Hemicordylus capensis (graceful crag lizard): 128342549
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Entry
128342549 CDS
T08891
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
hcg
Hemicordylus capensis (graceful crag lizard)
Pathway
hcg04217
Necroptosis
hcg04620
Toll-like receptor signaling pathway
hcg04621
NOD-like receptor signaling pathway
hcg05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
hcg00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
128342549 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
128342549 (TYK2)
04621 NOD-like receptor signaling pathway
128342549 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
128342549 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hcg01001
]
128342549 (TYK2)
Enzymes [BR:
hcg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
128342549 (TYK2)
Protein kinases [BR:
hcg01001
]
Non-receptor tyrosine kinases
JAK family [OT]
128342549 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
Kinase-like
Kdo
FERM_C_FAK1
SH2
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
128342549
NCBI-ProteinID:
XP_053145927
LinkDB
All DBs
Position
2:180583262..180657913
Genome browser
AA seq
1219 aa
AA seq
DB search
MAPGKGEAEQGASWRRWRRQTACRARDLGTGKMPLCHCAVKHSESDMEGCRFSPAGQLRV
YLHWKGDQEEEPYQTYTQGTLCAEEICIDIAQKIGITPVCYSLFALYDPQAKLWFPPNHV
FEISSSIKLTLHFRMRFYFRNWHGMNDKEPAFCRSIPRLSDSEDKSHRGDHGSALLDKSS
FEYLFEQGKHDFINDIASLKDLRTEQELHQFKNESLGMAVLHLCHIALKRRISLEEVAER
TSFKECIPRSFCRQIQQNNYLTKFRMRNVFKKFLQRFQQHTVSTGKLIEQDIMYKYLSTL
ENLAPRFGTERFQVLSLETISEGEKVPLYINGGHTHLENSHASPLSDRPATHEVLITGTE
GIQWWPISTEKLESRPHKGYLGRKARTKDPKLKWPYQPVERHEPKWVHFCDFQEITHVVV
KDCQVSIHRQDNKCLDLTLPSSEAALSLVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIQ
NGIHGPMQEEFILAKLKREEQEEGLYVLRWSVLDFNSLILSVLRRGQSFRIQDTTSYRQL
RIQKKGNSFALEGWDQEFSSVQELMNALKRCNLRSGNEIFSLKRCCLPKPGEVSDLLIAR
KVKDSTRQILNLSQLSFHQIRKNEITQRAHLGQGTCTNIYDGVLHVSGGTTGDDETEYFS
TEQNNNSREIHVVLKMLDPSHRDIALAFFETASLMSQVSHIHLAFVHGVCVRGSENIMVE
EFVEHGPLDVFLRKHKGQIIVGWKFTVAAQLASALSYLETKNLVHGNVCAKNILLARKGL
EDGSLPFIKLSDPGVNFTVLSREERVDRIPWIAPECVKDVSNLSTAADKWSFGTTLLEIC
FDADVPLKERTPSEKERFYEKKHRLPEPAFKELATLISQCLNYAPGERPSFRTILRDLTQ
LQPHNLLDITTVNPECPISDPTVFQKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA
VKSLKSGCSQQLLTSWKKEIEILKTLYHENIVKYKGCCSEQGEKIVQLIMEYVPLGSLRD
YLPKHNVCLAHILLFAQQICEGMAYLHSLRYIHRDLAARNVLLENENVVKIGDFGLAKAI
PEGHEYYRVCEDGDSPVFWYAVECLKECKFYYTSDVWSFGVTLYELLTRCDSSQSPPTKF
IEMIGATQGQMTVLRLIELLDRGKRLPIPKDCPYEIYRLMKNCWESEASFRPAFTNLVPI
LRAFHEKYRAQAPSVFSVC
NT seq
3660 nt
NT seq
+upstream
nt +downstream
nt
atggcgccggggaagggggaagcagagcagggggcgagctggcggcggtggcggcggcaa
acagcctgtcgggctagggacttggggactggcaaaatgccgctgtgccattgtgcagtg
aagcacagtgagtcggacatggaggggtgccgtttttcacctgctggacagctgagggtg
taccttcactggaagggtgaccaggaggaggaaccttaccagacttacacacaggggact
ctctgtgctgaagagatctgcattgatattgcgcagaagattggtatcacaccagtctgc
tacagcttgtttgcactttatgatccacaggccaaactatggtttccccccaaccatgtg
tttgaaattagcagcagcatcaagttgaccctgcattttcgcatgaggttttatttccga
aactggcatgggatgaatgacaaggagccagctttctgtcgcagcattcctcgtttaagt
gactcggaggacaagtcacacaggggtgatcatggcagtgcccttctggataaatcatca
tttgaatatctctttgagcaagggaaacatgacttcattaatgatattgcctctctaaaa
