Hippocampus comes (tiger tail seahorse): 109530852
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Entry
109530852 CDS
T04969
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
hcq
Hippocampus comes (tiger tail seahorse)
Brite
KEGG Orthology (KO) [BR:
hcq00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hcq01001
]
109530852 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hcq04131
]
109530852 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hcq04147
]
109530852 (lrrk2)
Enzymes [BR:
hcq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
109530852 (lrrk2)
Protein kinases [BR:
hcq01001
]
Serine/threonine kinases: TKL group
LRRK family
109530852 (lrrk2)
Membrane trafficking [BR:
hcq04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
109530852 (lrrk2)
Exosome [BR:
hcq04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
109530852 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
COR
Roc
Ras
LRR_14
LRR_1
Gtr1_RagA
MMR_HSR1
AAA_16
TFCD_C
AAA_22
NACHT
LRR_NXF1-5
Septin
nSTAND1
nSTAND3
Glyco_hydro127M
Viral_helicase1
Motif
Other DBs
NCBI-GeneID:
109530852
NCBI-ProteinID:
XP_019750324
LinkDB
All DBs
Position
Unknown
AA seq
2428 aa
AA seq
DB search
MRLLSQYHADSRVAIVALQALSLLLRSDAIALLLLEDEEEDVFGLVVRAMKAFPTGEEVQ
LQGCRALQALLHRVSDEHLVEFVENQDHLVVLAALHGFPGNPMLLLQAMKVLLPLSRPSS
NVEILMSGSARCYCALISAMDAFPQDEELQETACCLFRRFTSESYYNILVLNGVTRVAVR
ACRTFPCNATLQAAALSCLADLTSSMVQSRAAAEQGLEDGEAEENRGGSSEHVEDLDLDL
GWMGVCCTALDVHAADPHVQEAACWAIHSLLVHGAGRRHPEEEQDDRTPVHRQLMAAMLL
HSSSPSVFEAATSAIAMLVKQNPKMRSTLLSSGLHVNVAEMMKRHLASVQVSVSACRLLS
LLFQGRTAGLDELNMAVGQILSVMKFHNFQPEVQLEALRASLVFLCPDRSLREHGASVAD
PDMVDVSLKVLKNQCVVEGAHAVYLEVLNRFIRCPTIQVCGFKVLSALADCSGAVDLLCQ
QGAIDTVLHTLQMFPQDREIHYWGLTLLSFLVSKKKLSRMIVPVLASVLVASLGQYKEDY
DLLLKCFQVALRMLDACSGSAMELQREDFDRQIFQHLRESDIPEHGKNPLRRSACLALSK
MCANSELHYNMLEKACEDGDTVMAECLIELGADVNKKTKTESLIYQVCEKGGPLELVLLL
SQGAHEQHLRRALAVSVKRGDGPMVIQLLGRLGLDLNNNALCLGGFRLGRLDAAWLCPLL
AHRGRVHSLRYSSSSKGAGLARYIHSLQRSRTPGAPLKSLGDPCPTSGYISDESDDSSFS
FLSVDEGLFLDDMESDGSDSLTGVSLKPHNNSTEELRWGSFNRNHGRRRHASAESGPIDG
EHTEHAHRRYGRHPKTFGSLEISSALPKEKERIRLLDLSGNELDCLLCLMDHGPVQQQLA
HLLRLDLSHNVLLEFPPALCQSLSSLTRLDLQGNQLQSLPAELLALPALATLNVSRNCVG
PHLTFDASAACPSLRQLNLSFNKLTAFPCQLGRATQHLEELLLEGNNVADLLMPPPHLPE
