Helicobacter pylori Puno135: HPPN135_03645
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Entry
HPPN135_03645 CDS
T01920
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; putative membrane protein
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
heu
Helicobacter pylori Puno135
Pathway
heu00300
Lysine biosynthesis
heu00550
Peptidoglycan biosynthesis
heu01100
Metabolic pathways
heu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
heu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HPPN135_03645
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HPPN135_03645
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HPPN135_03645
Enzymes [BR:
heu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HPPN135_03645
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF7217
Motif
Other DBs
NCBI-ProteinID:
AEN18423
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Position
744730..746211
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AA seq
493 aa
AA seq
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MQSLSWLNLAFRWLFITGLGYYIMTLLQWYHYSVFRILTKHHKMRWHGIYFLLPLGVFIL
SYAFTMPFVFDFFCGVIQMPMLIVWAKRNDKPLVFTPRVKRFFIFLLLFLILHEILNTEL
VPLNGISLALGYLCLFMFVLSASLIFEKVLSKQYLQTAKDKIASLKNLKVIAITGSFGKT
SIKNFLLQILQTTFNAHASPKSVNTLLGLANDINQNLDDRSEIYIAEAGARNKGDIKEIT
RLIEPHLAVVAEVGEQHLEYFKTLENICETKAELLDSKRLEKAFCYSVEKIKPYAPKDSP
LTDYSSLVKNIQSTLKGTSFEMLIGSVWESFETKVLGKFNAYNIASAILIAKHLGLETER
IKRLVLELNPIAHRLQLLEVNQKIIIDDSFNGNLKGMLEGIRLASLYEGRKVIVTPGLVE
SNTESNETLAQKIDEVFDVAIITGELNSKTIASQLKTPQKILLKDKAQLENILQATTIQG
DLILFANDTPNYI
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcaaagtcttagttggctgaatttagcgtttcgttggctctttataacagggcttggc
tattatataatgactttattgcaatggtatcattacagcgtgtttaggatcttaaccaag
caccacaaaatgcgttggcatgggatttattttttattgcctttgggggtgtttatcctg
tcgtatgctttcacaatgccgtttgtttttgatttcttttgtggcgttattcaaatgccc
atgctcattgtttgggccaaacgcaacgacaaacctttagttttcacgccaagggtgaag
cgcttttttatcttcttattgttatttttaatcttgcatgaaatcttaaatacagaatta
gtccctttgaatgggatttcgctcgcactaggctatttgtgtttattcatgtttgtttta
agcgcttctttaatctttgaaaaggtcttatccaagcagtatttgcaaaccgctaaagat
aaaatcgcctctttaaagaatttaaaagtcatcgccattactggaagctttgggaaaacc
agcattaaaaatttcttgcttcaaatcttacaaaccacattcaacgcgcatgcaagcccc
aaaagcgtcaatacccttttagggcttgcgaatgatattaaccagaatttagatgatagg
agtgaaatctatatcgctgaagccggggcaaggaataagggcgatattaaagaaatcacc
cgcctcattgaaccgcaccttgccgtggtcgcagaagtgggcgaacagcatttagaatat
tttaaaactttagaaaatatttgcgagactaaagcggaattattggattccaaacgctta
gaaaaagccttttgttactctgtagaaaaaatcaagccctatgccccaaaagatagccct
ttaacagactattctagcctggttaaaaacatccaatccactttaaaaggcacttctttt
gaaatgcttataggtagcgtttgggaaagctttgaaacaaaggttttaggcaaattcaac
gcttataatatcgcttcagccattttaatcgctaagcatttaggcttagagacagaaagg
atcaaacggcttgttttagaactcaaccctattgcccatcgtttgcaacttttggaagtg
aatcaaaaaatcattatagacgatagttttaatgggaatttaaagggcatgttagagggc
attcgtttagcgagtttgtatgaagggcgtaaagtcattgtaacaccgggattagtggaa
agcaatacagaaagtaatgaaactttagcgcaaaaaatagatgaggtttttgatgtcgct
atcatcacaggggagttgaattccaaaacgattgcttcacaactaaaaaccccccaaaaa
atcttactcaaggataaggcgcaattggaaaatatcttacaagccaccacgattcaaggc
gatttgattttattcgctaatgacacccctaattacatttag
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