Hyperoodon ampullatus (northern bottlenose whale): 307052002
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Entry
307052002 CDS
T11951
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
hamp Hyperoodon ampullatus (northern bottlenose whale)
Pathway
hamp00230
Purine metabolism
hamp01100
Metabolic pathways
hamp04927
Cortisol synthesis and secretion
hamp04934
Cushing syndrome
hamp05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
hamp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
307052002 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
307052002 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
307052002 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
307052002 (PDE8B)
Enzymes [BR:
hamp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
307052002 (PDE8B)
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Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PDE8_3rd
PAS_4
PAS_8
JetB
Motif
Other DBs
NCBI-GeneID:
307052002
NCBI-ProteinID:
XP_079558821
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All DBs
Position
4:complement(<114703152..>114974958)
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AA seq
885 aa
AA seq
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MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPAAPLHGLFVQTDAADAIPPSRASW
PPGAARGRRARGELGSGSSAGSTAPAATTCRGRSRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDRRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASGNYEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDKNKQIHKVHRDSGDNSQTESHSFRHKNRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVPQSHSHLGMPVTI
NDVPPSITQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSETTLRAW
LQVIESNYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNILKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPIGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPTLMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggccccgcggcccccctg
cacggcctcttcgtccagaccgacgccgccgacgccatccccccgagccgcgcatcctgg
ccccccggtgccgcccgcggccgcagggcccgcggtgagctgggcagcggcagcagcgcg
ggctccacggcccccgcggcgaccacctgcaggggccggagtcgccactgctgcagcagc
gcggaggccgagacccagaccagctacaccagcgtcaagcaggtctcttcggcagaggta
cgcatcgggcccatgagactgacgcaggatcctatccaggttttgctgatctttgcaaag
gaagacagtcagagtgatggattctggtgggcctgtgacagagccggttacagatgtaat
attgctcggactccggagtcagccctggaatgctttctagataaacatcatgagattatt
gtgatcgaccgcagacaaactcgaaactttgatgcagaagcagtgtgcaggtcgatccgg
gccacaaatccctcggagcacacggtgattcttgcggtggtttcacaagcatccggcaac
tatgaagaggcctcggtcctccctcttctgcacgcaggcttcaaccggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcga
tcacagttcaagttaagggcctgtaattcagtgttcacagcattagaccactgtcacgaa
gccatagaaatcacaagcgatgaccacgtgattcagtatgtcaacccagccttcgaaagg
atgatgggctaccacaaaggtgagctcctggggaaagaactcgccgagctgcccaaaagt
gacaagaaccgggcggaccttcttgacaccatcaacacctgcatcaagaagggcaaggag
tggcagggggtttactatgccagacggaaatccggcgacagcatccaacagcatgtgaag
atcactccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactg
tgttgtaccactgacaaaaataagcagattcacaaggttcatcgtgactcaggagataat
tctcaaacagagtctcattcattcagacacaagaacaggaggaaagagtccattgatgtg
aaatcaatatcatctcgaggcagtgatgcaccaagcctacagaatcgtcgctatccatcc
atggcaaggatccattccatgaccatcgaggctcccatcacaaaggttataaatataatc
aatgcagcccaagaaaacagtcctgtcacagtagcagaagccttggacagagttttagaa
attttacggaccacagaactgtactcccctcagctgggtaccaaagatgaagatccccac
accagtgatctcgtgggaggcctgatgactgatggcttgagaaggttgtcaggaaacgag
tatgtgttcactaagaatgtgccccagagtcacagtcaccttgggatgccagtaaccatc
aacgatgtccccccttctatcactcaattacttgataatgaggaaagctgggagttcaac
atctttgaattggaagctgtgacacataaaaggccattggtttacctgggcttaaaagtc
ttttcccggtttggagtatgtgaatttttacactgttctgaaactacccttcgggcctgg
ctccaagtgattgaatccaactaccactcctccaatgcttaccacaactccactcatgcc
gctgatgtcctgcacgccactgccttcttcctcggaaaagaaagagtgaagggaagcctc
gatcagctagatgaggtggctgccctgattgctgccacagtccatgacgtggatcaccca
ggaaggaccaactctttcctgtgcaacgcaggcagtgaactcgccgtgctctataatgac
actgctgtcttggagagtcaccacacagccctggccttccagctcacggtcaaggacagc
aaatgcaacattctcaagaatattgacaggaaccattatcgaacactgcgccaggctatt
atcgatatggttttagcaacagagatgacaaaacactttgaacatgtgaacaaatttgtg
aacagcatcaacaagccaatggcagctgagattgaaggcagtgactgtgaatgcaaccct
attgggaagaactttcctgaaaatcaaatcctgattaagcgcatgatgattaagtgtgct
gacgtggccaatccatgccgccccctggacctatgtatcgaatgggccggaaggatctcc
gaggagtactttgcacagactgatgaagagaagagacaggggctacctgtagtgatgcca
gtgtttgaccggaatacctgtagcatccccaagtcccagatctcctttattgactacttc
ataacagacatgtttgatgcttgggatgcctttgcacacctgccaaccctgatgcaacat
ttggccgataactacaaacactggaagacgttagatgacctaaagtgcaaaagtctgagg
cttccatctgacagctaa
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