
WEAFDYGKPERMQSALAIMLEGPIGGASFNNEFGRPNLAGYFRTYEQDTMGAGGIERRGY
HKPIMIAGGYGNIREGHVQKGVIPVGGKLIVMGGPAMLIGLGGGAASSMASGASSADLDF
ASVQRENPEMERRAQEVIDRCWALGEANPIRFFHDVGAGGLSNALPELVKDGERGGRFEL
REVPNAEPGMSPLEIWCNEAQERYVLAVAPQDLDTFDALCARERCPYAVVGEATEAHHLE
VHDGHFATKPVDLPMSVLFGKPPKMQREFQREALELPGVMLDNLDLREAMERVLRLPTVA
SKSFLITIGDRSITGMVARDQMVGPWQVPVADVAVTTASFDTHAGEAMAMGERPPVALID
PAASARLAVAETITNLAAAPIENLGDIKLSANWMSAADHVGENQALFDAVHAVGMELCPQ
LGIAIPVGKDSMSMRTAWRSDDEAEEKSVTAPLTLAVTGFAPATDALKTLTPQINLDQDE
SDLILVDLGGGRNRLGGSALAQVYGQVGNECPDLDDPEDLKAFFAVIQGLNRDDKLLAYH
DRSDGGLLVTLLEMAFAARAGLEIKLDWLIDEPTQAVDALFAEELGAVIQVNRRHTEEVL
AQFAAAGIETCGVIARPRYDDQVRVTLFEEPLLETTRLLTQRTWAETSYRMQALRDNPDC
AKSEFDGLLDGRDPGLSATATFDVDEDIAAPFVNTSRPAVAILREQGVNGHVEMAWAFDR
AGFEAVDVHMSDILEGRITLEEFKGLVACGGFSYGDVLGAGGGWAKSVLFNPRAREQFAA
FFERDDSFGLGVCNGCQMFAQLKELIPGAENWPRFVRNESEQFEARVAMVQVEQNPSILL
AGMEGSRLPIAVAHGEGRAEFRDSAHLRSMQGSAQVALRYVDNYGQVTTHYPANPNGSPS
GITGLTTPDGRVTIMMPHPERVVRAVSNSWRPAEWGRDGAWMRLFRNARVWLG
NT seq
3942 nt
NT seq
+upstream
nt +downstream
nt
atgctcgaacttcgaggcgcgcctgccctttccgctttccgtcatgacaagctgctggct
gccctgcgcgcacgggttcccgaggtcgagtccctgcgcgccgcctacgtgcatttcgtg
gatcactccggtgaattttccgacgaggagcgtaacctcctcggccagttgctcgattat
ggcatcagaagcgggagcgatgagccccagagcgcgctcgatagcgaaggccaactgttc
ctcgtggtgccgcgcatcggtactcagtcgccatggtcgtccaaggccaccgacatcgcc
cacaactgcggcctggagcgagtgcgtcggatcgagcgcgggatcgcctaccgcgtggca
ctcaaagcgccgatgtccgaggcggccttcatggcgattcacgagaccctccatgaccgc
atgaccgagagcgtgctgaccgacgcctcagatgccgctcgattgttcgctcatcatgag
ccggcgccgctggggcaggtggatatcctcgaggggggccgtgcggcgctcgaggaagcc
aacctcaacctgggcctggcgctggccgaggatgagatcgactacctggtcgatgccttc
cgcgacctggagcgcaacccctcggacgtcgaactgatgatgttcgcccaggccaactcc
gagcattgccgacacaagatcttcaacgccgactgggtgatcgacggcgaggcgcagagc
cattcgctgttcaagatgatcaagaatacctaccaggccgcacccgagaacattctctcc
gcctatagcgataacgccgcggtgatcgaagggactacggcgccgcgtttcttcgccgcg
ccgctgaccggcaaggccgccgagcgcgccgtgtacgctgcgcagcgcgagccgatccac
atcctgatgaaggtggagactcacaaccaccccacggcgattgcgccctatccgggagca
gccaccggcgctggtggcgagatccgcgacgaaggtgccaccggcatcggcggtaagccc
aaggccggcctcaccggcttcaccgtctccaacctgcgcatccccgagttcgttcaaccc
tgggaggcgttcgactacggcaagcccgagcgcatgcagtcggcgcttgcaatcatgctt
gaggggcccatcggcggggcgtcgttcaacaacgaattcgggcgccccaaccttgccggc
tatttccgtacctatgagcaggacaccatgggggctggtggcatcgagcggcgcggctac
cacaagccgatcatgatcgccggcggctacggcaacattcgtgaaggccatgtgcagaag
ggcgtgatccccgtcggcggtaagctgatcgtgatgggcgggccggccatgttgatcggc
ctgggtggcggggcggcctcgtcgatggcctccggcgcctccagcgccgacctcgatttc
gcctcggtgcagcgcgagaaccccgaaatggaacgccgagcccaggaagtgatcgaccgc
