Hemicordylus capensis (graceful crag lizard): 128325858
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Entry
128325858 CDS
T08891
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
hcg
Hemicordylus capensis (graceful crag lizard)
Brite
KEGG Orthology (KO) [BR:
hcg00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hcg01001
]
128325858 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hcg04131
]
128325858 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hcg04147
]
128325858 (LRRK2)
Enzymes [BR:
hcg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
128325858 (LRRK2)
Protein kinases [BR:
hcg01001
]
Serine/threonine kinases: TKL group
LRRK family
128325858 (LRRK2)
Membrane trafficking [BR:
hcg04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
128325858 (LRRK2)
Exosome [BR:
hcg04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
128325858 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
COR
LRR_4
Ras
Ank_2
LRR_13
LRR_9
Arf
nSTAND3
LRR_NXF1-5
T2SSE
Arm
Gtr1_RagA
TrwB_AAD_bind
MMR_HSR1
Beta-prop_RSE1_2nd
AAA_16
PduV-EutP
AAA_22
ABC_tran
NACHT
Kdo
cobW
G-alpha
AAA_7
MobB
Septin
AAA_29
GTP_EFTU
FtsK_SpoIIIE
AAA_33
ResIII
UNC45-central
TniB
AAA_15
Motif
Other DBs
NCBI-GeneID:
128325858
NCBI-ProteinID:
XP_053107679
LinkDB
All DBs
Position
5:complement(153803051..153941156)
Genome browser
AA seq
2535 aa
AA seq
DB search
MASNRSKSSSWYEEEDEEKKEAALKKLIVRLKNVQEGKQIETLIQILEDLIAFASSQNGP
KLLNDKNTHVPLLLVLVSYMRVSSVQQVGWSLLCKLIEVCPDTLHNLASPQDIGKDWEVL
GVHQQILKMLKTHNANICLSTVGLRALNLLLSSDEITLLLLEEGTDVFLLVFDAMDTFSD
NEEIQKYGCKALHMLLEKVPEEQLIEFVEDKDHLIILNVFKKFPEKENVVLLALLSLHSL
AGPPSNVEVLMSGNVRSYNIVVEMMKTFPKSEPIQEVSCCLLHKLTLGNFFNILVLNNVH
EVIVKAVEKYPGNAKLQAAGLSCLALLTETIFLNRDLEEKEEDEEEGEKLCWLEACYKAL
KLHRKNIDVQEAACWALNNLLMYQHSLHEKIGDEEKKFPAHREVMLAMLMHSTSKEVFQA
AANALTTLSEQNESFRTVLLTKGIHINVLDIMKRHSNSPEVAESACKLLNHAFEGSFPPL
DIMTVAASRVVKVMMKHKLVPSVYLEALRVILHFVTPRAMTKQQNHTLEDAELTLMLKVI
QNQCVLEGTHILILDALNRFIGNPHIQKCGFQILSSVLKCSGALEMLSQQGMADTVLHTL
QMYPDDQEIQCLGLSLLGSLITRKSLCIATIHLLAAVLVSTLRRFKDVVEIQTHGFHTII
TILDLSPCFAKLLIQESFDTAIFYQMSMCFTEQRDQQFQSLCCKCFAKIAANEDLKNLML
EKACAEYNSIMVECLLLLRADVNKKTKTNSLIYQVCEKGSNPKLVELLLNSGAREQDVRS
ALMVSIKKGDSQIISLLLKKLSLDVANSSICLGGFCIGRIEPSWLSPLFPDKRTSFRKET
NAGSALARMVLRYQRKSSYEDQSRFGFNVTSSEDSVEKFDDWSVLPDPLIDNVFRLSDDL
DSEGSESSFLMKRKSSSVAAADLQKDTALQMGSPTAKRHSSFVGPGSHYETLGKPRRKAM
