KEGG   Hyperoodon ampullatus (northern bottlenose whale): 307054203
Entry
307054203         CDS       T11951                                 
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1
  KO
K02599  Notch 1
Organism
hamp  Hyperoodon ampullatus (northern bottlenose whale)
Pathway
hamp01522  Endocrine resistance
hamp04330  Notch signaling pathway
hamp04658  Th1 and Th2 cell differentiation
hamp04919  Thyroid hormone signaling pathway
hamp05020  Prion disease
hamp05165  Human papillomavirus infection
hamp05200  Pathways in cancer
hamp05206  MicroRNAs in cancer
hamp05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:hamp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    307054203 (NOTCH1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    307054203 (NOTCH1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    307054203 (NOTCH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    307054203 (NOTCH1)
   05206 MicroRNAs in cancer
    307054203 (NOTCH1)
  09162 Cancer: specific types
   05224 Breast cancer
    307054203 (NOTCH1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    307054203 (NOTCH1)
  09164 Neurodegenerative disease
   05020 Prion disease
    307054203 (NOTCH1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    307054203 (NOTCH1)
SSDB
Motif
Pfam: EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank Notch NOD NODP Ank_4 Ank_5 Ank_3 EGF_3 Gurken_M EGF_DL_JAG
Other DBs
NCBI-GeneID: 307054203
NCBI-ProteinID: XP_079561920
LinkDB
Position
6:<1422081..1467633
AA seq 2529 aa
MPPLLAPLLCLALLPALAARGLRCSQPGETCLNGGKCEVFPNGTEACVCSGAFAGQRCQA
PNPCLSAPCKNGGTCHTVERDGLVDYACRCRLGFSGPLCLTPRDHACLASPCLNGGTCDL
LTLTEYKCLCPPGWSGKTCQQADPCASNPCANGGQCLPFEASYICGCPPGFHGPTCRQDV
NECGQNPGLCHHGGTCHNEVGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDT
AHECACLPGFTGQNCEANIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQHCTEDVDEC
QLMPNACQNGGTCHNAHGGYNCVCVNGWTGEDCSENIDDCASASCFHGATCHDRVASFYC
ECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLG
ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICM
PGYEGVHCEVNTDECASSPCLQNGRCLDKINEFMCECPTGFTGHLCQYDVDECASTPCRN
GAKCLDGPNTYTCVCTEGYTGPHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHH
CETNINECHSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASNPCDSGTCLDKI
DGYECVCEPGYTGSMCHINIDECADDPCHNGGTCEDGVNGFTCRCPEGYHDPTCLSEVNE
CSSNPCIHGACRDSLNGYKCDCDPGWSGANCDINNNECESNPCVNGGSCKDMTSGYVCAC
REGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYAGATCEVVLAPCAPGPCR
NGGECKESKDYESFSCACPVGWQGQTCEIDINECVKSPCRAGASCQNTNGGYRCHCQAGY
TGRNCETDVDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASDPCRNGAN
CTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCLDGINSFTCLCPPGFTGSYCQ
HDVNECDSRPCLHGGTCHDSYGTYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGRCWQTNA
LYRCECHSGWTGLYCDVPSVSCEVAAWQQGINVTHLCRNGGLCVNVGNTHHCHCQAGYTG
SYCEDQVDECSPSPCQNGATCTDYPGGYSCECVAGYHGVNCSEEVNECLSQPCRNGGTCI
DLTNTYKCSCPRGTQGVHCEINVDDCNPPIDPVSRGPKCFNNGTCVDQVGGYSCTCPPGF
VGERCEGDVNECLSNPCDARGTQNCVQRINAFHCECRAGHTGRRCESVINGCKDRPCKNG
