Candidatus Hamiltonella defensa (Acyrthosiphon pisum): HDEF_1900
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Entry
HDEF_1900 CDS
T00911
Symbol
thrA
Name
(GenBank) bifunctional: aspartokinase I (N-terminal); homoserine dehydrogenase I (C-terminal), threonine sensitive
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
hde
Candidatus Hamiltonella defensa (Acyrthosiphon pisum)
Pathway
hde00260
Glycine, serine and threonine metabolism
hde00261
Monobactam biosynthesis
hde00270
Cysteine and methionine metabolism
hde00300
Lysine biosynthesis
hde01100
Metabolic pathways
hde01110
Biosynthesis of secondary metabolites
hde01120
Microbial metabolism in diverse environments
hde01230
Biosynthesis of amino acids
Module
hde_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
hde00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HDEF_1900 (thrA)
00270 Cysteine and methionine metabolism
HDEF_1900 (thrA)
00300 Lysine biosynthesis
HDEF_1900 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
HDEF_1900 (thrA)
Enzymes [BR:
hde01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
HDEF_1900 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
HDEF_1900 (thrA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
ACQ68490
UniProt:
C4K7E7
LinkDB
All DBs
Position
complement(1738147..1740609)
Genome browser
AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANASQFLRVADIIECNRVHGQVAVVLSAPAKITDHLLTMIEIAFSGQSV
SQYLQQAESIFFDLLQGLNAAHPSLPYDPLKKMLQAEWTQIQQKLDGIALLGLCPDSVKA
SIICLGEKLSIAIMAAIFQAKEASITVINPVEKILAYGDYLESTVDIAESSLRISQMAIP
KDHVIFMAGFTAGNEKGECVLLGRNGSDYSAAVLAACLKADFCEIWTDVDGVYTCDPRLV
PDAKLLKSMSYQEAMELSYFGANVLHPRTIAPIAQFKIPCFIKNTSNPQAPGTLISHQQA
SDTEYPVKGITNLNHVAMINVSGPGMKGMTDIAARIFSVMSRKGISVILITQSSSEYSIS
FCIPGNKLLYARLALEEEFYLELKEGILDALDLMEDLAIISVIGDSMRTLRGICARFFSA
LARANINIIAIAQGSSERSISAVVKNEVATTGARVCHQMLFHTDQVMEVFIIGVGGVGSA
LIEQIRRQQSWLKHKQIDLRVCGIIDSKVMLTHLHGIDLNDWREQLAQAHTSSDLNRLTH
WVKEQRLLNPVIVDCTSSTLIANQYVTLLSNGFHVVTPNKKANTDSMAYYHELRKAAAQS
CRKFLYDTNVGAGLPVIENLQNLLNAGDELIQFSGILSGSLSFIFGKLDEGMTLSEATLD
AKQKGYTEPDPREDLSGMDVARKLLILAREAGYQLELDDIEVQSVLPANFDISGDVDTFL
KRLPSLDADFKQKASDARSQKKVLRYVGLIENQICKVRIEAVSSHDPLYKIKDGENALAF
YSRYYQPLPLVLRGYGAGNDVTAAGVFADLLRALSWKQDV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtcctgaaatttggtggaacctcagtagcaaatgcgtcgcaatttttacgcgtg
gccgatattatcgaatgtaaccgtgttcatggccaggtggcggtggtgctttctgccccc
gctaaaatcactgatcatcttttgaccatgattgaaatcgccttttctggtcagtctgtc
tctcaatatttacaacaagctgaaagcattttttttgatcttttacaggggctcaacgcg
gctcatccttcattgccttacgatccccttaaaaaaatgctacaggcagaatggactcag
attcaacaaaaattagatggaattgctttgctcggattgtgtcctgacagcgtgaaagcc
tctattatctgcctcggtgaaaaactctctattgctattatggccgctatttttcaggcc
aaagaggcgtctattactgtcattaatcctgtagaaaaaattttggcttacggggattat
cttgaatctactgttgatattgcagaatcctctttacgtatctctcaaatggcgattccg
aaagatcatgtaatttttatggccggttttactgcgggtaatgagaagggagaatgtgtt
ttgttgggtcgtaatggttcagattattctgccgcagtgttagccgcatgcttaaaagca
gatttttgcgaaatctggacggatgtggatggggtttatacttgtgatccccgtttggtt
cccgatgcaaaactgttgaaatcgatgtcctatcaagaagcgatggaattgtcttatttt
ggtgcgaatgtattacatccgcgtacaattgccccgattgctcaatttaaaattccttgc
ttcattaaaaatacgagcaatcctcaagcccctggtaccctaatcagccatcaacaagcc
agtgatactgaatatcctgttaaaggcattaccaacctcaatcatgtcgcgatgattaac
gtatctgggcctgggatgaaaggcatgaccgatattgccgccagaatattttcagtgatg
tcgcgtaaggggatctccgttattttgatcactcaatcttcttctgaatacagcatcagt
ttttgtatccctgggaacaaattattgtatgcacgcctggccttagaagaagaattctat
ttagaattaaaagaaggcattctcgatgcattagacctcatggaagatctggctatcatt
tctgtgattggagatagcatgcggaccttgcgaggcatttgcgcccgtttcttttcggct
ttagcgcgagcgaatattaatattattgcgattgctcagggctcttctgaacgttctatt
tctgctgtggtcaaaaacgaggtggcgaccaccggcgccagagtgtgtcaccaaatgctt
tttcataccgatcaagtcatggaagtttttattattggtgtcggtggggttggcagtgca
ttaatagaacagattcgtcgtcagcaatcctggctcaagcacaaacagattgatttgcgt
gtctgtgggatcatcgattcaaaagtcatgttaacgcatttgcatggtattgatttgaac
gattggcgggagcaattggcacaagcccacacttcgtctgacctcaatcggctgacgcat
tgggttaaagagcagcgtttattgaatcctgtcatcgtagattgcacttccagcacactc
atagcaaaccaatacgtgacattgctttcaaacggttttcatgtcgtcacacccaataaa
aaagccaatacggattctatggcctactatcatgaattaagaaaggcagccgctcaatcc
tgtcgcaaatttttatatgataccaatgtcggcgcggggctacctgtaattgaaaatttg
caaaatttgctcaatgccggcgatgagctgatccagttttctggcattttatcaggctct
ctttcttttattttcgggaagctcgatgaaggcatgaccctttcagaagcgacacttgac
gcaaaacagaaaggttatacggagcccgatcctcgagaagatttatcggggatggatgtg
gctcgcaagcttttaattttggcacgggaagcgggttaccagcttgagctagacgacatt
gaggttcagtcggtgttgcccgctaactttgatatttcaggggatgttgacacctttttg
aaacgtttgccttcattagatgcggattttaaacaaaaagcatcagacgccaggtcacaa
aaaaaggttttacgctatgttggattgattgaaaatcaaatctgtaaagtacgaatagaa
gcggtttccagccatgatcctctctataaaattaaagacggagaaaatgcacttgcattt
tacagtcgttactatcaacccttgcctttggtgttacgaggatatggcgctggtaatgat
gtcacggccgcgggggtttttgcggatttgttacgggccttatcctggaagcaggacgtt
taa
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