KEGG   Hemicordylus capensis (graceful crag lizard): 128351621
Entry
128351621         CDS       T08891                                 
Symbol
PIK3CA
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
hcg  Hemicordylus capensis (graceful crag lizard)
Pathway
hcg00562  Inositol phosphate metabolism
hcg01100  Metabolic pathways
hcg04012  ErbB signaling pathway
hcg04068  FoxO signaling pathway
hcg04070  Phosphatidylinositol signaling system
hcg04081  Hormone signaling
hcg04140  Autophagy - animal
hcg04150  mTOR signaling pathway
hcg04210  Apoptosis
hcg04218  Cellular senescence
hcg04370  VEGF signaling pathway
hcg04510  Focal adhesion
hcg04620  Toll-like receptor signaling pathway
hcg04625  C-type lectin receptor signaling pathway
hcg04810  Regulation of actin cytoskeleton
hcg04910  Insulin signaling pathway
hcg04914  Progesterone-mediated oocyte maturation
hcg05100  Bacterial invasion of epithelial cells
hcg05132  Salmonella infection
hcg05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:hcg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    128351621 (PIK3CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    128351621 (PIK3CA)
   04370 VEGF signaling pathway
    128351621 (PIK3CA)
   04068 FoxO signaling pathway
    128351621 (PIK3CA)
   04070 Phosphatidylinositol signaling system
    128351621 (PIK3CA)
   04150 mTOR signaling pathway
    128351621 (PIK3CA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    128351621 (PIK3CA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    128351621 (PIK3CA)
  09143 Cell growth and death
   04210 Apoptosis
    128351621 (PIK3CA)
   04218 Cellular senescence
    128351621 (PIK3CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    128351621 (PIK3CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    128351621 (PIK3CA)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    128351621 (PIK3CA)
   04625 C-type lectin receptor signaling pathway
    128351621 (PIK3CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    128351621 (PIK3CA)
   04914 Progesterone-mediated oocyte maturation
    128351621 (PIK3CA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    128351621 (PIK3CA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    128351621 (PIK3CA)
   05100 Bacterial invasion of epithelial cells
    128351621 (PIK3CA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hcg04131]
    128351621 (PIK3CA)
Enzymes [BR:hcg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     128351621 (PIK3CA)
Membrane trafficking [BR:hcg04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    128351621 (PIK3CA)
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B DUF2321 ABC1 Retrotran_gag_4 Ribosomal_S15
Other DBs
NCBI-GeneID: 128351621
NCBI-ProteinID: XP_053167294
LinkDB
Position
3:343156842..343242691
AA seq 1068 aa
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVVLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESSPELPKH
IYNKLDKGHIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYAQLPLD
TFTMPSYSRRISTATPYMNGEASAKSLWAINSHLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMYILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGGTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSHAGLSNRLARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRPYCVHMPEILPKLLLSVKWNSRDEVAQMYCLIKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctccaagaccatcatctggtgaactgtggggcatccacttgatgccaccaagaatc
