KEGG   Hemicordylus capensis (graceful crag lizard): 128336398
Entry
128336398         CDS       T08891                                 
Symbol
TSC2
Name
(RefSeq) tuberin isoform X1
  KO
K07207  tuberous sclerosis 2
Organism
hcg  Hemicordylus capensis (graceful crag lizard)
Pathway
hcg04115  p53 signaling pathway
hcg04140  Autophagy - animal
hcg04150  mTOR signaling pathway
hcg04218  Cellular senescence
hcg04910  Insulin signaling pathway
hcg05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:hcg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    128336398 (TSC2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    128336398 (TSC2)
  09143 Cell growth and death
   04115 p53 signaling pathway
    128336398 (TSC2)
   04218 Cellular senescence
    128336398 (TSC2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    128336398 (TSC2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    128336398 (TSC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hcg01009]
    128336398 (TSC2)
Protein phosphatases and associated proteins [BR:hcg01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     128336398 (TSC2)
SSDB
Motif
Pfam: Tuberin DUF3384 Rap_GAP Cnd1 RHG29_45_N
Other DBs
NCBI-GeneID: 128336398
NCBI-ProteinID: XP_053131916
LinkDB
Position
13:complement(1476153..1517153)
AA seq 1803 aa
MAKPQSRDPGLKEKFKNLLGLGQPRPNSKSSEGKQTEYIITAEILKELSVECGLNNRIRA
IGQICEVAKTKKFEEHAVEALWKMVADMLNPDRPAEARHAVLHLLTAIIQGQGERLGILR
AHFFKVIKDYSSNEDLHERLEVFKALTDNGRDITYLEEELAEFVLQWMGIGLTSEFLLVL
VNLVKFNSCYLDDYIADMVHMICLLCIQTSSAVDIEVSLQVLDAVVCYNCLPSGTLPVFI
ITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRPYMADAALLRGAVFFVG
MALWGAHRLQSLKNSPTSVLPSFLKAMTCPNAVVSYEIVLSITRLIKKYGKDLQAVTWDI
LLEIIERLLQQLQTLESQELKSIVHDLLTTVEELCEQNEFHGSKEQYFELVERCADQRPE
SSVLNLITYKAQSIHPAKDGWIHKLQSLMERFFRNESRSAVRIKVLHVLSFVLSVNRQFY
EEELINLVVISQLAHIPEDKDHQVRKLATHLLVDLAEGCNTHHFNSLLDIIEKVASHSLL
PTAELEERDLLSYSASLEDVKTAVLGLLVILQTKLYSLPASHATRVYEMLVLHMQLHYKH
KYSLPIASSIRLQVFDFLLSLRADSLHRLGLASKDGLVRFSPYCLCDYAEPEKRSSEKKP
AGTLSPPSGSPSVPPQSSAIRTGHLPYSLLFGVLLQCLKQETDWKVLKLVLNKLPESLQY
QVLYLTSPCSVDQLSSALCSMLTDKKMTERLWGTPEGFSRNDLHLAVVPVLTALISYHNY
LDKSKQREMVYCLEHGLIYRCANQCVVALSVCSVEMPDIIIKALPVLIVKLTHISATANM
AIPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIK
CRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSRIQTSITSASLGS
ADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLV
GNKLVTITTSVGTGTRSLLGLDSGEQQNSMELSSDQVSQVRQTKEAPAKLESQAGPQVVR
GPRNRVRSMSGGHALRVGALDSSASHFPAGPAPQGPHSSPAPAARAEKAMPGAQTPLEKE
KANLSAFVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAE
RFKEHRETALYKSLSVPSSSLAPTGTAKPFLLQRSNTVPPLVFPFTVASFSSMYPSSSQE
RLHRSISWAESAVVLEEGSPPDTDLKESGFPPESQEIEDFEAMCQEQSLGEEKAGKDHGT
YSRSSSTSSQEERAPKPDALGPVGIPIERAGNLEESRAFEALSFQPSQPLSKSSSSPELQ
TLQEVLKDAGTEEPAGKLSSDLKSKSQSGHLEGEAARSWLGRGEEDRSPGAARLGGGGGG
GIPATSPRSPSGHRPRGYTISDSTPSRRGKRIERDPFKGRAAAPNAEKVPGINPSFVFLQ
LYHSPFFGDESNKPLLLPNETFERSVQLLDQIPPYDTHKIAVLYVGEGQSSNELAILSNE