SSDELHGVSKFQSNIKRSDSFSSSVSDREYIKSLDLSSNELENIDGLSQSVSLTTHLEHL
EKLELQQNVLSHIPEQLCESLKCLKYLDLHSNHFTSFPVYLLKMPHIAHLDVSRNDIGPS
LVLAPKTDCTTLKLLNLSYNQLTHIPEFLSKVAEKLEHLILEGNKISGIFEPIHLKELKV
LNISKNALTSFVENVLKECLKLDILNAGMNSLDALPVLPFSITTLKLSQNNFSSVPEAVL
LLPHLRSVDLSNNEIISLPGPVHWKSSNLRELLFSHNKISVLDLNEKVFSWSRLEKLHLS
HNKLKEIPPQIGFLSNLTSLDVSYNPDLRSFPDEMGKLSKIWDLPLEGLHLNMDFKHVGW
KARDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKCKRQDLGIQKATVGIDV
NDWRVQIKGRVKKDLILNVWDFAGQEEFYSAHPHFMTRRALYLTVYDLSKGAAAVDAMKP
WLFNIKARASSSPVILVGTHLDISNEKERKACVSKITKELLNQRGFPAIQDYHFVNATEE
SDAMIKLRKTIIKESLNFKIREQPVVGQLIPDSYLELEKRILEERMHVPTGFPVIDQKRL
LELVEENKLQLDETELPHAVHFLNESGVLLHFQDPALQLRDLYFVDPKWLCKIMAQILTV
KVEGFPKYPKGIIKRSDAEQFLLKKNKFPKMYMSQYFKLLEKFQIALPLGEDQLLVPSSL
SDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEVSPYMLTGRERALRPNRMY
WRQGIYLNWSPEAYCLVESAIFENNPNSFLKITVPSCRKGCILLGQVVDHIDSLMEEWFP
GLLDVDVCGEGETLLKKWVLYSFEDGEEHQKILLDDLLKKAEEGDLLINPDRPKCTIPIA
QIAPDLILADLPRNIMLNNDGLEFDQRPEFLLGDGGFGSVYRASYDGEEVAVKIFNKHTS
LRLLRQELAVLCHLHHPSLVFLKAAAVRPRMLVMELAPKGSLDRLLQQDNANLTRTLQHR
IALHVADGLRYLHSSMIIYRDLKPHNVLLFTLYPNSAVIAKIADYGIAQYCCRMGIKTSE
GTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTAGGRILEGMKFPNEFDELAIHGKLP
DPVSEYSCAPWPEVEDLIKKCLKENPQERPTSDQVFEILNSAELVCLMRYISVSSASTAE
CMVATNSSCKKTGIWIGSGSTEAAQLSYIDLNTNEHTCQDIADTRILCLALVTLPAEKDN
WIVAGTQCGSLWAVHMQDEQHKHQLQRMSDSVTCLYCNSLAKQNKQKNFFLVGTADGQLA
VFEDRAIKCKGAAPLKILQVGNISTPLMCLSESNYSSEKNIIWGGCGTKIVSLSSDLAVQ
KLIETKASQLLCHKAYSDANIISIAVDKFIYLAKKNSYFVEIWDKKTEKLCELIDCVHFL
KEEVPNLNKETKQKLAYPGRVKSICLQKNTALWIGTGGGHILLLDLSTRHPLRIISDFCN
SVRFMMTAQLGSLKNVVLVLGHCHKDDSEDNKYAKGIQSCVSVWDINLPHEVQNLRKHIE
IRKELAEKMRSFSLD
NT seq
7608 nt
NT seq
+upstream
nt +downstream
nt
atggccagtaacaggagcaagagcagcagctggtatgaagaagaagacgaggaaaagaaa
gaagccgctctgaaaaaactgatcgtccggctgaagaacgtccaagaagggaagcagatt
gagaccttgatccaaatactggaagatctcattgcttttgcttcttcgcaaaacggtccc
aagttattaaatgacaaaaatacccatgtgcctttgctgctggttttggtttcttacatg
agagtgtcaagtgtgcaacaggtgggctggtcacttctttgcaaacttatcgaagtttgc
ccagacactcttcataatctagcatccccacaagatattggaaaggactgggaagtgctt
ggtgttcatcagcaaattcttaagatgcttaaaactcacaatgcaaacatatgcctttca
acagttggactcagagcattaaatctgcttctttcttcagatgaaataacacttcttctc
ttggaagaagggacagatgtgtttttattggtatttgatgcaatggacaccttttctgat
aatgaagaaatccagaaatatggatgtaaagctttgcacatgcttttagaaaaagttcca
gaggagcagctcattgagtttgttgaggacaaagatcatttgatcatactaaatgtattt
