Hydrogenimonas cancrithermarum: HCR_01860
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Entry
HCR_01860 CDS
T09533
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hcj
Hydrogenimonas cancrithermarum
Pathway
hcj00300
Lysine biosynthesis
hcj00550
Peptidoglycan biosynthesis
hcj01100
Metabolic pathways
hcj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hcj00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HCR_01860 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HCR_01860 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HCR_01860 (murF)
Enzymes [BR:
hcj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HCR_01860 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
BDY11874
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All DBs
Position
197799..199232
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AA seq
477 aa
AA seq
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MIWFQLFSHILLVMALGWYLATNLQWYSYKIERVILHHTRYVWHLIYFLIPLFAYYFTGI
YFWIYFYFAYLPTLWLWHRKLDKKLVLTGRIKRFFALLAMLTLFQDLLCLAKEACEVFGV
ILPLTMAVIGSMMIEKVLFHGFKLQAKRKLESMPDLIVIGVTASYGKTSIKNFIAQIVGH
EKRVYATPRSVNTLGGVMKDINDDLPEETEVYIVEMGARGPGDIAEITEFVQPHFAVVGV
IGPQHIEYFKTLERIRNTKMEILASKRLEHAWVHTSAHVEPDDRVTLFGDEIEHLEATLE
GVDFDLDLPQGKVHVHIPVLGAFNAVNVTAALHVANALGIPYEKGAEYAKSLEPVEHRLQ
RIDAGGKIILDDSFNGNVDGMLASFELVSQYPGRKVLVTPGLVESDIESNEKIAKRADEI
FDLVIVTGKINQPIFKRFVDGKKLHRLDDKSKMQEMLGALTRPGDLILFANDAPNFM
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgatctggtttcagctcttctcccatatcctgctggttatggcactggggtggtacctc
gcgaccaatctccagtggtacagttacaagatcgaacgtgtgatcctgcaccacaccagg
tatgtatggcatctcatctattttctgattccgctcttcgcctactactttaccggcatc
tatttctggatctatttctacttcgcctatcttccgactctctggctctggcacagaaaa
ctcgacaagaaactggtcctcaccgggcgtatcaagcgctttttcgcactccttgcgatg
ctcacgctctttcaggaccttctatgtctggcgaaagaggcgtgcgaggttttcggtgta
attttaccgctgacgatggcggtcataggttcgatgatgatcgagaaggtgcttttccac
ggcttcaaactccaggcaaaacggaaactcgaaagtatgcccgatctcatcgtaatcggt
gtgacggcgagctacggaaagaccagtatcaaaaacttcatcgcccagatcgtcgggcat
gagaagagagtctacgccacaccaagaagcgtcaatacgcttggtggcgtcatgaaagat
atcaacgacgatctgcccgaagagacggaagtctacatcgtcgagatgggcgcgcgcggc
ccgggcgacatcgccgaaatcaccgagttcgtccagccccacttcgccgtcgtcggtgtc
atcgggccgcagcatatcgagtacttcaaaacgctcgagcgcatccgcaacacgaagatg
gagatccttgcgagcaaacgtctcgagcatgcatgggtccacacatccgcccatgtcgaa
cccgacgatcgggtcaccctgtttggcgacgaaatcgaacatctcgaagcgaccctcgaa
ggcgtcgacttcgacctcgatctgccacagggaaaggtccatgtacacatccctgttctg
ggtgccttcaatgccgtcaacgtcactgccgcactacatgtcgcgaacgcattgggaatc
ccctacgaaaaaggggccgaatacgccaaaagcctcgaaccggtcgaacaccgcctccag
cgtatcgatgccggcggcaagatcattctcgacgatagcttcaacggcaatgtcgacgga
atgcttgcctccttcgagcttgtgtcgcagtatccggggcgtaaagtactcgtcacgccg
ggcctggtcgagagcgacatcgaatcgaacgagaagatcgcaaaacgggccgacgagatt
ttcgacctcgtcatcgtgacgggaaagatcaaccagccgatcttcaaaagattcgtggat
gggaagaaacttcatcgactggacgacaagtcgaaaatgcaggagatgctgggagcgttg
acacggccgggagacctgattctttttgccaacgacgcaccaaatttcatgtaa
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