KEGG   Glaesserella parasuis SH0165: HAPS_1271
Entry
HAPS_1271         CDS       T00825                                 
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
  KO
K12524  bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
Organism
hap  Glaesserella parasuis SH0165
Pathway
hap00260  Glycine, serine and threonine metabolism
hap00261  Monobactam biosynthesis
hap00270  Cysteine and methionine metabolism
hap00300  Lysine biosynthesis
hap01100  Metabolic pathways
hap01110  Biosynthesis of secondary metabolites
hap01120  Microbial metabolism in diverse environments
hap01230  Biosynthesis of amino acids
Module
hap_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
hap_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:hap00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    HAPS_1271 (thrA)
   00270 Cysteine and methionine metabolism
    HAPS_1271 (thrA)
   00300 Lysine biosynthesis
    HAPS_1271 (thrA)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    HAPS_1271 (thrA)
Enzymes [BR:hap01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     HAPS_1271 (thrA)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     HAPS_1271 (thrA)
SSDB
Motif
Pfam: Homoserine_dh ACT_9 AA_kinase NAD_binding_3 ACT_7 ACT Sacchrp_dh_NADP DUF1131
Other DBs
NCBI-ProteinID: ACL32864
UniProt: B8F6B2
LinkDB
Position
1249562..1252006
AA seq 814 aa
MRVLKFGGTSLANPERFLQAADIIEKAHLADQAAGVLSAPAKITNHLVAIVDKAQTGESY
ESHLTEATDIFNNIINGLYAVNNNFDREGLSAFIKAELDDICNIAAEAAKNKFCPDNIGA
TVHSRGEKLSIAMMKAWFEAKGYEVTRIDPIEKLLAHGSYLESSVDIAESTKRIEALSIP
KKNVVLMAGFTAGNEQGELVLLGRNGSDYSAACLAACLKADVCEIWTDVDGVYTCDPRLV
PDAICLESMSYQEAMELSYFGAKVIHPRTIGPLVPLNIPCLIKNTHNPEAPGTIIDSNVV
NDNLKVKGITNLDNVAMFNVSGSGMQGMVGMAARVFTSMSQAGISVNLITQSSSEYSISF
CVPVKAVEKALCALNNTFAQELKDGSLDPVEVIKDLSIISVVGDGMRTAKGIAARFFSAL
AQANISIVAIAQGSSERSISAVVPLNKAIEAVKATHKALFNNKKVVDVFLVGVGGVGGEL
IEQITTQKEYLAKKDIEIRVCALANSNKMLLNENGLSLDNWRADLESATQPSDFDVLLSF
IKLHHVVNPVFVDCTTAQSVANLYSRALKEGFHVITPNKKANTSSYAYYQEMRENARQSQ
HKFLYETNVGAGLPVIENLQNLLAAGDEVEKFEGILSGSLSFIFGKLEEGSSLSEATTIA
KEKGFTEPDPRDDLSGQDVARKLLILARECGYPLELEDIEVEGVLPKGFSEGKTAAEFLA
MLPEIDVEFAKRVENATACGNVLRYVGSIENGKCRVAIKEVNGDDPLYKVKNGENALAFY
TRYYSPIPLLLRGYGAGNDVTAAGIFADILRTLN
NT seq 2445 nt   +upstreamnt  +downstreamnt
atgcgagttctaaaatttggaggtacttctttagccaatccagaacgctttttacaagcc
gctgacatcatcgaaaaggcacatttggcagaccaagccgcaggcgtactatccgcccca
gctaaaatcactaaccatcttgtcgctattgtcgataaagcccaaacaggcgaatcctac
gaatctcatctcaccgaagccaccgacattttcaataacatcatcaacggattatatgcc
gtcaataacaatttcgaccgtgaaggattaagtgcctttatcaaagcagaactagacgac
atctgcaatattgcagctgaagcagcaaaaaataaattctgcccagataatatcggtgca
acagtgcatagccgtggggaaaaattgtcgattgcgatgatgaaagcgtggtttgaagcg
aaaggttatgaagttactcgcattgatcctatcgaaaaattattagcacacgggagctat
ttagaatcttctgtggatattgctgaatcgaccaaacgtattgaagctctttctattcca
aagaaaaacgtcgtgttaatggcgggctttacggcaggtaacgaacaaggtgaattggtg
ttacttggtcgtaatggttcagactactctgctgcctgtttagccgcttgcttaaaagcg
gatgtgtgcgaaatttggacggatgtggatggtgtttatacttgcgatcctcgtttagta
ccagatgcgatctgtttagagtctatgagctatcaagaagcgatggagctttcttacttc
ggtgcgaaagtgatccaccctcgcactattggtccgttagtaccgttaaacattccatgc
ttaattaaaaatacccataatccagaagcaccaggcacaatcattgacagtaatgtagtc
aatgataatttaaaagtgaaagggatcacgaaccttgataatgtggcaatgttcaatgtt
tcaggctcaggtatgcaaggtatggttggtatggctgctcgtgtgtttacttcgatgtcg
caagcgggtatttccgtgaacttaattacacaatcttcttctgaatatagtattagtttc
tgtgtgcctgtaaaagcggtcgaaaaagcactctgtgcgttaaacaatacttttgctcaa
gagttaaaagatggctcgcttgatcctgtggaagtgatcaaagatctctcaattatttct
gtggttggtgacggtatgcgtaccgccaaagggattgcggctcgcttcttctctgcactg
gctcaagcaaatatcagcattgtggcgattgcacaaggttcatcagaacgttccatttct
gctgttgtgccgttaaataaagcgattgaagcggttaaagctacacataaagcgttattc
aataacaaaaaagtggtcgatgtctttttagtgggtgttggcggtgtgggtggcgaattg
atcgaacagatcacaacccagaaggaatatcttgcaaagaaggatattgagatccgtgtt
tgtgcattagctaactcaaataaaatgttgctcaacgaaaacggcttaagccttgataac
tggcgtgcggatttagagtcggcgacacagccatctgactttgatgtgttgctttcattc
attaaattacatcacgttgttaatcctgtttttgtcgattgcacgacagcacaatcggtg
gcaaatctttattctcgtgcattaaaagaaggcttccacgtaattacaccaaataagaaa
gcgaatacctcaagctatgcttattatcaggaaatgcgtgaaaatgctcgtcaaagccaa
cataaattcttatatgaaaccaatgtgggcgcaggcttgcctgtaatcgaaaacctacaa
aatttgcttgctgccggcgatgaagtcgagaaatttgaagggattttatctggttcgctt
tcttttattttcggtaaattagaagaaggttcaagtttgtctgaagcaaccaccattgct
aaagaaaaaggcttcacagaacctgatccacgtgatgatttatcagggcaagatgtggct
cgtaaattgctgattttagcccgtgaatgtggctatccattagagctggaagatattgaa
gtggaaggtgttttaccaaaaggtttctctgaaggcaaaactgcagcagaatttttagcg
atgttgccggagattgatgtggaatttgcaaaacgtgtggaaaacgcgaccgcttgtggc
aatgtgttgcgttatgtgggctccattgaaaacggtaaatgccgtgtcgcaatcaaagaa
gtaaacggtgatgatccactttataaagtgaaaaatggtgaaaatgcccttgcgttctat
acccgttattacagcccgatcccactgttactgcgtggctacggtgcgggtaatgatgtg
acggcagcgggtatttttgcggatattttgcgtacactgaattaa

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