Hyphomicrobium denitrificans ATCC 51888: Hden_1397
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Entry
Hden_1397 CDS
T01265
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
hdn
Hyphomicrobium denitrificans ATCC 51888
Pathway
hdn00290
Valine, leucine and isoleucine biosynthesis
hdn00620
Pyruvate metabolism
hdn01100
Metabolic pathways
hdn01110
Biosynthesis of secondary metabolites
hdn01210
2-Oxocarboxylic acid metabolism
hdn01230
Biosynthesis of amino acids
Module
hdn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hdn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Hden_1397
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Hden_1397
Enzymes [BR:
hdn01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Hden_1397
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ADJ23209
UniProt:
D8JX73
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All DBs
Position
1447446..1449065
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AA seq
539 aa
AA seq
DB search
MSKERLYLFDTTLRDGAQTTGVDFSLEDKRRLMRVLDDLGVDYIEGGYPGANATDTELFT
SRPDLKSARFTAFGMTKRAGRSVSNDPGLQAILQSAADSICLVAKSSDYQVRVALGISKE
ENLDSVKQSVHAVVETQREAMIDCEHFFDGYKSNREYALAVARTAFDAGARWVVLCDTNG
GTLPHEIERIVSDVAKHVPGANLGIHTHNDTENAVANTLMAVRAGCRQIQGTLNGLGERC
GNANLTSIIPTLLLKSEFADAFATSVTPEKLRTLTHASRVLDEVLNEAPDRHAPYVGESA
FATKAGIHASALIKAPETYEHVPPESVGNERRILVSKQGGRSSLTAALERFGLPSDKDDA
RVQALLDEIKAREDQGYSYEAAEASFELLARRSLASVPRFFSVDSFRVTVERNRALNGSG
THAQAVVTVSIAGERDPLVSVGEGNGPVNALDKALRSDLGRYQKHIDHVELVDYKVRILT
QTQSGGTDAVTRVLVESHDTETGERWTTVGVSTNIIDASFEALLDSINYKLLKDDARAA
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atgagcaaagagcgcctctatcttttcgacacgacgctgcgcgacggtgcgcagacgacg
ggcgtcgatttttcgctcgaggataagcggcgtttgatgcgcgtgctcgatgatctcggc
gtcgattacatcgagggcggctatcccggcgcgaacgcgaccgatacggagcttttcacg
tcgcggccggacctgaagtcggcgcggttcacggcattcggaatgaccaagcgggccggg
cgttcggtgtcgaacgatccgggcctgcaggcgattctgcagtcggcggccgacagcatc
tgcctcgtcgcgaagtcgtccgactatcaggtgcgcgtcgcgctcggcatctcgaaggaa
gaaaatctcgactccgtcaagcaatcggtccacgccgtcgtcgagacgcagcgcgaggcg
atgatcgactgcgagcattttttcgacggctacaaaagcaatcgcgagtacgcgctcgcc
gttgcgagaaccgcctttgacgcgggcgcgcgctgggtcgttctctgcgacacgaacggc
ggaacgctgccgcacgaaatcgagcgcatcgtcagcgacgtcgcaaagcacgtgccgggc
gcgaacctcggcatccatacgcacaacgataccgagaacgccgtcgccaatacgctgatg
gcggtgcgcgccggatgccgacagatccagggaacgctcaacggtcttggcgagcgctgt
ggcaacgccaatctgacctcgatcattccgacgctgctgttgaagagcgaattcgccgat
gccttcgcgaccagcgtcacgcctgagaagcttcggacattgacgcacgccagccgcgtg
ctcgacgaagttctgaacgaggcgccggaccggcatgcgccttacgtcggtgaaagcgcg
ttcgcgacgaaggccggaattcatgcatcggcgctgatcaaggcgcccgaaacctacgag
cacgtgccgcctgaaagcgtcggcaacgaacggcgcatcctggtgtcgaagcagggcggt
cggtcgtcgctcaccgccgcgctcgagcgctttggattgccgtccgacaaggacgatgcg
cgcgtgcaggcgctgctcgatgagatcaaggcgcgcgaggatcagggctattcctacgag
gctgcggaagcttcgttcgaactgctggcgcggcgttcgctcgccagcgtgccgcggttc
ttttccgtcgactcattccgcgtgaccgtcgaacgcaaccgggcgctgaacggcagcggc
acgcatgctcaggcggtcgtaacggtgtcgatcgctggcgaacgcgatccgctcgtttcg
gtcggcgagggcaacggtccggtcaacgccctcgacaaggcgttacgtagtgatctcggc
cgctaccagaagcacatcgatcacgtcgaactcgtcgactacaaggttcgcatcctgacg
caaacgcagagtggcggcacggatgccgtgacgcgcgtgctcgtcgaaagccacgacact
gaaaccggcgagcgctggacgacggtcggcgtgtccacgaacatcatcgatgcgagcttc
gaggcgcttctcgacagcatcaattacaagctgctgaaagacgacgcgcgcgccgcctga
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