| Entry |
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| Symbol |
Top2
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| Name |
(RefSeq) DNA topoisomerase 2-alpha
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| KO |
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| Organism |
hamr Hetaerina americana (American ruby spot damselfly)
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| Brite |
KEGG Orthology (KO) [BR:hamr00001]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:hamr03032]
139694417 (Top2)
03036 Chromosome and associated proteins [BR:hamr03036]
139694417 (Top2)
Enzymes [BR:hamr01000]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
139694417 (Top2)
DNA replication proteins [BR:hamr03032]
Eukaryotic type
DNA Topoisomerases
139694417 (Top2)
Chromosome and associated proteins [BR:hamr03036]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
139694417 (Top2)
Centrosome formation proteins
Centriole proteins
139694417 (Top2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1578 aa
MERPPGELAMINGDHGGDAEAKKPPPGKKLAVEKIYQKKSQLEHILIRPDTYIGSVLPVN
ELMWVYDQEENKMVQRNISYVPGLYKIFDEILVNAADNKQHDSTMDCIKIDIDAEKNFIS
VWNNGRGIPVVEHKEEKMYVPTMIFGHLLTSSNYNDEEAKLTGGRNGYGAKLCNIFSTKF
TVETASKEFKKYFKQTWYGNMGKASEVKLLDYHKEDFTRIAFSPDLQKFQMETLDKDIVS
LMSRRAFDVAASTRGVNVYLNGKKLPVKSFKDYVELYLKDKKDETGQSLKSIHEVVNDRW
EVAVTISDRGFQQVSFVNSIATTKGGRHVEYVVDMIVKQVSEILKKKNKIGIQVKSHQIK
NYMWIFVNCLIVNPAFDSQTKENMTLQSKNFGSKCKLSDKFFTAVSKLGIVESILRWAKY
KAENQLQTKCSGKKQNKLKGIAKLEDANDAGTRNSLDCTLILTEGDSAKTVAVTGLAVVG
RDKYGVFPLRGKLLNVREATHKQIIENQEINNIIKIMGLQYKKIYESVDDLKTLRYGRMM
IMTDQDQDGSHIKGLLINFIHHNWPSLLKLPFLEEFITPIVKATKGSTQLRFYSLPEFED
WKKDTGNWYSFKIKYYKGLGTSTAEEAREYFADMGRHRVLFKHGGPQDDHSIIMAFSKKC
VDQRKEWLTTWMEDTKRRRELGLTATFLYQTNTKVVTFSDFVNKELVLFSNLDNERSLPC
LVDGLKPGQRKVVFTCFKRNDKREIKVAQLAGSVAEHSAYHHGEVSLMSTIINLAQNFVG
SNNINILQPIGQFGSRLQGGKDAASPRYIFTMLSPLAKLIFHPHDEALLNYLQEDNQKIE
PEYYVPVIPMILVNGADGIGTGWMTKIPNYNPREIIANIKRLLDGEAPESMKPWYKNFRG
TVTDIAHQRALVCGEISMLGPTSFEITELPVGTWTQAYKETVLEPMLHGLAEKVPSLITD
YREYNSDTTVRFVVHMTEDKLVKAEEEGLHKVFKLQTIQNLTSMVCFDAMGCLRKYESVD
DILKEFFEVRLKFYEKRKSYLEGLLQTEVSKLSNQARFICEKCDGVLVIENKKKKAMIEE
LVKRGYDSDPVKSFKLKQNKDDVMQEIGESGELSQEEVDVDDELDFDYLLGMTMWSLTKE
RKDELLKKKEDKQQEYRILQATTPSQIWRTDLDNLLEMLDQVEAKELAVAQAGNTIVAKA
GKGKPVGKRKGGVMASETMPSPIGKKVVPRIGEELLKKVEKAVWAKENKGKRMPKVKKEK
EEEKDEFDAMCDGKTPTLAQRVGNSPEAVESKLKAKKAVKQTKLNFGKKSKKMDSDEDGG
PLNEEADVGAEEISPVAREVPKRAAAAKAKLSYDDDDDDAVVFSSDSEKWGGGQVSDAHI
SVSDSDSEFEVSKKKTTKSSQSKALRIQDTSDSLFDSLVGSSPEKLMAPPVPVAPAPSVP
VVSASVPVVSEPAPTSFSNGTNKRNFTDSSDEDSAPAKAPPKKKPAAPRAPKEPKEPKPK
