Helicobacter pylori SouthAfrica7: HPSA_03540
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Entry
HPSA_03540 CDS
T01921
Name
(GenBank) D-alanyl-D-alanine-adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hes
Helicobacter pylori SouthAfrica7
Pathway
hes00300
Lysine biosynthesis
hes00550
Peptidoglycan biosynthesis
hes01100
Metabolic pathways
hes01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hes00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HPSA_03540
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HPSA_03540
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HPSA_03540
Enzymes [BR:
hes01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HPSA_03540
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ADU84707
UniProt:
E8QRU3
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All DBs
Position
725753..727234
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AA seq
493 aa
AA seq
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MQSPSWLDLAFRWLFVTGLGYYVMTLLQWYHYSVFRILTKHHKTRWHGIYFVLPLGVFIL
SYAFKMPFVFDFFCGVIQIPMLVIWAKRNDKPLVFTPRVKRFFIFLLLFLILHEILNIEL
VSLSGISLALGYLCLFVFVLSASLIFEKVLSKQYLQIAKDKIASLKNLKVIAITGSFGKT
STKNFLHQILQTTFNVHASPKSVNTLLGIASDINQNLEDSSEIYIAEAGARNKGDIKDIT
RLIEPHLAVIAEVGEQHLEYFKTLENICETKAELLDSKRLENAFCYSVEKIKPYAPNNAP
LIDYSSLVKNIQSTLKGTSFEMLLDGVWENFETKVLGKFNAYNIALAILIAKHLGLETER
IKRLVLDLNPIAHRLQLLEVNQKVIIDDSFNGNLKGMLEGIRLASLYEGRKVIVTPGLVE
SNTESNEILAEKINEVFDVAIITGELNSKTIASHLKKPQKILLKDKGQLENILQATTIQG
DLILFANDAPNYI
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcaaagtcctagttggctggatttagcgtttcgttggctctttgtaacagggcttggc
tattatgtgatgactttattgcaatggtatcattacagcgtgtttaggatcttaaccaag
caccataaaacacgctggcatgggatttattttgtgttgcctttaggggtgtttatccta
tcgtatgctttcaaaatgccgtttgtttttgatttcttttgcggcgttattcaaataccc
atgctcgttatttgggctaagcgcaacgacaagcctttagttttcacgccaagggtgaag
cgcttttttatttttttattgctatttttaatcttgcatgaaatcttaaacatagaatta
gtttctttaagcgggatctcgctcgcgctgggttatttgtgtttattcgtgttcgtttta
agcgcttctttaatctttgaaaaagtcttatccaagcagtatttgcaaatcgctaaagat
aaaatcgcctctttaaaaaatctaaaagtcatcgccattaccgggagttttgggaaaacc
agcaccaaaaatttcttgcatcaaatcttgcaaaccacattcaatgtgcatgcaagccct
aaaagcgtcaacacccttttaggcattgcaagcgacattaaccaaaatttagaagatagt
agcgaaatttatatcgctgaagccggggcaaggaataaaggcgatattaaagacatcacc
cgccttattgaaccgcaccttgctgtgatcgcagaagtgggcgaacagcatttagaatat
tttaaaactttagaaaatatttgcgagactaaagcggaattattggattcaaaacgctta
gaaaacgccttttgttactctgtagaaaaaatcaaaccctatgcccctaataacgcccct
ttaatagattattctagcctggttaaaaacatccaatccactttaaaaggcacttctttt
gaaatgcttttagatggcgtttgggaaaattttgaaacgaaagttttaggcaaatttaac
gcttataatatcgctttagctattttaatcgccaaacatttaggtttagaaacagaaagg
atcaaacggcttgtgttggatctcaaccctattgcccatcgtttgcaacttttggaagtg
aatcaaaaagtcattatagacgatagctttaatgggaatttaaaaggcatgttagagggc
attcgtttagcgagtttgtatgaagggcgtaaagtcattgtaacgccaggattagtggaa
agcaatacagaaagcaatgaaattttagcggaaaaaatcaatgaagtctttgatgtcgct
atcatcacaggggagttgaattctaaaacgattgcttcccatttaaagaaacctcaaaaa
atcctactcaaagataaggggcaattagaaaatatcttgcaagccactacgattcaaggc
gatttgattttatttgctaatgacgcccccaattacatttaa
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