HGSYRYTEFLTGLGKLIELKDCQPDKIYLGGLDVCGEDGQFTYCWHDDILQAIFHIATLM
PTKVLDKYRCDKKRHLGNDFVSIIYNDSGEDFKLGTIKGQFNFVHVVIKPLDYNCNLLTL
QCRKDMEGLVDTSIAKIVSDKNLPFVARQMALHANMASQVHHSRSNPTDTYPSKWIARLR
HIKRLRHRIREETQYQASGFPTMHHPSGPAKAAVPVPQDPAPTYETGQRKRLISSVDDFT
EFV
NT seq 5412 nt   +upstreamnt  +downstreamnt
atggcaaagccacaaagcagagatcctggcctgaaggagaagtttaagaacctcttaggc
ctcggccagccccggccgaactccaaatcgtcagaaggaaagcaaacggagtatatcatt
acagcggaaattctcaaggaactgagcgtagaatgtggcttgaacaaccggatccgggcc
attggtcagatctgtgaggtagcaaagacgaaaaagttcgaagagcatgcggtggaagct
ctctggaagatggtggccgacatgctgaatccagatcggcccgcggaggccaggcacgcc
gtgctgcacctgctgacggccattatccaagggcagggcgaaaggctggggatcctccga
gctcacttcttcaaggtgatcaaggattattcttcgaacgaagacctgcacgaacggctc
gaagtcttcaaggccctcaccgataacgggagggacatcacgtacttggaagaggagttg
gctgaatttgtccttcagtggatgggcatcggtttgacttccgagttcctcctggtgctg
gtcaacttagtcaagttcaacagctgctacttggacgattacatcgccgacatggtccac
atgatttgcctcttgtgcatccagacgtcttctgcagttgacattgaggtttccctgcaa
gtcttggatgctgtggtctgctataactgcctgccttctggaaccctccccgtctttatc
atcactctgtgccggaccatcaacgtcaaggaactctgcgagccgtgctggaagctcatg
cgtaacctgctggggactcatttggggcacagcgccatttacaacatgtgccggatcatg
gaggacagaccctacatggcagatgcagcattgctgaggggagccgtgttcttcgtgggg
atggccctatggggagcacacaggctgcagtcgctcaagaattcgccaacctcagtgctc
ccctccttcctgaaggctatgacgtgtccaaatgctgtggtgtcttacgaaatagtcctc
tccataacgaggctgatcaaaaagtacggaaaggatctccaggccgtcacttgggacatc
ctcctggagatcatcgagcggttgctgcagcagctgcagaccttggagagccaggagctg
aaatccatcgtccacgacctgctgaccacggtggaagagctgtgcgagcagaatgaattc
catggctccaaggagcaatattttgagctcgtggaaagatgtgctgatcagaggcctgaa
tcttcggttctgaacctgataacatacaaagctcagtccattcaccctgcaaaggacggc
tggatccacaagctgcaaagcctgatggagaggttcttcaggaatgagagtcggagtgct
gtccgtatcaaagtgctacacgtcctgtcttttgtcttgagcgtcaaccggcaattttac
gaggaggagctgattaacctggtggtcatctcccagctggcacacatcccagaagataag
gaccaccaagtccgcaagctggccacccacttgctggtggacctggccgagggctgcaac
acccatcacttcaacagcttgctggacatcatagagaaggtggcttctcattccttgctg
ccgacggctgaactggaggaaagagacctgctctcctactctgcctctttagaagacgtg
aagacggctgtgttgggccttctagtcattctccagacaaagctgtacagcttgccggcc
agccacgccacccgggtctacgagatgctggttctgcacatgcagctccattacaagcac
aagtacagcctccccattgccagcagcatccgactgcaggtgtttgacttcttgctctcg
ctgcgggccgactccctccaccggctgggcctggccagcaaagacggcctggtgcgcttc
agcccctactgcctctgcgactacgcggagcccgagaagaggagttctgagaagaaaccg
gctggcaccctctccccgccctccggaagccccagcgtgcccccccagagctctgccatc
cgaaccggccatctcccgtactccctgctctttggggttctcctgcagtgcttgaagcaa
gagacagactggaaggtgctgaagctggtgctgaacaagctgccggagtccctgcagtac
caagtgctctacttgacttcgccgtgcagtgtggatcagctgtcctctgccctctgctcc
atgctcacagacaaaaagatgacagagcgtctgtggggcacccccgaaggcttctcccgc
aacgacttgcacttggccgtggtcccggtcttgaccgctttgatctcgtaccacaactac
ctggacaaaagcaagcagcgggagatggtttactgcctggagcacgggctgatctaccgc
tgcgctaaccagtgtgtggtggctctgtcagtctgcagcgtggagatgccggatattatc
atcaaggccttgccggtcctgatagtcaagctgactcacatttcggccacggccaacatg
gccattcctctcctggaattcctttcaaccctggcccgcctgcctcatctctacaggaac
