KEGG   Halopseudomonas sp. SMJS2: QAO71_13490
Entry
QAO71_13490       CDS       T10383                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
hasm  Halopseudomonas sp. SMJS2
Pathway
hasm00290  Valine, leucine and isoleucine biosynthesis
hasm00620  Pyruvate metabolism
hasm01100  Metabolic pathways
hasm01110  Biosynthesis of secondary metabolites
hasm01210  2-Oxocarboxylic acid metabolism
hasm01230  Biosynthesis of amino acids
Module
hasm_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:hasm00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    QAO71_13490 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    QAO71_13490 (leuA)
Enzymes [BR:hasm01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     QAO71_13490 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: WGK61064
LinkDB
Position
2865025..2866695
AA seq 556 aa
MTMLTDPSSKYRPFTPIALPDRTWPDKVINQAPIWLSTDLRDGNQSLIEPMDAEKKMRFF
KCLVAIGVKEIEVGFPSASQTDFDFVRELIEGGHIPDDVTIQVLTQARDDLIERTFESVK
GAKQAIVHYYNACAPAFRKIVFNQDKAGVKAIAIAAGKTIRRLAEAAPETNWGFEYSPEV
FSSTETDFAVEVCNAVIGVFEPTPQRKLILNLPATIECATPNNYADQIEWFGRHIDRRDS
VLISVHTHNDRGTGVAASELAVMAGADRVEGCLFGNGERTGNVCLVTLALNLYTQGVDPQ
LDFSDIDAVRKVVEDCNQLPVHPRHPYAGDLVHTAFSGSHQDAIRKGFAQQDPNAVWEVP
YLPIDPADIGRSYEAVIRVNSQSGKGGITYLLEQEYGIALPRRLQIEFSQVVQGETDRLG
LEMTAEQIHQLLQREYLQATTPYALVRHRLQEENGTSAVDVEVINAGTTQHWRGIGKGPL
EALVAGLPEAVEIIDYHEHAIGSGSDAKAAAYIEVRLDNGRPLHGIGIDENLTAASFRAL
FSALNRAKQQAAAQAA
NT seq 1671 nt   +upstreamnt  +downstreamnt
atgaccatgctcaccgatccgtccagcaagtaccgtccgttcactcccatcgcgctgcct
gatcgcacctggccggacaaggtcatcaaccaggcaccgatctggctgtccaccgacctg
cgcgatggcaatcagtcgctgatcgaaccgatggatgcggaaaagaagatgcgctttttc
aagtgcctggtcgcgatcggcgtgaaggaaatcgaagtcggcttcccatccgcctcccag
accgatttcgacttcgtgcgcgagttgatcgagggcgggcatattcccgatgacgtcacc
atccaggtactgacccaggcccgtgacgatctgatcgagcggacgttcgagtcggtcaaa
ggcgccaagcaggccatcgtgcactactacaatgcctgtgcccccgccttccgcaagatt
gttttcaatcaggacaaagccggggtgaaagccattgccatcgccgcgggcaaaaccatc
cggcgcctggctgaagccgcgccggaaaccaactggggcttcgagtactcccctgaggtg
ttcagctcgaccgagaccgattttgccgtcgaggtatgcaacgccgtgattggcgtgttc
gagccgaccccacagcgcaagctgatcctcaacctgcccgcgactatcgaatgcgctacg
ccgaacaactatgccgaccagatcgagtggttcggtcggcatatcgaccggcgtgacagc
gtgctgatcagcgtgcatacccacaatgatcgcggcactggcgttgccgcctcggagttg
gcggtaatggccggcgctgatcgcgtcgaaggttgcctgttcggcaacggcgaacgcacc
ggcaacgtctgcctggtcaccctggcgctgaacctctatacccagggcgtcgatccgcag
ctggacttttccgatatcgacgcggtacgcaaggtagtcgaggattgcaatcagttgccg
gttcacccgcgccacccctatgccggcgacctggtgcacaccgccttctccggctcgcac
caggatgcgatccgcaagggcttcgcccagcaggacccgaacgccgtctgggaagtaccc
tacctgccgatcgacccggcggatatcggtcgcagctacgaggcggtgatccgcgtcaac
agccagtccggcaaaggcggcatcacctacctgctggagcaggagtatggaatcgccctg
ccgcggcgcttgcagatcgagttcagccaggtggtacaaggtgaaaccgatcgcctcggt
ctggaaatgaccgccgagcagatccaccaactgctgcagcgcgaatatctgcaggccacc
accccctatgccctggttcgccaccggctgcaggaagagaatggcaccagcgcggtggat
gtcgaggtaatcaacgctggcactacccagcattggcgcggcattggcaaaggcccgctg
gaggcattggtcgccggcctgccggaagccgtggagatcatcgactaccatgaacatgcc
atcggctcgggcagcgatgccaaggcagcagcgtatatcgaggtccgcctggataatggc
cgccccttgcacggtattggcatcgatgaaaacctgactgcggccagtttccgggcgctg
ttcagcgcattgaaccgggccaagcaacaggccgcagcccaggccgcctga

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