AKPARKPAAKKRPMNSDSDEEFELTKPTKVKSKAKASADDDFMGSDVDEYAPPPPKTGGS
GRTRKPVKYALSSDDDSD |
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| NT seq |
4737 nt +upstreamnt +downstreamnt
atggagagacctcctggtgaattagcgatgataaacggtgatcatggaggagatgcggaa
gcgaaaaagccgcccccgggaaagaaactggcggtggaaaaaatataccagaagaaatcg
caacttgagcatattttaattagacctgatacctatattgggtctgtgttaccggtaaat
gaattaatgtgggtgtatgatcaggaagaaaataaaatggtgcagcgtaatatatcatat
gtacctgggctatacaagatttttgatgaaattcttgttaatgctgctgacaacaagcaa
catgattcaacaatggattgcattaaaatagatattgatgcggagaagaatttcatatcg
gtgtggaataatggaagaggaattcctgttgtggagcacaaagaggagaagatgtatgtt
cctacaatgatttttggccatctgttgacatcttcaaattacaatgatgaagaagcaaag
cttacaggaggtagaaacggttatggagcaaaactttgcaatatatttagtacaaaattc
acagtggaaactgcttctaaggagttcaagaaatattttaagcagacttggtatggcaat
atgggtaaggcctcggaagtgaagctgttagattatcacaaagaagattttactagaatt
gcattctcaccagatctacagaaatttcaaatggaaactctagataaagacatagttagc
ttaatgagccgacgtgcctttgatgtggctgcatccacacgtggagtgaatgtgtaccta
aatgggaaaaaacttcctgtaaaatccttcaaggattatgttgaactatatctgaaagat
aagaaagatgagacaggtcaatcactgaagtctatacatgaagttgtaaatgatcgatgg
gaggttgctgttacaatttcggatagaggcttccaacaagtttcatttgtgaacagtatt
gcaaccaccaagggtggccgtcatgtagaatatgttgtcgacatgatagtgaagcaggtg
agtgagatacttaagaagaagaataagatcggtattcaagtgaaatcgcatcaaataaag
aattacatgtggatttttgtcaactgcctcattgttaacccagcatttgactcacaaact
aaggaaaatatgactctgcagtccaaaaattttggctcaaagtgcaagctctctgacaag
ttctttactgctgtctctaaattaggaatcgttgaatccatcctcagatgggcaaaatac
aaggctgagaatcagcttcaaacgaaatgcagtggcaagaaacaaaataaattgaaagga
attgcaaagctggaggatgcgaatgatgcagggaccagaaattctcttgactgtacactc
attcttactgaaggagattcagccaaaactgtggctgtaactggacttgctgttgtagga
agagataaatatggtgtatttcctctaaggggtaaactactgaacgttcgtgaagctacc
cacaagcagattattgaaaatcaagaaattaacaacataatcaaaataatgggtcttcag
tacaaaaagatttatgaatcagttgatgatctgaagaccttgagatatggcagaatgatg
atcatgactgatcaggatcaggatggctcccacatcaagggacttcttattaactttatc
catcacaactggccatcactgttaaaactgccatttttggaggaattcatcactccaatc
gtcaaagctacgaagggctccactcagttacgtttctactcattacctgaatttgaggac
tggaagaaagacacagggaactggtatagcttcaagataaagtactacaaaggtttggga
acctctacagcagaggaagctagggaatattttgctgacatgggacggcatcgtgttctt
ttcaagcatggtggtccacaggatgatcattccatcatcatggccttcagcaagaagtgt
gttgatcagcgcaaggaatggctgaccacctggatggaggataccaaacgaaggcgagaa
ctaggccttacagccacgttcctctaccagactaacacaaaagtggtcaccttttcagat
tttgtgaacaaagagctggttcttttcagcaaccttgataatgaacgttccctaccttgt
ctggttgatggtttaaaacctggacaaagaaaggttgtctttacctgcttcaagcgaaat
gataaacgtgaaataaaagttgcacaattggcaggttcagtggctgaacactcagcctat