aaaaaattcccagagaaagaaaatgttgtacttcttgcacttttgtctctacattcactg
gctgggccacccagcaatgtggaagttcttatgtctggaaatgtgagatcttacaatatc
gtagttgagatgatgaaaacattccccaagagtgagccaattcaggaagtgagctgctgt
ttgttgcataaacttacactgggaaactttttcaatatcctggtattaaacaatgtgcat
gaagttattgtgaaggctgttgaaaagtaccctggaaatgcaaagctacaggctgcaggc
ctcagttgtttggctcttctcacggaaacaatatttttaaacagagacttggaagaaaaa
gaggaggatgaggaggaaggagaaaaattatgctggctggaagcttgttataaagcacta
aaattgcaccggaaaaatatagatgtgcaggaggctgcatgttgggctttgaacaatctg
cttatgtaccaacacagtcttcatgagaagattggagatgaagagaaaaagtttccagca
cacagagaagtgatgctggccatgctgatgcattctacttcaaaggaagtgtttcaagca
gctgcaaatgccttgacaactctgtcggagcaaaatgaaagttttaggacagtcctgttg
acaaaaggaatacacataaatgtgctggacataatgaagagacactccaactctcctgaa
gttgcagaaagtgcttgtaaactgctgaatcatgcttttgaaggaagttttccccctctg
gatataatgacagtagctgcatccagagttgtgaaggtgatgatgaagcataaattggtg
ccatctgtatatctggaggcacttcgagttattttacattttgtgaccccaagagcaatg
acaaaacagcaaaatcatactttggaagatgctgagttgactctaatgttaaaagtgatt
cagaaccaatgtgtcttggaagggacccatatactaatccttgatgcactcaacaggttt
attggaaatcctcatattcagaaatgtggatttcagatactttcctctgtattgaagtgt
tcaggtgctctagaaatgttgtcacagcaaggaatggcagatactgttctccatacacta
caaatgtatcctgatgatcaagaaatacagtgtcttggtttaagtcttctgggatctttg
attacaaggaagagcttgtgcattgcaactatacaccttctggcagcagttttggtttct
actttacgacgatttaaggatgttgttgaaatacaaactcatggattccacacaattata
acaatacttgatctatcaccttgttttgcaaagctgctaatacaggaatcatttgacaca
gctattttctatcagatgtccatgtgtttcactgaacaaagagaccagcagtttcagagt
ctttgttgtaagtgctttgctaaaatagctgccaatgaagatttaaaaaacctgatgttg
gagaaggcttgtgctgaatacaatagcattatggttgaatgtttgctgttgctgagagct
gatgtgaataagaagactaagacaaactccttaatttatcaggtgtgtgagaaaggaagc
aatccgaagttagtagaactgctactaaacagtggtgctcgagagcaggatgttcggtct
gctctaatggtcagcatcaagaaaggagatagccagatcattagcttgctcttaaaaaag
cttagcctggatgtggccaacagcagcatatgccttggaggcttctgcattggtagaatt
gaaccttcttggctgagccccctgtttccagataaacgaacatcattcaggaaagaaaca
aatgcaggttctgctttggcacgaatggttcttcgatatcaaaggaaaagcagttatgag
gaccagtcaagatttggttttaatgtaacttcctctgaagattcagtggagaagtttgat
gattggtcagtcctacctgaccctctaatcgacaacgttttccgcctgagtgatgatcta
gatagtgaagggagtgaaagctcatttcttatgaagagaaaatccagctctgtggcagct
gcggatctccagaaagacacagccttgcagatgggttctccgactgccaaaaggcactcc
agctttgtgggacctgggtcacattatgagaccttagggaagccaagaagaaaagccatg
tcttctgatgagctgcatggagtatctaaattccaatccaacataaagcggtcggacagt
ttctcttcatcagtctcagacagggaatatattaagtcactagacctttcatcaaatgag