LKLLDVSKNAVTDISPSFLTGCPKLEIFNASSNKIDSLEQLPAKLITLKLANNNFSVVSD
TILCLPNLRSVDMRTNHIAVLPGPGLWLSSNLRELMFSHNIIHELDLSGPVHNWSRLEKL
HLSNNKLTEIPPEVGLLEGLTSLDVSRNAGLRSFPDEMGRLGRLWDLPLDGLRLQLDLKL
IGSKTKDIVRFLQQRLKKAVPYYRMKLIVVGNAGSGKSSLVRKLMKLKRSQQASSRRMVG
TTVDVRDWTIKERDKKKMVLNVWDFSGGDEVCSSQPHFLSSRALYLVVHDLSRGAQQLDA
LKPWLFNIKAVAPFSPVILVGTHMDVSDDVAFQACLTKIREELLNHQGFPTIQNYFTVSA
CDDSDAVVRLRKAIAKEAADFKIQGQPVMGQLVPDSYVELERRLLQERTRVTKEFPVLTR
HQLLELIQESQLPLEEAELPHAIHFLSQAGVLLHFDDPTLQLQDLYFIDPQWLCNILLQK
LTLKDGVKHPQGVIERSSVENFLLEAKCFPSSHATHYLKLLEKFLIALPLGKDQLLVPNS
LSKDKPSIELPHCENSEVIVREYEMPYFPADFWPRQISRLLEVSAYLLYGREKVCPPEKV
CWNRGVHLSWSAEAYCLVEATWRQEEVSSVLRITVPSSRKGRVLLGQLVDQVDSLLEEWF
PGLLSTDVHGSGEALLKKWALYSFQDGHEWSKMLLEDLFTHFDQDFLLVNPEDPRCTVPI
SQVAPDAVLSDQPAWTILDSDELHVDLSKVNLLGDGGFGTVYRGVYKNEEVAVKLFNKHA
SELYIYRLLRQELVVLARLRHPSLVGLLAASSAPHVLVMELAMRGSLDSLFQHKKGSLNL
KLKHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFNLKTDADVIAKITDYGIAQYCCSMG
VRSSEGTPGFRAPEVARGNATYNQQADVFSFGLLLYDLLTGGERICDGVKFPSEFDEVAV
QGKLPDPVKHYGCSPWPGFQALMKDCLNVYPHDRPTSTQAFARLNSGEMLCLMRELPLPR
PVHAECVAVSAGTAWLGGGRSTQRTGTVTAVDLDSNRVTTQEIDSSPILCLVAVQIPGEA
SDWMVGGTQSGSLVVFSGVDPSTWYRLKNVSDAVTSLYFHVNPPRLQRKNYLLVGTADGL
LAIYEDSALKEFGQPVKSVVLGTVNTPVVCLGTSSYSLDRRCVWAGCGTRILSFSADYTV
SRNIDTRNTVPLPLRPSAEANVWRMAVDKYVYLSKAGMATVEVWDKWSERMVECIDCAQI
IRQECSADGGGPSGVADVPVDSSPSWARWARVKSLLVGQDSATLWVGTRGGHLLLLELGN
KHHALRVIPPRCHSLRGIASAFIETLNCKNAVLVLGRTLPQDKSEWDAQSVLMVWNATLP
SEVKDLNKHSERREHIAARMREQLHNYD
NT seq
7287 nt
NT seq
+upstream
nt +downstream
nt
atgagacttctgtcgcaataccacgcagatagccgggtggccattgttgcgctccaagct
ctgtccctccttctacgctcagatgccattgctctgctgctgctggaagacgaggaggag
gacgtgttcggcctagtggtgcgggccatgaaggctttccccaccggtgaggaggtgcag
ctccaaggctgtcgagctctgcaggcgctccttcatcgagtaagtgatgagcacctggtg
gagtttgtggagaaccaagaccacttggtggttctcgctgcactacatgggttccccggc
aacccaatgctgctacttcaggccatgaaggttctcctccccctgtcaagacccagcagt
aacgtggagatcttgatgtccggcagcgctcgctgctattgtgcgctcatctcggccatg
gacgccttcccgcaggatgaggagctccaggagacagcgtgctgcctgttccggagattc
acatcagagagctactacaacatcctggtgctgaacggcgtgacccgggtagcggtaagg
gcctgccggacgttcccctgcaacgccacgttacaggccgccgccctctcctgcctggca
gacctcacatccagcatggtgcagagtagagcggcggccgagcagggtttggaggacggc
gaggcggaggagaaccgcgggggcagctcggagcatgtggaggacttggacttagacctg
