Hemicordylus capensis (graceful crag lizard): 128343215
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Entry
128343215 CDS
T08891
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
hcg
Hemicordylus capensis (graceful crag lizard)
Pathway
hcg00310
Lysine degradation
hcg01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
hcg00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
128343215 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hcg03036
]
128343215 (DOT1L)
Enzymes [BR:
hcg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
128343215 (DOT1L)
Chromosome and associated proteins [BR:
hcg03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
128343215 (DOT1L)
HMT complexes
Dot1-containing complex
128343215 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
128343215
NCBI-ProteinID:
XP_053147849
LinkDB
All DBs
Position
2:complement(211251895..211340938)
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AA seq
1750 aa
AA seq
DB search
MGERLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDKEFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGQIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRETKSNTTTPTKVP
ENKDYGAEEDRSLRANTIKKPSPSKARKKKLSKKGRKMVGRKRGRPKKMNVGSSERKTKK
NQTALELLHAQTVSQACSSSPQDAYRSPRSPYYQLPPKVQRHSSNQLLVTPTPPALQKLL
DSFKIQYMQFMAYMKTPQYKANLQQLLEQEKEKNTQLLGKAQQLFSHCQAQKEEIKRLLQ
QKLDELGVKALTYNDLIQAQKEISAHNQQLKEQTKQLEKDNGELRNQSLQLLKARCEELK
LDWSTLSLENLLKEKQALKNQISEKQKHCLELQISIVELEKSQRQQELLQLKSYMPPDES
LPRHKSHPPREPEPGHGMFHLELECSKFPVPHLNGMSPELSMNGHATSYEIHQALGRPSS
KQSTPQYAASHLDQEIVPCTPSHACRQKPDKASSLSLPDYTRFSPAKIALRRHLNQDHAG
SGKAAANENHPRAEHIKENGLLFPSPTIANGIKMSPQEARPSSPAALPIASEKALRERTS
VNNGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRVEKVRSTPSPVHQNRDSFSTLE
KPFGASSHNGSVSNPAGNKPLTLATSGFPCLPGSTLVNGTLSSSPAQLNHSFDHTALEDV
SSSGSLFNSAGSRSSTPQHPSLLMMPSWNSGQNSPAHQHSASPQLNGAPPGLGGVLQYVE
GTRGDPQPNPAFSDPESETKGRIIFTISPTTGTIKHSPSSKHGPLTASIRMECGPAYGQD
GKKRGRRKRSSTGTPGVNSGVSPKRKSLPTVAGLFTQSSGSPLNISSMVSNINQPLEITA
ISSPENSLKNSPVPYQDNDQPPVLKKEKPLGQSNGIHYSPLTSDEEQGSEDDRNSTRIER
KIATISLESKSPQKPVENSISLTGRKPASENVNSSKWKSTFSPISDINLTKPVDSPLQAP
PPLSQNSLFAFRPPAEDGAAGEAKAGSQGRKHTAGDAKAGPEGLGLCANSVNGFAYNGGL
SVDLGLHSFIDGASLPHKAADAAAAAPALGSSSSLGFLVQRNKEAGLSDSNPFLSKRQLD
SLGAAKGEDLNWPGPKSREAGELGVRLGGSSEKASVLHNGKIGKGRERDVEFKNGHNLFI
AAAAAAVPSGGLLNGKAAAAANPAASSAQTHHSFLNSLAAGSQFSLGPMVTTASVLQTLF
NSMPATGLVPVSSAATRLSNAHAMGSFSPGVTGGTVGGIFNHVVPSASSSSSSFTPSPSI
SSSSFSSSSSSSSLPFGASLGHGAGSSCAVLSLTPPQVAAGSPSLHVPPHPPPPSDAQHL
SRATAPPSLRSPPPPNVSLPPPPPLLASHSEPVLLQSMSSLPAAEAFLPPSSSSSSSTTA
NSALSLKLASLQHKTACPSFTVHHPPLPRLALAQAAPGIPQSTAAGPPAMWVTLGMQSPY
ASHLSGVKPR
NT seq
5253 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaggctggaactccggctgaagtcgcccgttggagccgagccggccgtctac