gacctacgcaccgagcaagagcttcaccagtttaaaaatgagagcctggggatggctgtc
ctccatctctgtcacattgctctcaaaagacgcatatctcttgaagaagtggcagagaga
accagcttcaaagagtgcatcccacgctccttctgccggcagattcagcagaacaattac
ctaaccaagttccgcatgaggaatgtcttcaagaagttcttgcagcgcttccagcagcac
acagtgagcactggcaagctaatagagcaagacatcatgtacaaatacttatcaactttg
gagaatttggctccacgatttgggactgagcggttccaggtcctctcgctggaaaccatt
tcagagggtgagaaggtgcccctttatatcaacggagggcatactcatttggagaattcc
catgcttctcctcttagcgacaggcctgccacacacgaggtcctgatcacaggcacagaa
ggcattcagtggtggcccatctcaactgagaaattggaaagccgtccccataagggttat
ttgggaaggaaggccagaactaaagaccccaagctcaaatggccctaccaaccagtggag
cgacatgaaccaaaatgggtccacttctgtgacttccaggaaattacacatgttgttgtc
aaggattgccaagtcagcatccatcggcaagacaataagtgcttggacctgactttgcca
tcctctgaggctgctctctccttggtttcactggtggatggttacttcagattgacagct
gactccagccactatctgtgccatgaagtagccccaccgcggctggttatgagcattcag
aatggtatccatggacccatgcaggaggagttcatattggctaagctgaagcgggaggag
caagaggaagggttgtacgttctccgctggagtgttcttgacttcaatagtttgatcttg
tcagtactaaggagaggccagagcttccggatccaggacaccacaagctacagacaactt
cggatccagaagaagggaaattcctttgcactggaaggctgggatcaggagttctctagt
gtccaggaactgatgaatgctctcaaacgttgcaatctgagatctggcaatgagatcttt
agtttgaagaggtgttgtctcccaaagccaggagaagtctcagacttgctaatcgcacga
aaagtaaaggacagcaccaggcagattctgaacttgagtcaattgagcttccaccagatt
cgaaagaatgagatcacccagcgtgctcacttgggacaagggacatgcaccaacatttac
gatggtgtgctacatgtgagtggtgggaccactggtgatgatgagacagagtacttctcc
acagagcagaacaacaacagccgtgaaatacacgtcgtgctcaagatgctggatcctagc
cacagggacattgctttggcattctttgaaacggccagcctaatgagccaggtctcccac
atccacttggcctttgtgcatggagtttgtgttcggggctcagagaatataatggttgaa
gagtttgttgaacatggtcccctggatgtcttcttgcggaaacacaaagggcaaataata
gtgggctggaaattcactgttgctgcacagttagctagtgctttgagctacttggaaacc
aaaaacctagtgcatggcaatgtatgtgccaagaacatcctgctggccaggaaaggctta
gaagatggttcattgcccttcattaagctcagtgaccctggagtcaacttcactgtgctg
tcccgagaagaacgagttgaccggatcccatggattgctccagagtgtgtcaaagatgta
agcaacctcagcacggcagctgacaaatggagctttggtaccacgctgctggagatatgc
tttgatgcagatgtgccactgaaagaacgcactccttctgagaaagagcgtttctatgag
aagaaacaccgccttccagagccagctttcaaagagctagctaccctgatcagccagtgc
ctgaactatgctcctggggaacggccttctttccgaaccatcttgcgagaccttacccaa
ttgcagccacacaatctccttgacatcactactgtgaaccctgaatgtcctatatcagac
cccactgtttttcagaagcgctacctgaagaagatcagagaccttggagagggtcacttt
ggcaaagtgagtttgtactgctatgatcccaccaatgatggtactggcgaaatggtagca
gtgaaatcattgaaatctggctgcagtcagcagcttctgaccagctggaagaaggaaatt
gagatcctgaagacactctaccatgagaacattgtcaaatacaagggctgctgcagtgag
caaggtgaaaagattgtgcagcttattatggagtacgtgcctttggggagcctgagggat
tatctacccaagcacaatgtctgcttggcccacatcctcctctttgcccagcaaatttgt
gagggaatggcctatctccactccctgcgctacatccatagggatctggcagccaggaat
gtgctcctggagaatgagaatgtggtgaagattggagactttggtcttgccaaagccatc
cctgaaggacatgaatactaccgtgtctgtgaagatggagatagtcctgtcttctggtat
gctgttgagtgcctgaaggagtgcaaattctactacacctccgatgtctggtcctttgga
gttactttatatgaactcttaactcgctgtgattctagtcagagccctccaacgaaattc
attgagatgattggagcaactcagggtcaaatgacagtgctgaggcttatagagctgctg
gatagagggaagaggctgcccatcccaaaggactgtccttacgagatttaccgcctgatg
aaaaactgttgggaatcagaagcttccttccgcccagccttcacgaaccttgtgcccatt
ctcagagccttccatgaaaagtacagggcccaggctccctcagttttcagcgtatgttga
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