tgctgggcgctgggcgaggccaatcccatccgcttcttccatgacgtcggtgccggcggg
ctctccaacgccctgcccgagctggtcaaggacggtgagcgcggcggacgcttcgagctg
cgcgaggtacccaacgccgagcccggcatgagcccgctggagatctggtgcaacgaggcc
caggaacgctatgtgctggccgtggcgccgcaggacctcgacaccttcgatgcgctgtgc
gcccgcgagcgctgcccctacgccgtggtcggcgaggccaccgaggcgcatcacttggag
gtgcacgacggtcacttcgcgacgaaaccggtcgacctgccgatgagcgtcctgttcggc
aagccgccgaagatgcagcgtgaatttcagcgcgaggcgctggaactgcccggcgtaatg
ctcgacaacctcgacctgcgcgaggcgatggagcgtgtgctgcgcctgcccacggtggct
tccaagagtttcctgatcaccattggcgaccgctcgattaccggaatggtggcccgcgac
cagatggtcggcccgtggcaggtgccggtggccgacgtcgccgtcaccaccgcgagcttc
gatacccacgccggcgaggccatggccatgggcgagcgcccgccggtggcattgatcgac
ccggcggcgagcgcccggctggcggtggcagagaccatcaccaacctagcggcggcaccc
atcgagaatctcggcgacatcaagctctccgccaactggatgagtgccgccgatcacgtc
ggcgagaaccaggcgctgttcgacgcggtccacgcggtgggcatggaactctgcccgcag
ctcggcattgccatcccggtgggcaaggactccatgtccatgcgcaccgcctggcggagc
gacgacgaggccgaggagaagagcgtcaccgcgccgctcacgttggcggtcactggcttc
gcgccggccaccgatgcgctgaagaccctgacgccgcagatcaacctcgaccaggacgag
agcgacctgatcctggttgacctgggtggcggccggaaccgcctgggcggctcggcactg
gcgcaggtctacggccaggtcggcaacgagtgcccggacctcgatgacccggaggatctc
aaggcgttcttcgccgtaatccaggggctcaaccgcgacgacaaactgctggcctaccac
gatcgcagcgacggtggcctgctggtgactctgctggagatggccttcgccgctcgcgcc
ggcctcgagatcaagctcgactggctgatcgacgagccgacccaggcggtcgatgcgctg
ttcgccgaggagctcggcgcggtgattcaggtcaaccgccggcataccgaagaggtgctg
gcccagttcgccgcggccggcatcgagacctgtggcgtcatcgctcggccacgctacgac
gaccaggtgcgcgtgaccctgttcgaggaaccgctgctggagaccacccggctgctgact
cagcgcacctgggccgagaccagctaccgcatgcaggcgctgcgcgacaatcccgactgc
gccaagagcgagttcgacggactgctcgacggccgcgatccgggcctctcggccactgcc
accttcgatgtcgacgaggacatcgccgcgccgttcgtcaacacgtcgcgtccggcggtg
gccatcctgcgcgagcagggcgtcaacggtcatgtggaaatggcctgggccttcgaccgt
gccggcttcgaggcggtggatgtgcacatgagcgacattctcgaagggcgaattaccctt
gaggagttcaagggtttggtcgcctgcggcggcttctcctacggcgacgtgctcggcgcc
ggcggcggctgggccaagtcggtgctgttcaacccgcgtgcccgggagcagttcgcagcc
tttttcgagcgcgacgacagcttcggtctcggggtgtgcaacggttgccagatgttcgcc
cagctcaaggaactgatccccggtgccgagaactggccgcgcttcgtgcgcaacgagtcc
gagcagttcgaggcccgggtggccatggtacaggtggagcagaatccttcgatcctgctg
gccggcatggaggggtcgcggctaccgatcgccgtggcacacggcgaggggcgtgccgag
ttccgcgacagcgcccacctgcgcagcatgcagggcagcgcacaggtcgcattgcgctac
gtcgacaactacggccaggtgaccactcactatccggccaaccccaacggctcgccttcc
ggcatcaccggcctgaccacaccggatgggcgtgtcaccatcatgatgcctcacccggag
cgggtggtgcgggccgtgagcaactcctggcgtcctgcggagtggggtcgggacggtgcc
tggatgcggctgttccgcaacgcgcgcgtgtggcttggctga
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