ttggagaatatagatggcctcagtcaaagcgtttccttgactactcacttggaacatctt
gagaaattagagctgcaacaaaatgtactttcacacattccagaacaactgtgtgagagc
ttgaaatgtttgaagtatctggatctacatagtaaccattttacatctttccctgtatac
ctgttgaaaatgcctcatatagcacatcttgatgtctcacgtaatgacattgggccttca
ttagttttggctccaaagactgactgtacaacactaaaactactgaatttgtcatacaac
caattgacacacattcctgaatttctttctaaagttgctgaaaaattggaacatcttata
ctagaaggaaacaaaatttcaggtatatttgaacctatacacttgaaggaactgaaagtt
ttaaacattagcaagaacgctctgacttcctttgttgagaatgtgctgaaggagtgtttg
aaactggacatactcaatgctgggatgaattcacttgatgccttaccggtcttaccattc
agcataactacattaaaattatctcagaataatttttctagtgttcctgaagcagttctt
cttcttccacatttgcgctcagttgatttgagcaacaatgaaattataagccttccagga
ccagtgcactggaagtcctctaatttaagggagctgttgtttagccataataaaataagc
gtcctagacttgaatgaaaaagttttctcgtggtctcggcttgaaaagctacacctgtcc
cacaataagttaaaagagattcctcctcaaataggattccttagtaatttgacatctctt
gatgtaagctacaatccagacttaagatcctttccagatgaaatgggaaagctgtccaaa
atatgggaccttcctttggagggattacatcttaatatggacttcaaacatgtgggatgg
aaagccagagatattattagatttcttcaacagcgtttaaagaaagctgttccttataac
cggatgaagctcatgattgttggaaatactggcagtggtaaaactacactattgcagcaa
ctaatgaaatgcaaacgacaagatctggggattcagaaagctacagttggaattgatgtg
aatgattggagagttcaaataaaaggcagagttaagaaagatctgatattgaacgtctgg
gattttgcaggccaggaggaattctacagcgctcacccccactttatgactcggagagct
ctgtatcttactgtttatgaccttagcaaaggagcagctgcagtggatgctatgaagcca
tggctattcaatatcaaggcccgagcatcatcatcacctgtgattcttgttggtactcat
ttggacatctctaatgaaaaagagcggaaagcttgtgtcagtaaaattaccaaggagctg
ctgaatcagagaggtttcccagcaatccaggattaccattttgtgaatgctacagaagaa
tctgatgctatgataaaacttcgaaaaaccataataaaggagagtctgaatttcaaaatc
agggaacagccggttgttggacagctaatcccagacagctatttagaacttgagaagaga
attttagaggaacgtatgcatgttccaactggatttccagtgattgaccagaaacggtta
ttagaattggtggaagaaaacaagttgcagctggatgaaactgagctcccgcatgctgtt
cactttttgaatgaatcaggggtactgctgcattttcaagacccggcacttcagctacga
gacttatattttgttgacccaaaatggctgtgtaaaatcatggcacagatcttgacggtg
aaggttgaaggctttcctaagtacccaaaggggatcataaagcgttctgatgcagaacag
ttccttttaaagaagaacaaattcccaaagatgtatatgtctcaatatttcaagcttctg
gagaagttccagatagcactgccactaggagaagatcaactccttgttccaagcagcttg
tcagatcacaggcctgtgatagaattgccccactgtgaaaactcagaaattatcattagg
ctatatgagatgccatatttccccatgggtttttggtccaggctaatcaacagattgctt
gaagtgtctccttatatgttgaccggaagagaaagagctcttcgtcctaacaggatgtat
tggaggcaaggcatatacctgaattggtcacctgaagcatattgtttggtggaatcagca
atttttgaaaacaatccaaacagtttcctaaaaatcaccgtgccttcttgcagaaaaggt
