Helicobacter pylori PeCan18: HPPC18_03635
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Entry
HPPC18_03635 CDS
T02036
Name
(GenBank) D-alanyl-D-alanine-adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hca
Helicobacter pylori PeCan18
Pathway
hca00300
Lysine biosynthesis
hca00550
Peptidoglycan biosynthesis
hca01100
Metabolic pathways
hca01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hca00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HPPC18_03635
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HPPC18_03635
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HPPC18_03635
Enzymes [BR:
hca01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HPPC18_03635
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AFI02480
UniProt:
I0EHR1
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All DBs
Position
761150..762631
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AA seq
493 aa
AA seq
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MQSLSWLNLAFRWLFITGLGYYMMTLLQWYHYSVFRILTKHHKMRWHGIYFLLPLGVFIL
SYAFKMPFVFDFFCSVIQMPMLIIWAKRNDKPLVFTPRVKRFFIFLLLFLILHEILNTEL
APLNGISLALGYLCLFILVLSASLIFEKVLSKQYLQTAKDKIASLKNLKVIAITGSFGKT
STKNFLHQILQTQFNAHASPKSVNTLLGIANDINQNLDDRSEIYIAEAGARNKGDIKEIT
RLIEPHLAVIAEVGEQHLEYFKTLENICETKAELLDSKRLEKAFCYSVEKIKPYAPKDSP
LTDVSSLVRNVQSTLKGTSFEMLIDSVWESFETKVLGEFSAYNIASAILVAKHLGLETER
IKRLVFELKPINHRLQLLEVNQKIIIDDSFNGNLKGMLEGIRLASLHQGRKVIVTPGLVE
SNTESNEALAQKIDGVFDVAIITGELNSKTIASQLKTPQKILLKDKAQLENILQATTIQG
DLILFANDAPNYI
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcaaagtcttagttggctgaatttagcgtttcgttggctctttataacagggcttggc
tattacatgatgactttattgcaatggtatcattacagcgtgtttaggattttaaccaaa
caccacaagatgcgttggcatgggatttatttccttttacctttaggggtgtttatccta
tcgtatgctttcaaaatgccgtttgtttttgattttttttgcagcgtgattcaaatgccc
atgctcattatctgggccaaacgcaacgacaagcctttagttttcacgccaagggtgaag
cgcttttttattttcttattactctttttaatcttgcatgaaatcttaaacacagaatta
gcccctttgaatgggatttcgctcgcgctgggctatttgtgcttgttcatactcgtttta
agcgcttctttaatctttgaaaaagtcctatccaagcagtatttgcaaaccgctaaagat
aaaatcgcctctttaaaaaatttaaaagtcatcgccattaccggaagctttgggaaaacc
agcaccaaaaatttcttgcatcaaattttacaaacccaattcaacgcgcatgcaagcccc
aaaagcgtcaacacccttttaggcattgcgaacgatattaaccagaatttagacgatagg
agtgaaatctatatcgctgaagccggggcaaggaataagggcgatattaaagaaatcacc
cgtctcattgaaccgcaccttgccgtgatcgcagaagtgggcgaacagcatttagaatat
tttaaaactttagaaaatatttgcgagactaaagcggaattattggattccaaacgctta
gaaaaagccttttgctactctgtggaaaaaatcaagccctatgcccctaaagatagccct
ttaacagatgtttctagcctggttagaaacgtccaatccactttaaaaggcacttctttt
gaaatgctgatagatagcgtttgggaaagctttgaaacgaaagttttaggggagtttagc
gcttataatatcgcttcagctattttagtcgctaagcatttaggcctagagacagaaagg
atcaaacggcttgtttttgagcttaagcctattaaccatcgtttgcaacttttggaagtg
aatcaaaaaatcatcatagacgatagctttaatgggaatttaaagggcatgttagagggc
attcgtttagcgagcttgcatcaagggcgtaaggtcattgtaacaccgggattagtggaa
agcaatacagaaagtaatgaggctttagcgcaaaaaatagatggggtttttgatgtcgct
atcatcacaggggagttgaattccaaaacgattgcttcccaattgaaaaccccccaaaaa
atcttactcaaggataaggcgcaattggaaaatatcttacaagccaccacgattcaaggc
gatttgattttattcgctaatgacgcccctaattacatttag
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