GSCAVASNTARGFICKCPAGFEGATCENDARSCGSLRCLNGGTCISGPRNPTCLCLGPFT
GPECQFPVSSPCMGGNPCYNQGSCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGVGLD
IPPPQIEEACELPGCREEAGNKVCSLQCNNHACGWDGGDCSLNFNDPWQNCTQSLQCWKY
FSNGRCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFRDGHCDQGCNSAECEWDGL
DCAEHVPERLAAGTLVLVVLMPPEQLRNHSLHFLRELSRLLHTNVVFKRDASGQQMIFPY
YGREEELHKHPIRRSVDGGASLLPGSGVGRRRRELDPMDIRGSIVYLEIDNRQCVQSSSQ
CFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPPPLHFMYVAVVAFVLLFFVG
CGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASDGALMDDNQN
EWGEEGLEAKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRVSAMAPTPPQGEADTDC
MDVNVRGPDGFTPLMIASCSGGGLETGKSEEEEDAPAVISDFIYQGASLHNQTDRTGETA
LHLAARYSRSDAAKRLLEAGADANIQDNMGRTPLHAAVAADAQGVFQILIRNRATDLDAR
MHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVEAAVVLLKNG
ANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVR
LLDEYSLVRSPPLHGAPTLSPPLCSPSGYLGNLKPAVQGKKARKPSTKGLACGGKEPKDL
KARRKKSQDGKGCLLDSSSVLSPVDSLESPHGYLSDVASPPLLPSPFQPSPSMPLNHLPG
MPDAHLGVSHLSVAAKPEMAALSGGGRLAFEAGPPRLSHLPVASGTSAVLGAGGSGSCGG
AVNFTVGGAAGLNGQCEWLSRLQNGLVPSQYNPLRGSVAPGTLSTQAPALQHGMVGPLHG
GLSATALSQMMSYQALPNTRLAAQPHLVQPQQQQQNLQMQPPNMQPQAPQPHLSVGSATS
GHMGRSFLAGELSQADVQPLGPGSLAAHTVLPQDSQVLPTSLPAALAPPMTTAQFLTPPS
QHSYSSPVDNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHSNISDWSEGISSPPTSMPSQ
IAHVPEAFK
NT seq 7590 nt   +upstreamnt  +downstreamnt
atgccgcctctcctggcgcccctgctctgcctggcgctgctgcccgcgctcgccgcacga
ggcctgcgatgttcccagcccggcgagacctgcttgaatggcgggaagtgtgaagtgttt
cccaacggcaccgaggcctgtgtctgcagtggagcctttgcgggccagcgatgccaggcg
cccaacccctgcctcagcgccccctgcaagaacggcgggacgtgccacacggtggagcgc
gacgggctggtggactacgcctgccgctgccgcctgggcttctcggggccgctgtgcctg
acgccccgcgaccatgcctgcctcgccagcccctgcctcaacggcggcacctgtgacctg
ctcactctcaccgagtacaagtgcctctgtcccccgggctggtcagggaagacatgccag
caggccgacccctgcgcctccaacccctgtgccaacggtggccagtgcctgcccttcgag
gcctcgtacatctgcggctgcccacccggcttccacggccccacctgcaggcaggacgtc
aacgagtgcggccagaaccccgggctctgccaccacggtggcacctgccacaatgaggtc
ggctcctaccgctgcgcctgccgtgccacccacaccggcccccactgcgagctgccctac
gtaccctgcagcccctccccctgccagaacgggggcacctgccgccccacaggggacacc
gcccatgagtgcgcctgccttccaggcttcaccggccagaactgcgaggcaaacattgac
gactgtccaggaaacaactgcaagaacggaggcgcctgtgtggacggcgtgaacacttac
aactgccgctgccccccggagtggacaggtcagcactgcaccgaggacgtggacgagtgc
cagctcatgcctaacgcctgccagaacggcgggacctgccacaacgcccacggcggctac
aactgcgtgtgtgtcaacggctggacgggcgaggactgcagtgagaacattgatgactgc
gccagtgcctcctgcttccacggcgccacctgccatgaccgcgtggcctccttctactgc
gagtgtccccacgggcgcacgggtctgctgtgccacctcaatgacgcctgcatcagcaac
ccctgcaatgagggctccaactgtgacaccaaccccgtcaacggcaaggccatctgcacc
tgcccctcgggctacacggggccggcctgcagccaggatgtggacgagtgctcgctgggc
gccaacccctgtgagcacgcgggcaagtgcatcaacacgctgggctccttcgagtgccag
tgtctgcagggctacaccggcccgcgctgcgagatcgacgtcaacgagtgtgtgtcgaac
ccatgtcagaacgacgccacctgcctggaccagattggggagttccagtgcatctgcatg
cccggctacgagggcgtgcactgcgaagtgaacacggacgagtgtgccagcagcccctgc
ctccagaatggccgctgcctggacaagatcaacgagttcatgtgcgagtgtcccacaggc
ttcactgggcacctgtgccagtacgacgtggacgagtgtgcaagcacgccctgcaggaat
ggcgccaaatgcctggacgggcccaacacctacacctgcgtgtgcacagaaggctacaca
