Halanaerobium hydrogeniformans: Halsa_1608
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Entry
Halsa_1608 CDS
T01349
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
has
Halanaerobium hydrogeniformans
Pathway
has00300
Lysine biosynthesis
has00550
Peptidoglycan biosynthesis
has01100
Metabolic pathways
has01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
has00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Halsa_1608
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Halsa_1608
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Halsa_1608
Enzymes [BR:
has01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Halsa_1608
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PF1197-like_C
Motif
Other DBs
NCBI-ProteinID:
ADQ15033
UniProt:
E4RIG3
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All DBs
Position
complement(1792738..1794111)
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AA seq
457 aa
AA seq
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MESLTLAQIAEAASGKIIKGKAEIKIKDIVIDSREVKKDDLFIAIIGEINDGHEFIDSAV
ENGAKAVIVDRQINDYSNLAVIKVDDTTKALQDIAHYYRMKFKDLKIAAITGSVGKTSTK
DMIAAVLAQKYKTLKTSGNYNNQIGLPLTLLRLCSKDEFAVLEMGMSGFGEIELLAELAR
PQIAVITNVGPAHIEQLGSIENVAAAKKELLDSLDKSGTAILNYDNEYTRKMAENFNSKL
ITFGFSAGADLQVIENKFNKDLNREEFKIIWQGKKLKFYLNKPGKHNIYNALAAIAIGFL
NNMNPKGIQDGLSKIDFSDLRMEIKELENGAIVINDSYNANPISVRAALDVLAEMKGKRK
IAVLASMLELGKMEKKAHLEIGEYIAKQNIDLLITVGEIAELIAEGAERTAMPVEKIYSF
ADKASTLKFLKDNLKKDDLLLIKGSRSNQMEKIVAEL
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atggaaagtttaaccttagcccaaattgcagaagcggcttctggaaaaattattaaaggt
aaagcagaaatcaaaatcaaagatattgttattgacagcagagaggtaaaaaaagatgat
ttatttattgctattattggggaaataaatgatggtcacgaatttattgattcagctgta
gaaaatggagcaaaagcagttattgtagatcgtcaaattaatgattattcaaatcttgct
gttatcaaagttgatgatacaactaaagcattacaggatattgctcattattacagaatg
aagtttaaagatctaaaaattgctgcaataactggaagtgtaggtaaaacaagtacaaaa
gatatgatagctgcagttttagcccagaaatataaaactttaaaaacctcaggtaattat
aataatcaaattggtttacctttaactctactgcgactctgttctaaagatgagtttgca
gttttagaaatgggtatgagtggttttggagaaattgaactattagcagaattagcccgg
ccgcaaatagctgtgatcactaatgttggacctgctcatattgaacaactgggttcaatt
gaaaatgtggcagcagcaaaaaaagaacttcttgattctttggataaatctggtacagca
attttaaattatgataatgaatatacgagaaaaatggcagaaaattttaattcaaagcta
ataacttttggtttttctgcaggagcagatctgcaggtaatagaaaataaatttaataaa
gatttaaatagggaagaatttaagattatctggcagggaaaaaagcttaaattttattta
aataagcctggcaaacataatatatataatgctttagctgctattgctattggtttttta
aataatatgaatcctaaaggtattcaagatggcttaagtaaaatagatttttctgattta
agaatggagataaaagaattagaaaatggagcaattgtgattaacgatagctataatgct
aatcctatttcagttagggcagcgcttgatgttttagcagaaatgaaaggtaaacggaag
attgctgttttagcttcaatgcttgaattaggaaaaatggaaaaaaaggcccatttggaa
atcggtgaatatatagctaaacaaaatatagaccttttaatcacagttggggagattgca
gaattaatcgcagaaggagcagaaagaaccgcaatgcccgttgaaaaaatatattctttt
gctgataaagccagcactttaaaatttttaaaagataatttaaaaaaagatgatcttttg
cttattaaaggctcaagatctaatcaaatggaaaaaatagttgcagaactataa
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