Hemicordylus capensis (graceful crag lizard): 128351621
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Entry
128351621 CDS
T08891
Symbol
PIK3CA
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
hcg
Hemicordylus capensis (graceful crag lizard)
Pathway
hcg00562
Inositol phosphate metabolism
hcg01100
Metabolic pathways
hcg04012
ErbB signaling pathway
hcg04068
FoxO signaling pathway
hcg04070
Phosphatidylinositol signaling system
hcg04081
Hormone signaling
hcg04140
Autophagy - animal
hcg04150
mTOR signaling pathway
hcg04210
Apoptosis
hcg04218
Cellular senescence
hcg04370
VEGF signaling pathway
hcg04510
Focal adhesion
hcg04620
Toll-like receptor signaling pathway
hcg04625
C-type lectin receptor signaling pathway
hcg04810
Regulation of actin cytoskeleton
hcg04910
Insulin signaling pathway
hcg04914
Progesterone-mediated oocyte maturation
hcg05100
Bacterial invasion of epithelial cells
hcg05132
Salmonella infection
hcg05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
hcg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
128351621 (PIK3CA)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
128351621 (PIK3CA)
04370 VEGF signaling pathway
128351621 (PIK3CA)
04068 FoxO signaling pathway
128351621 (PIK3CA)
04070 Phosphatidylinositol signaling system
128351621 (PIK3CA)
04150 mTOR signaling pathway
128351621 (PIK3CA)
09133 Signaling molecules and interaction
04081 Hormone signaling
128351621 (PIK3CA)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
128351621 (PIK3CA)
09143 Cell growth and death
04210 Apoptosis
128351621 (PIK3CA)
04218 Cellular senescence
128351621 (PIK3CA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
128351621 (PIK3CA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
128351621 (PIK3CA)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
128351621 (PIK3CA)
04625 C-type lectin receptor signaling pathway
128351621 (PIK3CA)
09152 Endocrine system
04910 Insulin signaling pathway
128351621 (PIK3CA)
04914 Progesterone-mediated oocyte maturation
128351621 (PIK3CA)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
128351621 (PIK3CA)
09171 Infectious disease: bacterial
05132 Salmonella infection
128351621 (PIK3CA)
05100 Bacterial invasion of epithelial cells
128351621 (PIK3CA)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hcg04131
]
128351621 (PIK3CA)
Enzymes [BR:
hcg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
128351621 (PIK3CA)
Membrane trafficking [BR:
hcg04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
128351621 (PIK3CA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_rbd
PI3K_p85B
DUF2321
ABC1
Retrotran_gag_4
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
128351621
NCBI-ProteinID:
XP_053167294
LinkDB
All DBs
Position
3:343156842..343242691
Genome browser
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVVLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESSPELPKH
IYNKLDKGHIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYAQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSHLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMYILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGGTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRPYCVHMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgcctccaagaccatcatctggtgaactgtggggcatccacttgatgccaccaagaatc
