Hyperoodon ampullatus (northern bottlenose whale): 307058631
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Entry
307058631 CDS
T11951
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform 1
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
hamp Hyperoodon ampullatus (northern bottlenose whale)
Pathway
hamp00270
Cysteine and methionine metabolism
hamp00480
Glutathione metabolism
hamp01100
Metabolic pathways
hamp01240
Biosynthesis of cofactors
hamp04216
Ferroptosis
Module
hamp_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
hamp00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
307058631 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
307058631 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
307058631 (GCLC)
Enzymes [BR:
hamp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
307058631 (GCLC)
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GFIT
Other DBs
NCBI-GeneID:
307058631
NCBI-ProteinID:
XP_079568296
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Position
10:<65267832..65305395
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETQRHADHVRLHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKYNHYRISKSRYDSIDSYLSECGEKYNDIDLTKDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGLFYFRKDICKGGNAMVDGRGKTTGSTEPAAEEYALMTIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LLLKCNQIANELCECPELLGPAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctactgtcccagggctcgccactgagctgggaggagacccagcgccacgccgac
cacgtgcggctgcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtatcttttgatcat
gaaaataaaaaagcccaactggtactgtctggagaggaacttcttgaaactctgcaagaa
aagggggaaaggacaaacccaaaccaccctaccctttggaggccagagtatgggagctac
atgatcgaggggacacctggccagccgtacggagggaccatgtctgagttcaacacggtc
gaggacaacatgaggaagcgccgcaaggaagcgacatctctactgggagaaaaccaggcc
ctctgcacgatcacttcgtttcccagattaggctgccctgggttcacgctgcccgagttc
aagcccaacccagtggaaggaggagcttccaagtccctcttctttcctgatgaagcgata
aacaagcacccgcgcttcagtaccctcaccaggaacatccggcacagaagaggagagaag
gttgtcatcaacgtcccaatatttaaggacaagaatacaccatctccatttatagaaaca
tttcctgaggatgatgaggcagcaaaggcttctaagcccgaccacatttacatggacgct
atgggctttgggatgggcaattgctgtctgcaggtaacgttccaagcctgcagcatatct
gaggccagatacctttatgatcagttggccactatctgcccaattgtcatggctttgagc
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggcgtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagtacaac
cactataggatcagtaagtcccgatacgattcaatagacagttacttatctgagtgcggt
gagaaatataatgacatcgacctgacgaaagacaaagaaatctatgaacagctgttgcag
gaaggcatcgatcatctcctggcccagcacgtggctcatctcttcattagagacccgctg
actctgtttgaagagaaaatccacctggacgatgccaatgagtccgaccattttgagaat
attcagtccacaaattggcagacaatgcgatttaagcctcctcctccaaactccgacatt
ggatggagagtggaattccggcccatggaggttcagttgacagacttcgagaactccgcg
tacgtggtgttcgtggtgctgctcaccagggtgatcctttcctacaaactggactttctc
atcccgctgtcaaaggttgatgagaacatgaaagtagcacagaagcgagatgccgtcctg
cagggattgttttatttcagaaaagatatttgcaaaggtggcaacgccatggtggacggc
cgcggcaagaccacgggcagcaccgagccagcagccgaggagtacgcgctcatgaccatc
gacaccatcatcaacggcaaggaaggtgtgttccccgggctgatccccatcctgaactct
tacctggaaaacatggaggtggatgtggacaccagatgcagtattctgaactacctgaag
ctgattaagaagagagcatccggagaattaatgacagttgccagatggatgagggagttc
atcgcaaaccatccagactacaagcaagacagtgtaataactgacgagatgaactatagc
cttcttttaaagtgtaaccaaatcgcaaatgaattgtgtgaatgcccagagttacttgga
ccagcatttaggaaagtaaagtacagtggaagtaaaactgactcttccaactag
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