ggctggatgggggtctgctgcaccgcactggatgtccatgccgcagatccacatgttcag
gaagctgcatgctgggccattcacagtctgttggtgcacggagcaggaaggaggcatcca
gaagaggagcaggatgatcggactcctgttcacagacagctgatggcggccatgttgctt
cactcgtcctccccctccgtcttcgaggccgccaccagtgccatcgccatgctggtcaag
caaaatcctaagatgcgctccacgctgctgtccagcggcctccatgtcaatgtggcggag
atgatgaagaggcacctagcctcggtccaggtgtcggtcagcgcctgccgcctgctgagc
ctcctctttcagggccggacggccggcctggacgagctcaacatggccgtgggtcagatc
ctgagtgtcatgaagttccacaacttccagccggaggttcagctggaggccctgcgggcc
agcctggtcttcctctgtccagaccggagtttacgagagcacggcgcctcggtggcagac
cccgacatggtcgatgtgtccctgaaggtcctaaagaaccagtgtgtggtggagggagcg
catgcagtctacctggaggttctcaataggttcatcaggtgtccgaccatccaggtgtgc
ggctttaaggtgctctccgctctggctgactgctcaggtgcagtggacctgctctgccaa
caaggggccattgacacggtgctccacacgctgcagatgttcccgcaggatcgagaaatt
cactactggggtctgaccctgctcagcttcctggtgtccaagaagaagctctccaggatg
attgtccccgtcctggcctcagtcttggtggcctcactgggccagtacaaggaggattat
gacttgctgctcaagtgtttccaggtggcattgaggatgctggatgcctgttcaggatcg
gctatggagctgcagagggaagacttcgaccgtcagatattccagcacctccgagagtct
gacattcctgagcatggcaagaatccactccgtcggtcagcgtgtttggctctgtccaag
atgtgcgccaactcggagctgcactacaacatgctggagaaggcgtgtgaggacggagac
accgtcatggcagagtgcctcatcgagctcggggccgacgtcaacaagaagaccaaaacg
gagtcgctcatctaccaggtgtgcgagaagggaggcccgctagaactggtgctgctgttg
agccaaggtgcccacgaacagcacctgcgccgggcccttgccgtcagcgtgaagcgcggc
gacgggccgatggtcatccagctgctgggccgtctgggcctggacctcaacaacaacgcc
ttgtgtctcggtggttttcgcctcggccgactggacgccgcctggctctgccccctgctg
gcccaccgaggcagggtgcacagtctgcgctacagcagcagtagtaaaggagccggcttg
gcacgctacattcactccttgcagcgctccaggaccccgggagctcctctgaagtctctg
ggtgacccctgtccgacgtccggatacatctctgacgagagcgatgactccagcttcagt
ttcctctccgtggacgaaggcctcttcctcgacgacatggagagtgacgggagcgattca
ttgacgggggtctccctgaagccgcacaacaactccacagaggagctgaggtggggctcc
ttcaataggaaccatggacgccgccgacacgccagtgcggagagtgggccaattgatggc
gaacacactgaacatgcacacagacgatatggaaggcacccaaaaacgttcgggtctctg
gagatttcatcggcgcttcccaaggagaaggagaggatccgcctcctggacctgtcgggg
aacgagttagactgcctgttgtgcctgatggaccacgggccggttcagcagcagctggct
cacctcctgagactggacctgagccacaatgtcctgctggagtttccccctgcgctctgt
cagagtttaagcagcttgacccgactggacctgcagggcaatcagcttcagtcccttccg
gcggagctcctcgcgttgccggcgctcgccacgctcaacgtctcgcgcaactgcgtgggc
ccccacctcacctttgacgcttcggccgcctgtccgtccctgcggcagctcaacttgtcc
