Hydrogenimonas cancrithermarum: HCR_00040
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Entry
HCR_00040 CDS
T09533
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
hcj
Hydrogenimonas cancrithermarum
Pathway
hcj00290
Valine, leucine and isoleucine biosynthesis
hcj00660
C5-Branched dibasic acid metabolism
hcj01100
Metabolic pathways
hcj01110
Biosynthesis of secondary metabolites
hcj01210
2-Oxocarboxylic acid metabolism
hcj01230
Biosynthesis of amino acids
Module
hcj_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hcj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HCR_00040 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HCR_00040 (leuB)
Enzymes [BR:
hcj01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
HCR_00040 (leuB)
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Motif
Pfam:
Iso_dh
Thymidylate_kin
Motif
Other DBs
NCBI-ProteinID:
BDY11692
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All DBs
Position
3005..4072
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AA seq
355 aa
AA seq
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MRSYKIALIKGDGIGPEIIEEAVKVLDAVSFAEGFELKYEEYLLGGAAIDATGVPAPKET
LEGVKQADAVLFGAIGGEKWDNLPRDKRPETGLLKLRKELEVFANLRPVTVYDELINAST
LKPSVVQGVDLMVVRELIGGIYFGQPRGNDGQKAFNTMVYTKPEIVRIAKVAFEIAMKRS
KRVCSVDKANVLDVSQLWRDTVEAVAKDYPDVTLTHMYVDNAAMQLVRDPKQFDVILTGN
IFGDILSDEASMLSGSIGLLPSASIGEKYGLYEPIHGSAPDIAGQGIANPIATIASAAMM
LRYALNEEGAAERIERAIKHALHEGYRTQDLSAFDAKEVCSTSEIGSIIANYASK
NT seq
1068 nt
NT seq
+upstream
nt +downstream
nt
atgcgcagctacaagattgcacttatcaaaggtgacgggatcggccccgaaattatcgaa
gaggcggtcaaagtcctcgatgcggtgagctttgccgaagggttcgagctcaagtatgag
gagtatctgcttggcggtgccgcgatcgatgcgacaggcgttcctgcacccaaggagaca
ctcgagggcgtcaaacaggcggatgcggttcttttcggtgccatcggtggcgagaaatgg
gacaaccttccgcgcgacaaacgcccggaaaccgggcttttgaaactccgaaaagagctc
gaggtttttgcgaatcttcgtccggttacggtctatgacgagctgatcaacgcttccacg
ctaaaaccctccgttgtgcagggtgtcgatttgatggtcgttcgtgaactgatcggtggc
atctattttggccagccacgcgggaacgacgggcaaaaagccttcaatacgatggtttat
acgaagcccgagatcgtccgtatcgcgaaagtggctttcgaaatcgcgatgaaacgaagt
aaacgtgtctgttcggtcgacaaagccaacgttctcgacgtcagccagctctggcgcgat
acggtggaagcggtcgcgaaggactatccggatgttacactgacacatatgtacgtcgac
aacgcggcgatgcagctcgtgcgtgaccctaagcagttcgacgtcattttgacgggcaac
atcttcggagatattctcagcgacgaggcgagtatgctcagtggctccatcgggcttctt
ccttctgcatcgatcggtgaaaaatacggcctctacgagccgatccacggttcggcaccc
gacattgctgggcagggaatcgccaatccgatcgcgacgatcgcgagtgccgcgatgatg
ctgcgttacgctctcaatgaagagggtgccgccgagcggatcgagcgtgccatcaagcat
gcactgcacgaagggtaccgaacacaggatctgagcgcattcgatgccaaagaggtgtgc
tcgaccagcgagatcgggtcgatcatcgccaattacgcttcgaagtaa
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