KEGG   Halomonas elongata: HELO_1726
Entry
HELO_1726         CDS       T01311                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
hel  Halomonas elongata
Pathway
hel00290  Valine, leucine and isoleucine biosynthesis
hel00620  Pyruvate metabolism
hel01100  Metabolic pathways
hel01110  Biosynthesis of secondary metabolites
hel01210  2-Oxocarboxylic acid metabolism
hel01230  Biosynthesis of amino acids
Module
hel_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:hel00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    HELO_1726 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    HELO_1726 (leuA)
Enzymes [BR:hel01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     HELO_1726 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: CBV41610
UniProt: E1V847
LinkDB
Position
845372..847078
AA seq 568 aa
MMLDNPSTKYRPFVAVDLPDRQWPNRRIETPPQWCAVDLRDGNQALIDPMDQERKQRFFD
LLVKIGFKQIEVGFPSASQTDFDFVRSLIEDDKVPDDVTIQVLTQARPHLIDRTFEALKG
AKNAIVHVYNATDPVFRRVVFNVDKAECIQIAVDATTRIREHMAAAPETNWTFQYSPELF
STTEMDFAVQIVDKVSETFGPTVEAPMIVNLPATVECATPNNYADQIEWFCRHVAQRDCL
IVSVHPHNDRGTGVAAAELAVMAGADRVEGCLFGNGERTGNVDLVTLAMNLYTQGVHPGL
DFSNITPIMREVEYCNQLPVHPRHPYVGDLVFTAFSGSHQDAIKKGMAARREDPDGVWAV
PYLPIDPLDVGRSYEAVIRVNSQSGKGGVSYLLEQEHGIELPRRLSIEFSQVVQEVADRL
GREITSEMIYQAFRDEYLEKDRPFALASHRMSSEPDSPVVNLEATIEEDGARRTIQGQGN
GPLAAFIKSLAAEGHDVEIIDYHEHSRGQGADAEAIAYVEVRINGEAVFGVGTDESITSA
SIKGVLSAINRQLSTEAPAPNVTAETLA
NT seq 1707 nt   +upstreamnt  +downstreamnt
atgatgctcgataacccctccaccaagtaccgccccttcgtggccgtcgatctgccggac
cggcagtggcccaaccggcgcatcgagacgccaccccagtggtgcgccgtcgatctgcgc
gacggcaatcaggcgctcatcgatccgatggatcaggagcgcaagcagcgcttcttcgac
ctgctggtgaagatcggcttcaagcagatcgaggtgggctttccctcggcgtcgcagacc
gacttcgacttcgtgcgttcgttgatcgaggacgacaaagttccggacgacgtcaccatc
caggtgctgacccaggcgcgcccgcatctcatcgatcgcaccttcgaggctctgaagggc
gccaagaacgccatcgtccacgtctacaatgccaccgacccggtgttccgccgcgtggta
ttcaacgtcgacaaggccgagtgcatccagatcgccgtggacgccacgacacgcatccgc
gagcacatggcggcggcaccggagaccaactggaccttccagtactctccggaactgttc
tccaccaccgagatggatttcgcggtgcagatcgtcgacaaggtcagcgagacgttcggc
cccaccgtcgaggcgccgatgatcgtcaacctgccggccaccgtggagtgcgcgaccccc
aacaactatgccgaccagatcgaatggttctgccgccacgtcgctcagcgcgattgcctg
atcgtcagtgttcacccgcacaacgaccgggggaccggcgtcgccgcggccgagcttgcc
gtgatggccggtgccgaccgtgtcgagggctgcctgttcggtaacggcgagcgcaccggc
aatgtcgacctcgtcaccctggccatgaacctctatacccagggcgttcacccggggctc
gatttctccaacatcacgccgatcatgcgtgaggtggaatactgcaaccagctgccggtg
catccgcgtcatccctatgtcggcgacctggtgttcaccgccttctccggctcccaccag
gacgccatcaagaagggcatggcggcacgtcgcgaggaccccgatggcgtctgggcggtg
ccctatctgcccatcgatccgctggacgtcgggcgcagctatgaggcggtgattcgcgtc
aacagccagtccggcaagggcggtgtgtcctatctgctggaacaggagcacggcatcgag
ctgccgcgtcggctgtccatcgaattcagccaggtggtccaggaagtcgccgaccggctg
ggccgcgagatcacgtccgagatgatctatcaggccttccgcgacgagtacctggagaag
gaccggcccttcgccctggccagccatcgcatgtcctcggagcccgacagcccggtggtg
aatctcgaggcgaccatcgaggaagatggagcccggcggaccatccaggggcagggcaac
ggcccgctggccgccttcatcaagtcgctggccgccgaagggcatgacgtggaaatcatc
gattaccacgaacattcccgggggcagggggccgacgccgaggcgatcgcctatgtcgag
gtacgcatcaacggcgaggccgtattcggggtcggcaccgatgaaagcatcaccagcgcc
tcgatcaagggcgtgctgagcgccatcaaccggcaactctccaccgaagcgccagcgccc
aacgtcaccgccgaaaccctggcctga

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