ctagtagagtgtcttctacccaatggtatgatagtggttttagaatgcctccgtgaggcc
accctgttaaatattaaacatgaactctttaaagaagctagaaaatatcctctctatcag
ctccttcaggatgagtcatcttacatttttgtaagtgttacacaagaagcagaaagagaa
gaattttttgatgaaacacggcggctatgtgatctgcgactcttccagccttttctaaaa
gtcatagagccagtaggcaacagagaagagaaaattctgaatcgagagattggttttgct
attggcatgcctatctgtgaatttgacttggttaaggatccagaagtacaggacttcaga
agaaacattcttaatgtttgtaaagaagcagtagatctgcgagatgctaatgcaccccat
agtagagcattatatgtatgtcccccaaacatagaatcttcgcccgagttgcccaaacat
atatacaataagctagataaagggcatataatagtggtgatatgggtaatagtctctccc
aacaatgacaagcaaaaatacaccttaaaaatcaaccatgattatgtgccagaacaagta
atcgctgaagcaatcaggaaaaaaacccgaagtatgttgctgtcaacggaacaactaaaa
ctctgtgttctagagtaccagggaaagtatattttaaaagtatgtggctgtgatgagtat
ttgttagaaaaacatccccttagtcagtataagtacatccggagttgtatcatgcttggg
cgaatgcccaacctgatgctgatggccaaggaaagtctttatgcccagctgccactggat
accttcacaatgccatcttattctaggcgtatctctacagctacaccatacatgaatgga
gaagcttctgccaaatccctctgggctattaacagtcatctccggataaggattctctgt
gctacctatgtaaatgtaaatattcgagacattgacaagatctatgtcagaactggtatc
taccatggaggagagccattatgtgataatgtgaatactcagagagtcccttgctccaat
cccagatggaatgaatggttgcagtatgagatgtacattcttgatcttccacgtgctgcc
cgactttgcctttctatctgctctgtcaaaggcagaaaaggtgcaaaggaggagcactgc
ccattggcgtgggggaatattaacatgtttgattacacagacactcttgtttctggcaaa
atggctctgaatctgtggcctgtacctcatggattggaagacctgttaaatcccattgga
ggcaccggatcaaatccaaataaggaaactccgtgtttagaattagaatttgattggttt
agcaatcctgtaaagtttcctgacatgacagtaattgaagaacatgccaattggactata
tctcgagaactaggatttaactacagtcatgctggactgagtaatagactagctagagat
aatgaattaagagagagtgataaagaacaactccgtgccatctgtactcgagaccccctg
tctgaaataactgaacaagaaaaggacttcctttggagccacaggccctattgtgtacat
atgcctgaaattctacccaagctgctcttgtctgttaaatggaactccagagatgaagta
gcccagatgtactgcttgataaaagactggcctcccatcaagcctgaacaggcaatggag
cttttggactgcaattacccagatccaatggtgcgagcatttgcagttcggtgtctggaa
aaatatttgacagatgacaaactttctcagtacttgattcaactggtacaggttctgaag
tacgagcagtacttggataatctgctggtgagatttttactcaagaaagcattgactaat
cagagaataggacacttcttcttttggcatctgaagtctgaaatgcacaacaaaaatgtg
agccagaggtttggtttgcttttggagtcctactgccgagcttgtgggatgtacctaaaa
catctgagcaggcaggtggaagctatggaaaaactgattaatctcacagacattctgaaa
caagagaaaaaggatgaaacgcaaaaggtacagatgaaattcctcgtggagcaaatgagg
cggccagacttcatggatgcattgcagggttttatatctcctcttaatcctgctcatcaa
cttggaacacttaggcttgaggagtgcaggattatgtcatctgcaaagaggccattgtgg
cttaactgggaaaacccagatattatgtctgaactgctgtttcagaacaatgagatcatc
tttaaaaatggggatgacctacgtcaggatatgctcacgcttcagatcattcgaattatg
gaaaacatctggcagaatcaaggcctggatcttaggatgctaccttacggttgtttatca
attggtgactgtgtggggctcattgaagttgtgagaaattcgcacacaatcatgcagatc
cagtgcaaaggtggccttaaaggcgcattgcagttcaacagtcacacgttacatcagtgg
ctcaaagacaagaacaaaggggaaatgtatgatgcagctattgacttgtttacacgctct
tgtgctggctactgtgtggctactttcatcttgggaattggggatcgtcacaatagtaat
ataatggtgaaagatgatggccagctgtttcatattgactttggacacttcttggatcac
aaaaagaaaaagtttggatacaaaagagaacgtgtgccatttgttctaacacaggatttc
ttgattgtgattagtaaaggagcccaagaatgtaccaaaacaagggaatttgaaaggttc
caggaaatgtgttacaaggcctatttagcaatccggcagcatgccaatctcttcataaac
ctcttctccatgatgcttggttcaggaatgcctgaattacagtcttttgatgacattgca
tatattcgaaaaactcttgcattggataagacagagcaggaagcactcgagtatttcatg
aaacagatgaatgatgctcatcatggtggttggacaacaaaaatggactggatcttccac
acaatcaagcaacatgccttgaactga
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