caccatggtgaagtttctcttatgtccacaatcattaatttggcccaaaactttgtcggt
agcaataatataaatattttgcagcctattggtcaatttggctccagattacagggtggc
aaagatgctgccagccctaggtatattttcaccatgctaagccccttggcaaagcttatc
ttccaccctcatgatgaagcactcctcaattacttgcaagaagacaatcagaaaatagag
cctgagtactatgttcctgtaataccaatgatattagtaaatggagctgatggaattggt
actggttggatgacaaaaattccaaactacaacccacgagaaataatagccaatatcaag
aggcttcttgatggggaagcacctgagagcatgaaaccttggtataagaatttccgtggc
acagtaactgatatagcccatcaacgtgcattggtttgtggtgaaatatcaatgcttggg
cctacctcctttgaaattacagaacttccagttggcacgtggacccaggcgtacaaggag
acagttttggagcccatgcttcatggtttggccgaaaaggttccttcgttgataactgac
tacagggagtataactctgacacaactgttaggtttgtggttcatatgactgaagataaa
ttagtaaaagcagaagaggagggcttacacaaggtgttcaaactgcagacgattcagaac
ctcacttccatggtttgctttgatgccatgggctgcttgagaaaatatgaatctgtggat
gatatcttgaaggaattctttgaagtgagactgaaattctatgaaaagagaaagagctat
ttggaaggactcctgcagacagaagtatctaaactctccaatcaggcaaggttcatctgc
gagaagtgtgatggtgttcttgtaattgaaaacaagaaaaagaaggcaatgattgaagaa
ctcgtgaaaagaggctatgattctgatcctgtgaaatccttcaagttgaagcagaataag
gatgatgtcatgcaagaaataggtgaatctggagagctgtcacaggaagaggtcgacgtt
gatgatgagttagattttgactatttgcttggaatgaccatgtggtctctcacaaaagaa
aggaaggatgagttgctgaaaaaaaaggaggataaacagcaggaatataggatcctacaa
gctaccacaccttctcagatttggcgaaccgatcttgataatttacttgaaatgctggat
caggtggaagcaaaggaattggccgtagctcaggctggcaatacaatagtggcaaaagca
ggaaagggcaaaccagttggcaaaaggaagggtggtgtaatggccagtgaaactatgccg
tcacccataggcaagaaagtagtcccacgaattggtgaggagctgctgaaaaaagttgag
aaagcggtgtgggcaaaggagaacaaagggaaaaggatgcctaaggtcaagaaggaaaag
gaggaagaaaaggatgagtttgatgcaatgtgtgatggaaaaactccgaccctggcacaa
agagtgggcaattcccctgaagctgttgagagcaagttaaaagctaagaaagctgtgaag
caaacaaaattgaacttcggcaagaagtctaaaaagatggactcggatgaagatggtggc
ccattaaatgaagaggctgatgtaggtgcggaagaaattagtcctgtcgctcgtgaagtt
cccaaacgagctgctgctgctaaggccaagttatcatatgatgatgatgatgatgatgca
gtagtatttagcagtgatagtgaaaagtggggtgggggccaagtttccgatgcacacatt
tctgtctctgactcagatagtgagtttgaagtttcaaagaagaagaccaccaagtcatct
cagtccaaagcactacgcatacaagatacctctgattccttattcgattcacttgtgggg
agtagtcctgagaaacttatggcaccacctgtacctgttgcaccagctccaagtgttcct
gtagtaagtgcaagtgttcctgtagtaagtgaacctgctcctacttcttttagcaatggg
accaacaagagaaattttacggattcctcagatgaagacagtgctccagccaaagctcct
cccaagaaaaaaccggctgctcctcgtgcaccgaaagagcccaaggaaccaaaaccaaag
gctaagccagcaagaaagccagctgccaagaaaagacccatgaattctgattccgatgaa
gaatttgagctgacaaagccgaccaaagtcaaaagtaaggcaaaagcgagtgctgatgat
gattttatgggcagtgatgtggatgagtatgctccaccacctccaaaaactggtggttct
ggccgtaccagaaagcctgtcaagtatgcactctcttctgacgacgattcagattga |
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