Halomonas sp. MCCC 1A13316: HNO52_08550
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Entry
HNO52_08550 CDS
T10913
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
hamc Halomonas sp. MCCC 1A13316
Pathway
hamc00280
Valine, leucine and isoleucine degradation
hamc00640
Propanoate metabolism
hamc00785
Lipoic acid metabolism
hamc01100
Metabolic pathways
hamc01110
Biosynthesis of secondary metabolites
hamc01210
2-Oxocarboxylic acid metabolism
Module
hamc_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hamc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
HNO52_08550 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
HNO52_08550 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HNO52_08550 (pdhA)
Enzymes [BR:
hamc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
HNO52_08550 (pdhA)
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GFIT
Motif
Pfam:
E1_dh
Transketolase_C
Transket_pyr
TPP_enzyme_C
DXP_synthase_N
PFOR_II
Transketolase_N
Transketolase_C_1
Motif
Other DBs
NCBI-ProteinID:
QOR38554
UniProt:
A0A7M1QA86
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Position
1839790..1841799
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AA seq
669 aa
AA seq
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MSTPSIDKPRLSRSHLLDLLRQMLRIRRFEERCVELYTQEKIRGFLHVYIGEEAVGTGVM
YGLRPDDAVVCTYREHGHALLNRIPMDRVMAEMYGKQAGCSRGRGGSMHLFDAAARFFGG
NAIVGGGLPLAVGLALADKLAGRSRVTVCFFGDGAAAEGTFHEGLNLAALWQLPVLFVCE
NNLYAMGTALRYSHAQTEIHRKAEALGVPAECVDGMDIARVEAASARLLESIRAGEGPRF
LECRTYRFRAHSMFDPELYRDKAEVEEWRKRDPILRLSQWMQQSGILHEGELEALEGEIA
AEVEQAVAYAEAAEWEPEASRFEHVYRQASAAPIAPPAVEPEPVELSYREAFRLGLIEAL
EHDERAFLMGEDIGHYGGCYAVSRGLLERFGPERIRDTPLSENGFTGAGIGAALGGARPI
VEIMTVNFSLLAMDQIVNAAATLLHMSGGEFNVPLVIRMATGAGRQVAAQHSHSLENWYA
HVPGLKVLAPGCLEDARYMLWAALQDPNPVLIFEHVMLYNREGRLEPCPQGVDIERAAIR
RAGRDLSLITYGGSLPKTLEAAEALAEEGIEAEVVDLRVLRPLDTATLIESVSRTHRAVI
VDEGWKTGSLAGEISAILAEQAFWALDAPIERVCTDEIPIPYPRHLENAALPQVANILAA
ARKAIGATP
NT seq
2010 nt
NT seq
+upstream
nt +downstream
nt
atgagtacgccttcgatcgataaaccgcggctgtcccggtcgcatctgctcgacctgctg
cgccagatgctgcgcatccgccgtttcgaggagcgttgcgtggagctctacacgcaggaa
aagatccgcggcttcctgcatgtctatatcggcgaggaggccgtgggcaccggggtgatg
tacgggctccgacccgacgatgcggtggtatgcacctatcgtgaacatggccacgcgcta
ctcaaccgcatccccatggatcgggtgatggccgaaatgtacggcaagcaggccggctgc
agcagggggcgaggaggctcgatgcacctgttcgacgccgctgctcgcttcttcggtggc
aacgccatcgtcggcggtggcctgccgttggccgtgggcctggccctggcggacaagctc
gccgggcgcagccgggtcaccgtctgcttcttcggcgacggcgctgctgcggaaggcacc
ttccatgaggggctcaacctggcagcgctgtggcagctgccggtgctattcgtctgcgag
aacaacctgtacgccatgggtacggcgctgcgttactcccatgcccagacggagattcac
cgcaaggccgaggcgctgggcgtgcctgcagaatgcgtcgatgggatggatatcgcccgg
gtggaggccgccagtgcccggctgctggaatcaatccgtgccggcgaagggccgcgcttc
ctcgagtgtcgcacctaccgttttcgcgcccactcgatgttcgatcctgaactttatcgc
gacaaggccgaggtggaggagtggaggaaacgcgatcccatactgcgcctgtcccagtgg
atgcagcaatcgggaatattgcacgagggtgaactcgaggcgcttgagggcgagatcgct
gcggaagtggaacaggccgtggcctacgccgaagcagcggagtgggagcctgaggccagc
cgattcgaacatgtctatcggcaagcgagcgccgcaccgatagcgccgcctgctgtcgag
cctgagcctgtggaactgagctatcgcgaggctttccggcttggcctgatcgaggcactg
gagcacgacgaacgtgctttccttatgggcgaggacatcgggcattacggcggctgctat
gcagtcagccgcggcctgctcgagcgcttcgggcccgagcgcatccgcgacacgccactg
tcggaaaatggcttcaccggtgccggcatcggcgcggcgctcggcggggcgcggcctatc
gtcgagatcatgacggtcaacttcagcctgctggccatggatcagatcgtcaacgccgcg
gccaccctgctgcacatgtccggcggcgagttcaatgtaccgctggtgatccgcatggcc
acgggagccggccgccaggtggccgcccagcactcccacagcctggaaaattggtacgcc
catgtaccgggtctcaaggtgctggcccccggctgtctggaggatgctcgctacatgcta
tgggcggcactgcaggatcccaacccggtgctgatcttcgagcacgtaatgctctataac
cgtgaagggcggctggagccctgcccacagggcgtggacatcgagcgtgccgccatccgc
cgagcgggtcgtgatctcagcctgatcacctacggaggcagcctgcccaagaccctggag
gcagccgaggccttggccgaggagggcatcgaggccgaggtggtggacctgcgcgtgctg
cgcccgctggacacggcgacgttgatcgagtccgtcagccgcacccatcgcgccgtgatc
gtcgatgagggctggaaaaccggcagcctggccggcgaaatctctgcgatcctcgccgaa
caagccttctgggcgttggatgcgcccatcgagcgggtctgcaccgacgaaatccccatc
ccctatccgaggcatctggaaaacgccgcgctgccgcaggtggcgaacatcctggccgca
gcacgcaaggccattggggcgacaccgtga
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