ctagtagagtgtcttctacccaatggtatgatagtggttttagaatgcctccgtgaggcc
accctgttaaatattaaacatgaactctttaaagaagctagaaaatatcctctctatcag
ctccttcaggatgagtcatcttacatttttgtaagtgttacacaagaagcagaaagagaa
gaattttttgatgaaacacggcggctatgtgatctgcgactcttccagccttttctaaaa
gtcatagagccagtaggcaacagagaagagaaaattctgaatcgagagattggttttgct
attggcatgcctatctgtgaatttgacttggttaaggatccagaagtacaggacttcaga
agaaacattcttaatgtttgtaaagaagcagtagatctgcgagatgctaatgcaccccat
agtagagcattatatgtatgtcccccaaacatagaatcttcgcccgagttgcccaaacat
atatacaataagctagataaagggcatataatagtggtgatatgggtaatagtctctccc
aacaatgacaagcaaaaatacaccttaaaaatcaaccatgattatgtgccagaacaagta
atcgctgaagcaatcaggaaaaaaacccgaagtatgttgctgtcaacggaacaactaaaa
ctctgtgttctagagtaccagggaaagtatattttaaaagtatgtggctgtgatgagtat
ttgttagaaaaacatccccttagtcagtataagtacatccggagttgtatcatgcttggg
cgaatgcccaacctgatgctgatggccaaggaaagtctttatgcccagctgccactggat
accttcacaatgccatcttattctaggcgtatctctacagctacaccatacatgaatgga
gaagcttctgccaaatccctctgggctattaacagtcatctccggataaggattctctgt
gctacctatgtaaatgtaaatattcgagacattgacaagatctatgtcagaactggtatc
taccatggaggagagccattatgtgataatgtgaatactcagagagtcccttgctccaat
cccagatggaatgaatggttgcagtatgagatgtacattcttgatcttccacgtgctgcc
cgactttgcctttctatctgctctgtcaaaggcagaaaaggtgcaaaggaggagcactgc
ccattggcgtgggggaatattaacatgtttgattacacagacactcttgtttctggcaaa
atggctctgaatctgtggcctgtacctcatggattggaagacctgttaaatcccattgga
ggcaccggatcaaatccaaataaggaaactccgtgtttagaattagaatttgattggttt
agcaatcctgtaaagtttcctgacatgacagtaattgaagaacatgccaattggactata
tctcgagaactaggatttaactacagtcatgctggactgagtaatagactagctagagat
aatgaattaagagagagtgataaagaacaactccgtgccatctgtactcgagaccccctg
tctgaaataactgaacaagaaaaggacttcctttggagccacaggccctattgtgtacat
atgcctgaaattctacccaagctgctcttgtctgttaaatggaactccagagatgaagta
gcccagatgtactgcttgataaaagactggcctcccatcaagcctgaacaggcaatggag
cttttggactgcaattacccagatccaatggtgcgagcatttgcagttcggtgtctggaa
aaatatttgacagatgacaaactttctcagtacttgattcaactggtacaggttctgaag
tacgagcagtacttggataatctgctggtgagatttttactcaagaaagcattgactaat
cagagaataggacacttcttcttttggcatctgaagtctgaaatgcacaacaaaaatgtg
agccagaggtttggtttgcttttggagtcctactgccgagcttgtgggatgtacctaaaa
catctgagcaggcaggtggaagctatggaaaaactgattaatctcacagacattctgaaa
caagagaaaaaggatgaaacgcaaaaggtacagatgaaattcctcgtggagcaaatgagg
cggccagacttcatggatgcattgcagggttttatatctcctcttaatcctgctcatcaa
cttggaacacttaggcttgaggagtgcaggattatgtcatctgcaaagaggccattgtgg
cttaactgggaaaacccagatattatgtctgaactgctgtttcagaacaatgagatcatc
tttaaaaatggggatgacctacgtcaggatatgctcacgcttcagatcattcgaattatg
gaaaacatctggcagaatcaaggcctggatcttaggatgctaccttacggttgtttatca
attggtgactgtgtggggctcattgaagttgtgagaaattcgcacacaatcatgcagatc
cagtgcaaaggtggccttaaaggcgcattgcagttcaacagtcacacgttacatcagtgg
ctcaaagacaagaacaaaggggaaatgtatgatgcagctattgacttgtttacacgctct
tgtgctggctactgtgtggctactttcatcttgggaattggggatcgtcacaatagtaat
ataatggtgaaagatgatggccagctgtttcatattgactttggacacttcttggatcac
aaaaagaaaaagtttggatacaaaagagaacgtgtgccatttgttctaacacaggatttc
ttgattgtgattagtaaaggagcccaagaatgtaccaaaacaagggaatttgaaaggttc
caggaaatgtgttacaaggcctatttagcaatccggcagcatgccaatctcttcataaac
ctcttctccatgatgcttggttcaggaatgcctgaattacagtcttttgatgacattgca
tatattcgaaaaactcttgcattggataagacagagcaggaagcactcgagtatttcatg
aaacagatgaatgatgctcatcatggtggttggacaacaaaaatggactggatcttccac
acaatcaagcaacatgccttgaactga

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