tttgcggcggagcagtatgcaagcgtctttgcaatctccctgccctacaccaacccctcc
aagtttaaccagtacatcgtgtgcctggcgcaccacgtgatagccatgtggttcatcaag
tgccgtctgcccttccggaaagactttgtcccgtatatcaccaagggcttgcgttcgaac
gtgctcctctccttcgacgacaccccagagaaagacagcttccgggctcgcagtacaagc
ctgaacgaaaggcccaagagccgcatccagacctccatcaccagcgccagcctggggtct
gctgatgagaactccatggcccaagcagacgacaacctgaaaaacctccacttggagctc
acggagacctgcctggatatgatggcccgatatgtcttctccaacttcacagctgtgccc
aaaaggtctcccgtgggggagttcctcctggccggagggcgaaccaagacgtggctggtg
ggcaacaagctggtgacgatcacgacgagtgttgggacggggaccaggtcgctcctgggc
cttgactctggggagcagcagaacagcatggagctgagctcagaccaggtctcgcaagtg
cggcagaccaaagaagcccccgcaaagctggagtcgcaggctggcccccaggtggtccga
gggccccgcaacagagtcaggtccatgtctgggggccacgctttacgggtcggggcgctg
gacagctcggcttcccatttcccagccggcccggcaccccaaggaccacacagttctcct
gcacctgctgctcgggcagagaaggccatgcctggggctcagacgcctctggagaaggag
aaagccaacttgtccgccttcgtcccactgctcacccaaggctgggcagaaatactggtc
cggaggccaacagggaacaccagctggctgatgagcctggagaacccgctcagccccttt
tcttcggacatcaacaacatgccgctgcaggagctctccaacgccctcatggccgccgag
cgcttcaaagagcaccgcgagacggccctctacaagtccctctcggtgccctcctccagc
ctggcccccaccggcacagccaagccctttctcctgcagcgctccaacacagttcctccc
ttggtttttcccttcacagtggcctctttctcttccatgtacccgagcagttctcaagag
aggttgcacaggagcatttcctgggcagaatctgcggtcgttctggaagaaggaagccca
ccagacacggacttgaaagaaagcgggttccccccggagtcccaagagatcgaagacttt
gaagccatgtgccaggagcaaagcctaggcgaggagaaagctggcaaggaccatgggacg
tacagcaggtcctcttccacctccagccaagaggagagagccccgaagccagacgccctg
gggcccgttggcatccccatcgaaagggccggcaacctggaggagagccgggcgtttgag
gccctctccttccagccttcccagcccctcagcaagtccagctcctctcccgagctccag
accctccaggaagtcctcaaggatgccggcaccgaggagccggctggcaagttgagcagc
gacctgaagtccaagtctcagtctggccacctggaaggcgaggcggccaggagctggctg
gggagaggggaagaggaccggagccccggggcagccaggctgggcggcggcggcggcggc
ggcatccctgccacttcgccccgctccccgagtggccaccggccccgaggctacaccatt
tctgactcgacgccctcgcggagaggcaagaggatcgagagagaccccttcaagggcaga
gcggcggctcccaacgcggagaaggtgccagggatcaacccaagctttgtgttcctgcag
ctgtaccactctcctttctttggtgacgaatccaacaagccccttttattgcccaacgaa
acctttgagagatctgtgcagctcctggaccagatccctccctacgacacccacaagatc
gccgtcctgtacgttggagagggacagagcagcaacgagctggccatcctctccaacgag
cacggctcctaccgctacacggagttcctgacgggcctgggcaagctcatcgagctgaaa
gactgccagccggacaagatctacctgggcggcctggatgtgtgtggggaggacgggcag
ttcacctactgctggcacgacgacatcctgcaagccattttccacattgccacgttgatg
cccaccaaagtcttggacaaatatcgctgcgacaagaaacggcacctggggaacgacttt
gtctccatcatttacaacgactctggggaggacttcaagctggggaccatcaagggtcag
ttcaacttcgtgcatgtcgtgatcaagcccctggattacaactgcaacctgcttaccctc
cagtgccggaaagacatggaaggtcttgtcgacaccagcattgcgaagatcgtctctgat
aaaaacctgccctttgtcgcccgtcagatggcgctgcacgccaacatggcttctcaggtc
catcacagccgctccaaccccacagacacctacccatcgaaatggatcgctcggctgcgg
cacatcaagagactccgacacaggatccgagaggaaacccagtaccaagcgtccggcttc
cccaccatgcaccacccttcaggccctgccaaagccgcggtccccgtgccccaggaccca
gcccccacctacgagacggggcagaggaagcggctcatctcctcggtggatgacttcaca
gagtttgtttag

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