ccctggcccctgcccgtctacgacaagcaccacgatgctgctcatgaaatcattgagaca
attcggtgggtctgcgaagaaattccagacctcaagcttgctatggaaaactacgtttta
attgactacgatactaaaagctttgaaagcatgcaacggctttgtgacaaatacaaccgt
gccatcgatagcattcaccaattgtggaaaggaaccactcagcccatgaagctcaatacc
cgcccctccaatgggctcctccgccatatcctccagcaagtctataaccactcggtgacc
gacccagagaaactcaacaactatgagcccttttccccagaggtgtacggagagacgtcc
tttgacttggtggcccagatgatagatgagatcaagatgacggaagacgacctgtttgtc
gacttgggtagtggtgtgggccaagtcgttctacaagtagctgcggccaccaattgcaaa
catcactatggtgtggagaaagctgatattccggccaaatacgctgagacgatggacaaa
gaattccgaaagtggatgaaatggtatgggaaaaaacacgcagaatacacactggaaaga
ggggactttctctcagaagagtggcgagagagaattgcaaacacaagtgttatctttgtg
aataactttgcctttggtcctgaggtggatcaccagttgaaggagcgatttgcaaacatg
aaggaaggtggccaaattgtctcttcgaaaccttttgcaccgctaaactttagaataaac
agtcgaaacttgagtgacattggcactatcatgagggttgtcgaattgtccccactgaaa
gggtctgtctcgtggaccgggaaaccagtttcttactacctgcatactattgatcgaacc
atacttgaaaattacttctctagtctcaaaaacccaaaactcagggaggaacaagaggca
gctagacgccgacagcagagagagaccaagagcaacacaacgaccccgacgaaggtcccc
gaaaacaaggactatggtgctgaagaagatagaagccttcgggccaacaccatcaaaaag
ccatctccgtccaaagcacggaagaagaagctcagcaaaaagggaaggaagatggtgggc
cgaaagcgtgggcgccccaagaagatgaacgtcgggagctcggagcgcaagaccaagaag
aaccagacggcgctggagctcctccacgctcagaccgtgtcccaggcatgctcatcctct
cctcaggatgcatacaggtcacctcgtagtccatattaccaactacctcctaaagtgcaa
cggcattcttcaaatcagctgttggtgactcccacccctcctgcactacagaagctgcta
gactcttttaaaatccagtacatgcagttcatggcgtacatgaagactcctcagtacaag
gcaaaccttcagcagctgctggaacaggaaaaggaaaagaatactcagttactggggaaa
gcgcagcagctattttctcactgtcaggctcagaaagaagagatcaagcggctgcttcag
cagaagctggacgagctgggcgtgaaggcgctgacgtacaacgacctcatccaagcgcag
aaagagatctcggctcacaaccagcagctgaaggagcagaccaagcagctggagaaggat
aacggtgaactcaggaaccagagcctgcaactgctgaaggccagatgtgaagaactgaag
ctggactggtccacactgtcactggagaatctgctgaaagaaaagcaggcactgaagaac
cagatttccgagaaacagaagcactgcttggaactgcagatcagcatcgtggagctcgag
aagagccaacggcagcaggagcttctgcagttgaagtcgtacatgccacctgacgaatcg
ctgccccgccacaaaagccacccgccccgcgagcccgagcccggccacggcatgttccac
ctggagctggagtgttccaagttccccgtgccccacctgaacggcatgagccccgagctc
tccatgaacggccacgccacctcctacgagatccaccaggccctcggcaggccctcctcc
aagcagagcaccccgcagtatgccgcctcgcacctggaccaagagatcgtcccttgcact
cccagccatgcctgccggcagaagccagacaaggcctccagtttgtccttgccggattac
acccggttttccccggctaagatcgccctccggaggcatctgaaccaagaccacgcaggc
agcgggaaagcagcagcgaacgagaaccatccaagagctgagcacataaaagagaacggc
cttctgtttccgagcccgacgatagcgaacggcataaaaatgagccctcaggaagcccgg
ccctcctctccagcagccttgcccatcgccagcgagaaggctttgagagagaggacgtcc
gtgaataacggggagaccatcaccagcctccccatcagtattcccctcagcacggtgcag
cccaataaactccctgttagtatccccctggccagcgtagttctacctagccgtgttgag
