Candidatus Hydrogenisulfobacillus filiaventi: R50_0812
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Entry
R50_0812 CDS
T08923
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
hfv
Candidatus Hydrogenisulfobacillus filiaventi
Pathway
hfv00290
Valine, leucine and isoleucine biosynthesis
hfv00620
Pyruvate metabolism
hfv01100
Metabolic pathways
hfv01110
Biosynthesis of secondary metabolites
hfv01210
2-Oxocarboxylic acid metabolism
hfv01230
Biosynthesis of amino acids
Module
hfv_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hfv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
R50_0812 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
R50_0812 (leuA)
Enzymes [BR:
hfv01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
R50_0812 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
HCS_D2
LeuA_dimer
Rpf1_C
DUF7108
Motif
Other DBs
NCBI-ProteinID:
CAB1128318
UniProt:
A0A6F8ZEM4
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All DBs
Position
1:767960..769498
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AA seq
512 aa
AA seq
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MSEDFVRIFDTTLRDGEQSPGVALTAKAKVTIAEQLARLNVDIIEAGFPAASEGDFAAVK
AIAETVRGPVIAGLARCLPGDIEVAAAAVEKAERARIHVFIATSPLHMQAKLRMEPEQVL
EQADKMVRLARSYVDDVEFSAEDATRSELDFLIRIATLAVKAGARTINIPDTVGYTTPDE
FGAMVAAVRQAVAAIDPGVIVSVHCHNDIGLAVANSLAGVQAGARQVEVAVNGIGERAGN
AALEEVVMALTNRRDHYGIATHIVTREIYRTSQMVSRMTGMLVQPNKAVVGLNAFRHEAG
IHQDGMLKNRQTYEVLRPEDIGVPESLLVLGKHSGRHALRQRLNDLQLKCTEEELARIQA
QVKSLAEIKNEINDADLEAIWADVVLGVHEPDIHLEHWQVSTGNDMRPTAQVSVRIHDRV
FEDAGFGDGPVHALFNALRRALDLGDAEMRSYTLSPISPGEDGLATVRVEIAARGLTSRG
QGTASDVLAASVEAMTAAMGQLLTRVRGPVVA
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atgtcggaggatttcgtccgcatctttgacaccaccctgcgcgacggggagcagtcgccg
ggggtggccctgaccgccaaggccaaggtgacgatcgcggaacagctggcgcggctcaat
gtcgacatcatcgaagccggcttccccgccgcctccgaaggggactttgcggcggtgaag
gcgattgcggagacggtgcggggaccggtcattgccggcctggcccgctgcctgcccggg
gacatcgaagtggccgcggcggcggtggagaaggcggagcgggcccgcatccatgtgttc
atcgccacctcgcccctgcacatgcaggccaagctgcgcatggagcccgagcaggtgctg
gagcaggcggacaagatggtgcggctggcgcgcagctacgtggatgatgtggaattctcg
gccgaggacgccacccgcagcgagctggacttcctcatccgcatcgccaccctggccgtg
aaggcgggggcgcggaccatcaacatccccgacaccgtgggctacaccactcccgacgag
ttcggcgccatggtggctgcggtccgccaggcggtggccgccatcgaccccggggtcatc
gtctcggtgcactgccacaacgacatcggcttggcggtggccaactccctggcgggggtg
caggcgggggcgcgccaggtggaggtggcggtcaacggcatcggcgagcgggccgggaat
gccgccttggaggaggtggtgatggccctcaccaaccgccgcgaccattacgggatcgcc
acccacatcgtcacccgggagatctaccgcaccagccagatggtctcccgcatgacgggc
atgctggtgcagcccaacaaggcggtggtgggcctcaacgccttccgccacgaggccggc
atccaccaggacggcatgctgaagaaccgccagacctacgaggtgctgcggccggaggac
atcggggtgccggagtcgctgctggtgctgggcaagcactcgggacggcacgccctgcgg
cagcgcctcaatgacctgcagctgaagtgcaccgaggaggagctggcgcggattcaggcc
caggtcaagagcctggccgagatcaagaacgagatcaacgacgccgacctcgaggccatc
tgggcggacgtggtgctgggggtgcacgagccggacatccacctggagcattggcaggtg
tccaccggcaacgatatgcggcccacggcccaggtctcggtccgcatccacgaccgcgtg
ttcgaggatgccggcttcggggacggccccgtgcacgctctcttcaacgccctgcggcgg
gcgctggacctcggggatgcggagatgcgctcctacaccctctcccccatttcgccgggg
gaggacgggctggccacggtgcgggtggagatcgccgcccgcggcctgaccagtcggggc
cagggcacggcctccgatgtgctggcggcgtcggtggaggccatgacggccgccatgggg
cagctgctcacccgcgtgcgcggcccggtggtagcctag
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