Hyperoodon ampullatus (northern bottlenose whale): 307053538
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Entry
307053538 CDS
T11951
Symbol
PDE5A
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform 1
KO
K13762
cGMP-specific 3',5'-cyclic phosphodiesterase [EC:
3.1.4.35
]
Organism
hamp Hyperoodon ampullatus (northern bottlenose whale)
Pathway
hamp00230
Purine metabolism
hamp01100
Metabolic pathways
hamp04022
cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:
hamp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
307053538 (PDE5A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
307053538 (PDE5A)
Enzymes [BR:
hamp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
307053538 (PDE5A)
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GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
HD-CE
DUF6970
Motif
Other DBs
NCBI-GeneID:
307053538
NCBI-ProteinID:
XP_079561110
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Position
1:<146386761..>146520759
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AA seq
865 aa
AA seq
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MERSGPNSARPQQQWDQDSVEAWLDDHWDFTFSYFVRKGTREMVNAWFAERVHTIPVCKE
GIRGHVESCSCPLQQSPCAESSVPGTPTRKISASEFDRPLRPIVVKDSEGTVSFLSDSEK
KKQMPLTPPRFDNDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSANDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAALGEPLNIKDAYEDPR
FNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCSDSFSSVFHMECEELEKSSDTLTRERDANRINYMYAQYVKNTMEPLNIPDVSKD
KRFPWTNENTGNVKQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEETTGKIKPFNRNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAMVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQNRLTDLEILALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIR
RRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPVQQRIAELVATEFFDQG
DRERKELNIEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTRVSEDCFPLLDGCRKNR
QKWQALAEQQEKTLINGESSQAKRN
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atggagcggagcggccccaactccgcgcggccgcagcagcagtgggaccaggactcggtc
gaagcgtggctggacgatcactgggactttaccttctcttactttgtcaggaaaggcacc
agagaaatggtcaatgcatggtttgctgagagagttcacaccatccctgtgtgcaaagaa
ggcatcagaggccacgtggagtcttgctcttgccccttgcagcagagtccctgtgcagag
agcagtgtccctggaacaccaaccaggaaaatctctgcctccgaatttgatcgacctctt
agacccatcgttgtcaaggattctgagggaactgtgagcttcctctctgactcagaaaag
aagaaacagatgcctctaacccccccacggtttgataatgatgaaggggaccagtgctcg
agactcttggaattagtgaaagatatttctagccacttggatgtcacagccttatgtcac
aaaattttcttgcatatccatggcctcatctccgctgaccgctattccctgttcctcgtc
tgtgaggacagcgccaacgacaagtttcttattagccgcctctttgacgttgcagaaggt
tcaacactggaagaagcttcaaataactgtatccgcttagagtggaataaaggcatcgtg
ggacacgtggcagctcttggtgagcccttgaacatcaaagatgcatatgaggatcctcgg
ttcaatgcagaagttgaccaaattacaggctacaagacacaaagtattctttgtatgcca
attaagaatcatagggaagaggttgttggtgtagcccaggccatcaacaagaaatcggga
aatggtgggacattcactgaaaaagatgaaaaggactttgctgcttacttggcattttgt
ggaattgttcttcataatgctcaactctatgagacttcactgctggagaacaagagaaat
caggtgctgcttgaccttgctagcctaatttttgaagaacaacaatcattagaagtaatt
ctaaagaaaatagctgccactattatctctttcatgcaggtgcagaaatgcaccattttc
atagtggatgaagattgctccgattctttttctagtgtgtttcacatggagtgtgaggaa
ttagaaaaatcgtcagatactttaacaagggaacgtgatgcgaacagaatcaattacatg
tatgctcagtatgtcaaaaatactatggaaccacttaatatcccagatgtcagtaaagat
aaaaggtttccctggacaaatgaaaacacaggaaatgtaaaacagcagtgcattagaagt
ttgctttgtacgcctataaaaaatggaaagaagaataaagtgataggggtttgccaactt
gttaataagatggaggagaccactggcaaaattaagcctttcaaccgaaatgatgaacag
tttctggaagcttttgtcatcttctgtggcttggggatccagaacacacagatgtacgaa
gcagtggagagagctatggccaagcagatggtcacattagaggttctgtcatatcatgct
tcagctgcagaggaagaaacaagagagctccaatccttagcggctgccatggtaccatct
gcccagacccttaaaatcaccgacttcagcttcagtgactttgagctatctgacctggaa
acggcactgtgcacaatccggatgttcactgacctcaaccttgtgcagaacttccagatg
aaacatgaggttctttgcaggtggattttaagtgttaagaagaactatcggaagaatgtc
gcctatcataattggagacatgcctttaatacagctcagtgcatgtttgctgcactaaaa
gcaggcaaaattcagaacaggctgactgacctggagatactcgcactgctgattgctgcc
ttaagccacgatttggatcaccgcggtgtgaataactcttacatacagcgaagtgaacac
ccacttgctcagctctactgccattcaatcatggagcatcatcattttgaccagtgcctg
atgatccttaatagtcctggcaatcagattctcagtggcctctccattgaagaatataag
accacgctgaaaataatcaagcaagctattttagccacagacctagcactgtacattagg
aggagaggagaattttttgaacttataagaaaaaatcaattcaacttggaagatcctcat
caaaaggaattgtttttagcgatgctgatgacagcttgtgatctttctgcaattacaaaa
ccctggcctgtccaacaacggatagcagaacttgttgccactgagttttttgaccaagga
gacagagagagaaaagaactcaacatagagcctgctgacctaatgaacagggagaagaaa
aacaaaatcccaagcatgcaagttggattcatagatgccatctgcttgcaactgtatgag
gccctgacccgcgtatcggaggactgtttccctttgctggatggctgcagaaagaacagg
caaaaatggcaggctcttgcagaacagcaggagaagacattgattaatggggaaagcagc
caggccaagcggaactga
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