gggccccactgtgaggtggacattgacgagtgcgaccccgacccctgccactatgggtcc
tgcaaggacggcgttgccaccttcacctgcctgtgccggccgggctacacgggccaccac
tgcgagaccaacatcaacgaatgccacagccagccctgccgccatgggggcacctgccag
gaccgcgacaatgcctacctctgcttctgcctcaaggggaccacaggacccaactgtgag
atcaacctggacgactgtgccagcaacccctgtgactcgggcacgtgtctggacaagatt
gacggctacgagtgtgtgtgtgagccgggctacaccgggagcatgtgccacatcaacatc
gatgagtgcgcggacgacccctgtcacaacggcggcacctgcgaggacggcgtcaacggc
ttcacctgccgttgccccgagggctaccacgaccccacctgcctgtccgaggtcaacgag
tgcagcagcaacccctgcatccacggggcctgccgggacagcctcaacgggtacaagtgt
gactgtgaccccgggtggagtggggcaaactgtgacatcaacaacaacgagtgtgagtca
aacccctgcgtcaacggcggctcctgcaaggacatgaccagcggctacgtgtgcgcctgc
cgggaaggcttcagtggccccaactgccagaccaacatcaacgagtgcgcgtccaaccca
tgtctgaaccagggcacgtgtatcgatgacgtggctgggtacaagtgcaactgcctcctg
ccctacgcaggagccacgtgcgaggtggtgctggccccatgtgccccaggcccctgcaga
aacggcggcgagtgcaaggagtccaaggactacgagagcttctcctgcgcctgcccagtg
ggctggcaggggcagacctgcgagattgacatcaacgagtgcgtgaagagcccgtgccgc
gcgggagcctcctgccagaacaccaatggtggctaccgctgccactgccaggccggctac
acagggcgtaactgcgagacggacgtcgacgactgccggcccaacccgtgccacaatggg
ggctcctgcacagacggcatcaacacggccttctgcgactgcctgcccggcttccagggc
gccttctgtgaggaggacatcaatgagtgcgccagcgacccctgccgcaatggcgccaac
tgcaccgactgcgtggacagctacacctgcacctgccccgcgggcttcagtgggatccac
tgtgagaacaacacgcctgactgcacggagagctcctgcttcaacggcggtacctgcctg
gacggcatcaactcctttacctgcctgtgcccgccaggcttcacgggcagctactgccag
cacgacgtcaatgagtgcgactctcggccctgcctgcacggtggcacctgccacgacagc
tatggcacctacaagtgcacctgcccacagggctacactggcctcaactgccagaacctc
gtgcgctggtgtgactcctcaccctgcaagaatggcggcaggtgctggcagaccaacgcc
ttgtaccgctgcgagtgccacagtggctggactggcctctactgtgacgtgcccagcgtc
tcctgtgaggtggccgcatggcagcaaggcatcaacgttacccacctgtgccggaacgga
gggctgtgcgtgaacgtgggcaacacgcaccactgccactgccaagcgggctacacgggc
agctactgcgaggaccaggtagacgagtgttcgcccagcccctgccagaacggggccacg
tgcaccgactaccctggtggctactcctgcgagtgtgtggctggctaccacggggtgaac
tgctccgaggaggtcaacgagtgtctgtcccagccgtgccggaacgggggcacctgcatc
gacctcaccaacacctacaagtgctcctgcccccggggcacacagggcgtgcactgcgag
atcaacgtggacgactgcaacccccccatcgatcccgtgtcccggggccccaagtgcttt
aacaacggcacctgcgtggaccaggtgggcggctacagctgcacctgcccgcccggcttc
gtgggcgagcgctgtgagggtgatgtcaacgagtgcctgtccaacccctgcgacgcccgc
ggcacccagaactgcgtgcagcgcatcaacgctttccactgcgagtgccgtgccggccac
accgggcgccgctgtgagtcggtcatcaacggctgcaaggacaggccctgcaagaacggg
ggcagctgtgccgtggcctccaacaccgcccgcgggttcatctgcaaatgcccagcgggc
ttcgagggtgccacgtgtgagaatgatgcacgcagctgcggcagcctgcgatgcctcaac
ggcggcacctgcatctcgggcccgcgcaaccccacctgcctgtgcctgggccccttcacc
ggccccgagtgccagttccctgtcagcagcccctgcatgggtggcaacccctgctacaac
cagggcagctgcgagcccacgtccgagagccccttctaccgctgtctgtgccccgccaag
ttcaacgggctcctgtgccacatcctggactacagcttcggcggtggcgtgggcctcgac
atccccccgccgcagatcgaggaggcctgcgagctccccggctgccgcgaggaggccggc
aacaaggtctgcagccttcagtgcaacaaccacgcctgcggctgggacggcggcgactgc
tccctcaacttcaacgacccctggcagaactgcactcagtccctgcagtgctggaagtac
ttcagcaacggccgctgcgacagccagtgcaactcggccggctgcctcttcgacggcttc
gattgccagcgcgcagaaggccagtgcaaccccctgtacgaccagtactgcaaggaccac