tgtatcctcttgggtcaagttgtggatcatattgattctcttatggaagaatggtttcct
ggcttactagatgtggatgtatgtggggaaggggaaacactcctgaagaaatgggttctg
tatagttttgaggatggtgaagagcatcagaaaatattacttgatgacttacttaaaaaa
gcagaagaaggtgacctcttaataaatccagatcgaccaaaatgcaccattccaatagcc
cagattgcacctgacctgatactggctgatttacctagaaatataatgttgaacaatgat
ggactagaatttgaccaaagaccagaatttcttctaggcgatggtggatttggatctgtg
taccgggcttcttatgatggagaagaagtagctgtaaagatttttaataagcacacatct
cttagactcttaagacaagaacttgcagtgctgtgtcatcttcatcaccctagtttagta
ttcttgaaggctgcagcagtgcgtccccggatgcttgtcatggaattggctccaaagggg
tctcttgatcgattactgcagcaagacaatgcaaatttaacgagaaccctccagcacagg
atagctctgcatgtagctgatggcttaaggtatctacattcatcaatgattatctaccgt
gatttaaagcctcacaatgtgctgctttttacactgtatcccaattcagctgtcattgca
aagattgcagattatgggattgcacagtattgttgcagaatgggaataaagacttcagaa
ggcacaccaggatttagagcaccagaagttgcgagaggaaatgttatttacaaccagcaa
gctgatgtttattcatttggcttgctcctgtatgacattttaacagctggtgggagaata
ttagaaggcatgaaatttccaaatgaattcgatgaattagctatccatggaaaattgcca
gatcctgtctcagaatatagctgtgccccctggccagaagttgaagatttaattaagaag
tgtttgaaagaaaatcctcaggaaagacctacatctgaccaggtttttgagattttgaac
tcagcagaacttgtctgcttgatgagatatatttcggtatccagtgcttctacagcagag
tgcatggttgctactaattcaagttgtaagaagacaggaatctggataggtagtgggagc
acagaagcagcacagctctcctatattgacttaaatacaaatgaacatacttgtcaggac
attgcagacactagaatattgtgcttggccttggtgacccttcctgcagagaaggataac
tggattgtagcaggaacacaatgtggttctctgtgggccgttcacatgcaagatgagcag
cacaaacaccaacttcagaggatgtcagattctgtcacatgtctttactgcaactctctt
gcaaagcaaaacaagcagaagaatttctttttagtgggtacagctgatgggcagctagca
gtgtttgaagacagagcaataaagtgcaaaggggctgcacctttgaagatcttacaagtt
gggaacatcagcactccactcatgtgtttaagtgaatctaattattcatctgaaaaaaat
ataatctggggaggttgtggaacaaagattgtatccttgtccagtgacttggctgttcaa
aaactcattgagacaaaggcaagccaactattatgccataaggcttacagtgatgccaat
attatttcaatagcagtggacaaattcatctacttggcgaagaagaacagctattttgtg
gaaatttgggataaaaagacggagaaactttgtgaactaattgactgcgtgcattttcta
aaagaggaggtgccaaatctgaataaagaaacaaagcaaaaacttgcttatcctggaaga
gtgaagagcatctgccttcagaagaatacagctctctggataggcacaggaggaggacat
atcttattgcttgacctctccacgcgtcatcccttaaggataataagtgatttctgcaat
tcagttagattcatgatgacagcccagctaggcagcctcaagaacgttgttttggttttg
ggccattgccataaagatgatagtgaagacaacaaatatgccaaaggaatacagtcgtgt
gtatcagtttgggacattaatctgccacatgaagtacaaaacctgagaaaacatattgag
ataagaaaagaattagcagagaaaatgaggagtttttctttggattaa
DBGET
integrated database retrieval system