ttcaacaagctgaccgccttcccatgccagctggggcgggccacacagcacctcgaggag
ctgctgttggaagggaacaacgtggccgatctcctcatgcccccgccgcacctccccgag
ctcaaactgctggacgtgagcaagaacgccgtgacggacatctcgccaagctttctgacg
ggctgccccaagctggaaatcttcaacgcctcctccaacaaaatagattccttggaacag
ctcccagcaaagctcatcactctgaaacttgccaacaacaatttctccgtcgtttctgat
accatactctgcctgcctaacttgagatcagtggacatgagaaccaatcacattgcggta
ttaccgggcccgggcttgtggctgtccagtaacctgcgcgagttgatgttcagccacaac
atcatccacgagctggatttaagcggccccgtccacaactggagccgactggagaagctg
cacttgagcaacaacaagctcactgagatcccgccggaggtcggtctgctggagggtctc
acttctctggatgtgagccgcaacgccggactgcgctcctttcccgacgagatgggcagg
ctgggcagactttgggacctgccgctggacggcctgcgactccagctggaccttaaactg
atcggaagcaaaaccaaagacattgtcaggtttctgcagcagcgtctgaagaaggccgtt
ccctattaccggatgaagctcattgtggtggggaatgccggcagtgggaagagcagcctg
gtccgtaaactgatgaagctcaagcgctcgcagcaggcctcctccaggcggatggtcggc
accaccgtggacgtacgcgactggaccatcaaggagcgggacaagaagaagatggtgctg
aacgtctgggacttctccggtggcgacgaagtgtgcagctcgcagcctcatttcctgtcc
tccagagcactctacctggtggtgcacgacctaagcagaggagcccagcaactggacgcg
ctcaagccttggcttttcaacatcaaggcggtggctcctttctctccggtgatcctggtg
ggaactcacatggacgtgagcgatgacgtggcgttccaagcctgccttaccaagatccgc
gaggaactgctcaaccaccagggcttcccgaccatccagaactacttcaccgtgtcggcc
tgcgacgactcagatgccgtcgtccggctgcgcaaggccattgccaaggaggccgctgac
ttcaagatccagggtcagcccgtgatgggccagctggttcccgacagctacgtcgagctg
gaacgcaggcttctccaggagaggaccagggttacgaaggagttccccgtcctcacgcgc
caccagctgctggagctcatccaagagagtcagctgccgctggaggaggcggagcttccc
cacgccatccattttctcagccaagccggggtcttactgcactttgacgatcccaccctc
cagctccaggacctctacttcatcgacccgcagtggctctgcaacatcctcttgcagaaa
ctgaccctcaaggatggagtgaaacatccccaaggagtcattgagcgctcatccgtggaa
aactttctgctagaggccaaatgtttccccagcagtcatgccacgcactacttgaaactt
ctggagaaattcctgatcgcgctaccccttggaaaagaccagctgcttgtgcccaacagt
ttatcaaaagacaagccgagtattgagctgcctcactgcgagaactcggaggtgatcgtg
cgagaatacgagatgccgtacttccccgccgatttctggccacgacagatcagccgcttg
ctggaggtctccgcttatttgctttacgggagagagaaagtgtgtccacctgaaaaagtg
tgctggaaccgaggcgtgcacctcagctggtcggccgaggcctactgcctggtggaggca
acgtggcggcaggaagaagtctccagcgtgctacggatcaccgtgccgtcctcgcgcaaa
ggccgggtgctcctgggccagttggtggaccaggtggactccctgcttgaggagtggttc
ccgggcctgctgagcacggacgtgcatggcagcggcgaggcgctcctgaagaagtgggct