ttcagggacgggcactgcgaccagggctgcaacagcgccgagtgcgagtgggatgggctg
gactgcgcggagcacgtgcccgagcggctggcggccggcacgctggtgctggtggtgctg
atgccgcccgagcagctgcgcaaccactccctgcacttcctgcgcgagctcagccgcctg
ctgcacacgaacgtggtcttcaagcgtgatgccagcggccagcagatgatcttcccctac
tacggccgcgaggaggagctgcacaagcaccccatcaggcgctctgtggacggtggggcc
tcgctgctcccgggcagcggggtcgggcgccggcgcagggagctggacccgatggacatc
cgcgggtccatcgtctacctggagatcgacaaccggcagtgcgtccagtcgtcctcgcag
tgcttccagagcgccacggacgtggccgccttcctgggcgcgctcgcctcgctgggcagc
ctcaacatcccctacaagatcgaggccgtgcagagtgagacggtggagccgcccccgccc
ccgccgctgcacttcatgtacgtggccgtggtggccttcgtgctgctcttcttcgtgggc
tgtggggtgctgctgtcgcggaagcgccggcggcagcatggccagctctggttccccgag
ggcttcaaggtgtcggaggccagcaagaagaagcggcgggagcccctcggcgaggactcc
gtgggcctcaagcccctgaagaacgcctcggacggcgccctcatggacgacaaccagaac
gagtggggcgaggagggcctggaagccaagaagttccggttcgaggagcccgtggtcctt
cccgacctggatgaccagacagaccaccggcagtggacccagcagcacctggacgccgct
gacctccgcgtgtccgccatggctcccacgccgccccagggcgaggccgacaccgactgc
atggacgtcaatgtccgcgggccggacggcttcacgcccctcatgatagcctcctgcagt
ggagggggcctggagacgggcaagagcgaggaggaggaggacgcgcccgcggtcatctcg
gacttcatctaccagggcgccagcctgcacaaccagacggaccgcaccggcgagaccgcc
ctgcacctggctgcccgctactcgcgctccgacgcggccaagcgcctgctggaggccggc
gctgacgccaacatccaggacaacatgggacgcaccccgctgcacgcggccgtggctgcg
gacgcgcagggtgtctttcagatcctcatccggaaccgagccacggacctggatgcccgc
atgcacgacggcacaactccactgatcctggccgcccgcctggccgtcgagggcatgctg
gaggacctcatcaactcccacgccgatgtcaacgccgtggacgacctgggcaagtccgcc
ctgcactgggccgccgcggttaacaacgtggaggccgccgtcgtgctgctgaagaacggg
gccaacaaggacatgcagaacaacaaggaggagacgcccttgttcctggccgcccgggag
ggcagctacgagacggccaaggtgctgctggaccatttcgccaaccgggacatcacggac
cacatggaccgtctgccccgcgacatcgcgcaggagcgcatgcaccacgacatcgtgcgg
ctgctggacgagtacagcctggtgcgcagccccccgctgcacggcgcgcccaccctgtcg
cccccgctctgctctcccagcggctacctgggcaacctcaagcccgccgtgcagggcaag
aaggcccgcaagcccagcaccaagggcctggcctgcggcggcaaggagcccaaggacctc
aaggcacggaggaagaagtcccaggacggcaagggctgcctgctggacagctcgagcgtg
ctgtcgcccgtggactccctggagtccccccacggctacctgtcggatgtggcctccccg
cccctcctgccctcccctttccagccatctccctctatgcccctcaaccacctacccggg
atgcctgatgcccacctgggcgtcagccacctgagtgtggcggccaagcccgagatggca
gcgctgagtgggggtggccggctggcctttgaggcagggccgccacgcctctcccacctt
cccgtggcttctggcaccagcgcggtcctgggtgctggtggcagcgggagctgcggtggg
gccgtgaatttcaccgtgggtggggccgcaggcttgaacggccagtgcgagtggctgtcc
cggctgcagaatggcctggtgccgagccagtacaacccgctgcgagggagcgtggcgccg
ggcaccctgagcacgcaggcccctgccctccagcacggcatggtgggcccgctgcacgga
ggcctgtctgccaccgccctgtcccagatgatgagctaccaggccctgcccaacacgcgg
ctggccgcccagcctcacctggtgcagcctcagcagcaacagcagaacttacagatgcag
ccaccgaacatgcagccgcaggcaccgcagccacacctcagcgtgggctcggccaccagc
ggccacatgggccggagcttcctggcgggggagctgagccaggcggacgtgcagcccctg
ggccccggcagcctggcggcacacaccgtcctgccgcaggacagccaggtcctgcccacg
tcgctgccggccgcgctggccccgcccatgaccaccgcccagttcctgacgcccccctcc
cagcacagctactcctcccccgtggacaacacccccagccaccagctgcaggtgcccgag
caccccttcctcaccccgtccccggagtcccccgaccagtggtccagctcatcgccacac
tctaacatctccgactggtccgagggcatctccagcccgcccaccagcatgccgtcccag
atcgcccacgttcctgaggcctttaagtaa

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