Hemicordylus capensis (graceful crag lizard): 128340763
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Entry
128340763 CDS
T08891
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
hcg
Hemicordylus capensis (graceful crag lizard)
Pathway
hcg00270
Cysteine and methionine metabolism
hcg00480
Glutathione metabolism
hcg01100
Metabolic pathways
hcg01240
Biosynthesis of cofactors
hcg04216
Ferroptosis
Module
hcg_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
hcg00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
128340763 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
128340763 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
128340763 (GCLC)
Enzymes [BR:
hcg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
128340763 (GCLC)
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
128340763
NCBI-ProteinID:
XP_053142351
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Position
1:complement(295024208..295058362)
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AA seq
637 aa
AA seq
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MGLLSQGSPLTWEETQRHAEHVRKHGILQFLHIYRAVGERHKDVLKWGDEVEYMLVAFDH
ENKRAQLSLTGEEVLHTLQEKGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRLEAASVLKQNEALCTVTSFPRLGCPGFTMPEYDPTPVETGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTRSPFIETFPNDDGEAGRAAQPDHVYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAAAPFYRGYVTDIDCRWGV
ISASVDDRTREERGLEPLKNNRYRINKSRYDSIDSYLSECGEKYNDIDLTVDKEIYNRLI
NEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMAVAQKRDAV
RQGMFYFRKDICKGGNAVVDGCGTAQNGTETDAEEYTLMSIDTIINGKEGVFPGLIPVLN
SYLENMEVDVDTRCSILNYLKLIKKRASGELMTAARWMREFIANHPEYKQDSVITEEMNY
SLIWECNQIAQEQVECPELLGVGFNKVKYSGTKTGTF
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctcctgtcgcagggctccccgctgacttgggaggagacgcagcggcacgcagag
cacgtgcgtaaacacggcattctccagttcctgcacatctaccgagccgtcggagaaagg
cacaaggacgtgctgaagtggggggacgaggtggaatacatgttggtagcatttgaccat
gaaaataagagagcgcagttgtctttaactggagaagaagttcttcatacattgcaagaa
aagggtgaaaagataaaccctaaccatccaactctctggaggcctgaatatggaagctat
atgattgaagggactcctgggcagccctatggaggaacaatgtctgaattcaacactgtg
caagataacatgaggaaacgacgtctggaagctgcttctgtgctgaaacaaaatgaagct
ctttgcactgtcacatcatttccaagattagggtgtccaggatttacgatgccagaatat
gacccaacacctgttgagacaggagcatccaagtctctcttctttccagatgaagctatc
aataaacatccaagatttagtactttaacaagaaacattcgacacagaagaggagaaaaa
gtagtgataaacgtaccaatatttaaggataagaatacacggtcaccatttatagaaaca
ttccctaatgatgatggtgaagcaggaagagcagcccagcctgaccatgtatatatggat
gccatggggtttggaatgggcaactgctgccttcaggtaacattccaggcttgcagcatt
tctgaagcaagatatctttatgatcagcttgctacaatctgccccattgtgatggcatta
agtgctgcagctccattctacagaggctatgtgacagatattgattgtcgttggggagta
atatctgcatcagtagacgacaggacaagggaggaaagggggttagagccactgaagaac
aaccgctacagaatcaataaatccagatatgattccatagacagctacctatctgaatgt
ggtgaaaaatacaatgacattgatttgacagtagataaagaaatctacaatcgcctaata
aatgaaggcattgaccatcttctggcacaacacattgctcacttatttattcgagatcca
ttgactttgtttgaagagaaaatacatctggatgatgcaaatgaatcggaccattttgag
aatatacagtcaacaaactggcagacgatgagatttaaaccgcctcctccaaattcagat
attggctggagagttgagttcagacctatggaggtccaactaacagattttgaaaattct
gcgtatgttgtgtttgtagtgctgctgacccgtgtcattctctcatacaaactggatttt
ctcattcctttgtcaaaggtggatgagaacatggcagtagctcagaaacgggatgctgtc
cggcagggcatgttttatttcagaaaagacatttgtaaaggtgggaatgctgtagtggat
ggatgtggcacagctcaaaatggtacagaaacggatgcagaagagtataccttaatgagc
atagatacaataatcaatggaaaggagggagtatttcctggcttaattccagttttaaac
tcttaccttgaaaacatggaagtggatgtggatacaagatgcagcattctaaactacctg
aagctaataaagaagagagcgtcaggagaattaatgacagctgctcgatggatgcgagaa
ttcattgcaaaccatccagagtacaaacaggacagtgtgatcactgaagaaatgaattac
agcctgatttgggaatgcaatcagattgcgcaagagcaagttgagtgccctgagttgctt
ggagtaggctttaacaaagtaaaatacagtggaacaaaaactggcactttttga
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