Hirschia baltica: Hbal_0389
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Entry
Hbal_0389 CDS
T00945
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hba
Hirschia baltica
Pathway
hba00300
Lysine biosynthesis
hba00550
Peptidoglycan biosynthesis
hba01100
Metabolic pathways
hba01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hba00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Hbal_0389
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Hbal_0389
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Hbal_0389
Enzymes [BR:
hba01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Hbal_0389
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACT58091
UniProt:
C6XME8
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Position
415874..417310
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AA seq
478 aa
AA seq
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MNKSLWTSKEIAAATKGEMTGDWKVSGISIDSREVAKGDLFVALKDLRDGHEYVSSAIEK
GAAGALISSDCGDVPCVTVDNTLHALENLGLAARARSKAIHAAITGSVGKTSVKEMIAQI
FRSKGKAHWNVKSFNNHFGVPLTLARMPRDTKRAIFEIGMNTPGEIAPRSRMVRPQIALV
TKIAGAHLEGMGTIEAVADEKSDIFCGLEPNGVAILPREDDFFDYMKARVFDCQPTASLL
SFGGAQSEADARLISFEPEGNGSQGTADILGETVSFQLNAIGDHWGMNAVLAILVGRLSG
MSAQEAADGLKGYTPPAGRGAAEILKMPFGEITLLDDSYNANPESMRAGLAALGQRSGRK
IAILGEMRELGPDADKLHADLKDPILKAGVSELFLAGDGLLPLRDSCSNNENEPGVCWAS
TSKELVLMVNKSLISGDVVLIKGSNASGIASVANALKALSQGPEERNEKMSAAITGGE
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
gtgaataaatctctctggacctcaaaagaaatagctgcagccacaaaaggcgagatgaca
ggagactggaaagtatccggtatttccattgatagccgagaagttgcaaaaggtgatttg
tttgttgcgctgaaagatctgcgtgacggacatgaatatgtgtcttccgccatcgaaaaa
ggtgctgccggggcgttgatctctagcgattgtggcgatgtgccatgtgtgaccgtagat
aacacgctgcacgcgttggaaaatcttggtctagctgcacgtgcgcgctcaaaagccatc
catgctgctatcactggttcggtgggtaaaaccagcgtgaaagaaatgatcgcgcaaatt
ttccgctccaaaggaaaagcgcattggaatgtgaaatcattcaataatcactttggcgtg
ccgcttaccttggcgcggatgccgcgcgatacaaaacgcgctattttcgagattgggatg
aacacgccgggagagattgcgcctcggtctagaatggtgcgcccgcagatagcgttggta
actaaaattgccggtgctcaccttgagggtatgggaacgattgaagccgttgctgacgaa
aaatcagatattttttgtggccttgagcctaatggtgtcgccattctgccgcgtgaagat
gatttttttgattatatgaaggcacgtgtctttgattgccagccgacagcctcgcttttg
tcttttggtggtgctcaaagtgaagctgatgcgcgcttgataagttttgaaccagaggga
aatggctcgcaaggcactgcagacattctgggcgagactgtttctttccagctaaatgca
attggtgatcattggggcatgaatgcagttcttgctattttggttggtcgcctctctggt
atgtctgcccaagaagcggcagacggtctgaaaggttatacaccgccagctggtcgcggt
gcggctgaaatactgaaaatgccatttggcgaaattacgctgctcgatgattcctataat
gcaaacccagaaagcatgcgcgctggtcttgctgcattggggcagcgttccggtcgtaaa
atagcaatcctcggagagatgcgagaactggggccggacgcggataaattacacgcagat
ttgaaagatcctatcctcaaagcgggtgtttcagagctctttttggcaggtgatggatta
ttaccattgcgtgacagttgcagtaataatgagaacgaaccgggggtttgctgggcgtca
acctcaaaagaactagttttaatggttaataagtcgttaataagtggtgatgtcgtcttg
ataaaaggctcgaatgcatccggtatagcgagtgtcgcaaatgccctgaaagcactcagc
caagggcctgaagagagaaacgaaaaaatgtcagctgcaatcacaggaggcgagtaa
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