aaggtgaggagcacacccagccctgtccaccagaaccgcgactccttttcgacacttgaa
aaaccatttggtgctagttctcataacggcagcgtcagcaaccctgctggcaacaagcca
ctgactttggctacctcaggttttccttgcctgcctggctccacactggtcaacgggacc
ctttcgagcagccccgcccagctgaaccacagcttcgaccacacggctctggaagacgtg
tccagttcaggaagcttgttcaattcggcgggctctcggagctccacacctcagcacccc
tccttgctcatgatgccctcctggaattccgggcagaactcccccgcgcaccagcactcg
gctagcccccagctgaacggggctcccccgggcctgggcggggtcctgcagtacgtggaa
ggcacccgaggcgacccgcagcccaacccggccttctcggaccccgaaagcgagaccaag
gggaggatcatcttcaccatctcgcccaccacggggaccatcaagcattctccctctagc
aagcacggccctctcaccgcaagcatccggatggagtgtggcccggcctacgggcaggac
gggaagaagcgtggccggaggaagcgctcctccacagggacgcccggcgtgaactctggg
gtgtcgcccaagcgcaagtctctgccaacggtggcgggtctcttcacccagtcgtcgggg
tctccccttaatatcagctcaatggtcagtaacattaaccagcctttagaaataacagcc
atttcttcccctgaaaactcgctgaagaactctcctgttccataccaggataacgaccag
ccacccgtgcttaaaaaggagaagccccttgggcagagcaatggcatccattactcaccg
ctgacctcggacgaggagcagggctcagaagacgaccggaacagtaccagaatcgagagg
aaaatcgcaacaatatcgctggaaagcaaatcgccgcaaaagccggtggagaacagcatc
agcttaaccgggcggaagccagccagcgagaacgtcaacagcagcaagtggaagtccacc
ttctctcccatttccgacatcaacctgaccaaaccggtggacagccctttgcaagccccg
ccgcccctgagccagaactccctctttgccttcaggccgcccgccgaggacggcgccgct
ggggaggccaaggccgggtcccaggggaggaagcacacggctggggacgccaaggccggg
ccagaggggctggggctgtgtgctaactccgtgaacggctttgcgtacaacggggggctg
tcggtggacctcggtttacatagctttattgacggtgcttcgctcccccacaaagccgcc
gacgctgccgccgcggcgccggcactggggagctcctcctcgctgggcttcctggtgcag
cggaacaaagaagccggcctctctgactcgaatccgttcctgagcaaaaggcagctggac
agcctgggggccgccaaaggggaggacctcaactggccgggccccaaaagcagagaggcc
ggggagctgggcgtccgcttggggggctcttcggagaaggcctcggtgctacacaatggc
aaaatcggcaagggccgggagcgggacgtagagttcaagaacggccacaacctcttcatt
gccgccgcggccgccgctgtaccgtcgggtggcctcctcaacggcaaagccgccgccgcc
gccaacccggcggcctcctccgctcagacccaccactccttcttgaactcgctggccgcc
ggctcccagttctccctcggccccatggtgacgaccgcctccgtgctgcagaccttgttc
aactcgatgccggccactggcctggtccccgtctcgtccgctgcgacccgcctctcaaac
gcgcacgcgatggggagcttctctccgggggttacaggtggaacagttggaggtattttt
aaccatgtggtgccttctgcctcctcctcctcctcctccttcactccttctccttccatt
tcctcttcctccttttcctcctcctcctcctcctcctctctcccctttggagcctccctg
ggccacggcgctggttccagctgtgccgtgctgagcttaacccctccgcaggtggcggcc
ggctctccctccttgcacgtgcccccccaccccccgccccccagcgacgcccagcatctc
agccgcgccaccgcgcccccctctctccgctcccctcctcccccgaatgtctccctcccg
cccccgcctcctctcctcgcgtctcactccgaacctgtcctcctgcagagcatgtcctcc
ctgccggccgccgaggccttcttgccaccctcctcctcctcctcctcctccaccaccgct
aactccgctttgtctcttaagctagcttctctccagcacaaaaccgcctgcccctccttt
actgtccaccacccgcctctgccccgcttggcgctggcgcaggccgcgcctgggatccca
cagtccaccgcagccggcccacccgccatgtgggtcaccctgggcatgcagtctccttac
gcttcgcacctctcgggggttaagccgcgataa
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