Helicobacter pylori BM012S: U064_1048
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Entry
U064_1048 CDS
T02940
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hez
Helicobacter pylori BM012S
Pathway
hez00300
Lysine biosynthesis
hez00550
Peptidoglycan biosynthesis
hez01100
Metabolic pathways
hez01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hez00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
U064_1048
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
U064_1048
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
U064_1048
Enzymes [BR:
hez01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
U064_1048
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AHA89963
UniProt:
V5NP50
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All DBs
Position
1069394..1070875
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AA seq
493 aa
AA seq
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MQSLSWLNLAFRWLFITGLGYYIMTLLQWYHYSVFRILTKHHKMRWHGIYFLLPLGVFIL
SYAFKMLFVFDFFCGVIQMPMLIVWAKRNDKPLVFTPRVKRFFIFLLLFLILHEILNTEL
VPLSGISLALGYLCLFIFVLSASLIFEKVLSKQYLQTAKDKIVSLKNLKVIAITGSFGKT
STKNFLLQILQTTFNAHASPKSVNTLLGLANDINQNLDDRSEIYIAEAGARNKGDIKEIT
RLIEPHLVVVAEVGEQHLEYFKTLENICETKAELLDSKRLEKAFCYSVEKIKPYAPKDSP
LIDVSSLVKNIQSTLKGTSFEVLLDSVWESFETKVLGKFNAYNIASAILIAKHLGLETER
IKRLVLELNPIAHRLQLLEVNQKIIIDDSFNGNLKGMLEGIRLASLHEGRKVIVTPGLVE
SNTESNETLAQKIDGVFDVAIITGELNSKTIASQLKTPQKILLKDKAQLENILQATTIQG
DLILFANDAPNYI
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcaaagtcttagttggctgaatttagcgtttcgttggctctttataacagggcttggc
tattatataatgactttattgcaatggtatcattacagcgtgtttaggatcttaaccaag
caccacaaaatgcgttggcatgggatttattttttattgcctttaggggtgtttatccta
tcgtatgctttcaaaatgctgtttgtttttgatttcttttgcggcgttattcaaatgccc
atgctcattgtttgggccaaacgcaacgacaagcccttagttttcacgccaagggtgaag
cgcttttttatcttcttattattatttttaatcttgcatgaaatcttaaatacagaatta
gtccccttgagtgggatttcactcgcgctaggctatttgtgtttgtttatattcgtttta
agcgcttctttaatctttgaaaaagtcttatccaagcagtatttgcaaaccgctaaagat
aaaatcgtctctttaaagaatttaaaagtcatcgccattaccggaagctttgggaaaacc
agcaccaaaaatttcttgcttcaaatcttacaaaccacattcaacgcgcatgcaagcccc
aaaagcgtcaatacccttttagggcttgcgaatgatattaaccagaatttagatgatagg
agtgaaatctatatcgctgaagccggggcaaggaataagggcgatattaaagaaatcacc
cgcctcattgaaccgcaccttgttgtggtcgcagaagtaggcgaacagcatttagaatat
tttaaaactttagaaaatatttgcgagactaaagcggaattgttggattccaaacgctta
gaaaaagccttttgttactctgtggaaaagatcaagccctatgcccctaaagatagtcct
ttaatagatgtttctagcctggttaaaaacatccaatccactttaaaaggcacttctttt
gaagtgcttttagatagcgtttgggaaagctttgaaacgaaggttttaggcaaatttaac
gcttataatatcgcttcagccattttaatcgctaaacatttaggcttagaaaccgaaagg
atcaaacggcttgttttggaactcaaccctatcgcccatcgtttgcaacttttggaagtg
aatcaaaaaatcatcatagacgatagctttaatgggaatttaaagggcatgttagaaggc
attcgtttagcgagtttacatgaagggcgtaaagtcattgtaacaccgggcttagtggaa
agcaatacagaaagtaatgagactttagcgcaaaaaatagacggggtttttgatgtcgct
atcatcacaggggagttgaactccaaaacgattgcttcacaattgaaaacccctcaaaaa
atcttactcaaggataaggcgcaattggaaaatatcttacaagccaccacgattcaaggc
gatttgattttattcgctaatgacgcccctaattacatttag
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