ctctacagcttccaggacggacacgagtggagcaagatgctgctggaggatctcttcacc
cacttcgaccaggactttcttctggtgaaccccgaggaccctcgctgcaccgttcccatc
tctcaggttgctccggatgcggtccttagcgaccagccggcttggaccatcctggacagt
gacgagctgcacgtggacctctccaaagtcaacctcctcggggacggcggctttggcacg
gtgtaccgaggcgtctacaagaacgaggaggtggctgtcaagttattcaacaagcatgcc
tcagaactttacatctacagactcctccgacaggagctggtggtgctggctcgcctgcgc
caccccagcctggtgggcctgctggcggccagctcggctccgcacgtccttgtgatggag
ctggccatgcggggctcacttgactccttgttccagcacaagaaaggaagcctaaatttg
aagctcaagcacaggatcgcgctgcacgtggccgacggattacggtacctccactcggcc
atgatcatctaccgcgacctgaagccccacaacgtgctcctgttcaacctcaagacggac
gcagacgtcatcgccaagatcaccgactacggcattgctcaatattgctgcagcatgggg
gtccgcagctcggagggcacgccaggtttccgcgcaccagaggtcgccagagggaacgcg
acgtacaaccagcaggccgacgtcttctcgttcggcctcctcctgtacgacctgctgacg
ggcggcgagcgcatctgtgacggcgtcaagttccccagcgagtttgacgaggtggccgtg
cagggcaagctgccagatccggtgaagcactacggttgctcgccttggcctggcttccaa
gccctgatgaaggactgtctaaacgtttatcctcatgatcgaccaacatccacgcaggcg
tttgcccggctcaactcgggggagatgttgtgtctgatgagggagctgccgctgcccagg
cccgtacatgccgagtgcgtggccgtaagcgctggcacggcctggctgggaggaggtcgc
agcacccagaggacgggaaccgtcaccgccgtggacctggactccaaccgggtcaccacg
caggagattgacagcagtcccatcctgtgcctggtggcggtccagattcccggcgaggct
tccgattggatggtcgggggcacacaatcgggctctctggtggtcttcagcggcgtggat
ccgtccacgtggtatcgcttgaaaaatgtctcagatgccgtcacctcgctgtactttcac
gtaaaccccccacgcctgcaacgaaagaactacttgctcgttggcactgcagatggcctt
ctcgccatctatgaagattccgccctcaaggagtttggtcagccggtgaaatcggtggtc
ctgggcaccgtcaacactcccgtggtgtgcttgggcacatcgtcgtactctctggaccgc
cgctgcgtttgggccggctgcggcaccaggatcctgtccttcagtgccgactacactgtg
agccggaacatcgacacccggaacaccgtaccactcccgcttcgccccagcgccgaggcc
aacgtgtggcgcatggcggtggataagtacgtgtacctcagcaaagccggcatggccacc
gtcgaggtttgggacaagtggagcgagcgcatggtggaatgcattgactgtgcacaaatc
atcagacaggagtgcagcgccgatggaggaggcccctccggtgttgcagacgtacccgtc
gacagctccccgtcttgggcccggtgggcgcgggtcaagtccctgctggttgggcaggat
tcggccacgctgtgggtgggcacccgaggcggccacctgctgcttctggagctgggcaac
aagcaccacgcgctgcgagtcatcccgccgagatgccactcgctacgaggcatcgcgtcg
gcgttcattgagacgctaaactgtaagaatgcggtgctggtgttgggcagaacactcccg
caggacaagagcgagtgggacgctcagtcggtgttgatggtgtggaacgccacgctgccc
tctgaggtcaaagacttgaacaaacacagtgagaggagagaacacattgcggccaggatg
agagaacagctacacaactatgactga
DBGET
integrated database retrieval system
