Candidatus Hydrogenisulfobacillus filiaventi: R50_2189
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Entry
R50_2189 CDS
T08923
Name
(GenBank) Dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
hfv
Candidatus Hydrogenisulfobacillus filiaventi
Pathway
hfv00790
Folate biosynthesis
hfv01100
Metabolic pathways
hfv01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
hfv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
R50_2189
Enzymes [BR:
hfv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
R50_2189
6.3.2.17 tetrahydrofolate synthase
R50_2189
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
CAB1129686
UniProt:
A0A6F8ZIT4
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Position
1:complement(2005340..2006632)
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AA seq
430 aa
AA seq
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MKETWWGGREPNRIKPGLERMQALMERLGHPERACPVIHVAGTNGKGSTVAMIAAALRGQ
GWRVGMTVSPDLGAINQRVQIGERPLEPRLWDLLGAEVEEAGAGLADVPSFFEAVTALAF
LAFRRLAVDVAVVEVGLGGRWDATNVVPPPLLTVITPIAFDHMDRLGHTITAIAGEKAGI
LKPGSRLVLAGQPYPEAAAVVRARAAEAGVPVREAVAWPGGSDQEGTYLQFPDGSTVRVP
LLGAYQLDNLRTAWTAVEELAAAGWADPGRAREALSTVEWPGRFEVVSRDPLIVLDGAHN
LHGAAGLARSLRQPPWAGRRWQLVFAALNDKPALAMATALAPLAAGVVVTRVPGERGTDP
AAVAAGLRERGFTVPISVEPDPLQAVARARERLGPGEGLLVTGSLALMAGLKAQGLPGPQ
DSAAFRRASG
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
ttgaaggagacctggtggggcggccgcgagcccaaccgcatcaagcccgggctggagcgt
atgcaggcactgatggaacggctgggccacccggagcgggcctgcccggtgattcatgtc
gccggcactaacggcaaagggtccaccgtggccatgattgcggccgctctgcgcgggcag
ggctggcgggtggggatgaccgtctcccccgacctgggggccatcaaccagcgggtccaa
atcggggagcggcccctggagccccggctctgggacctgctgggggccgaggtggaggaa
gccggcgccgggctcgcggacgtgcccagctttttcgaggccgtgaccgccctggctttc
ctggccttccgccggctggcggtagacgtggcggtggtggaggtggggctgggcggccgg
tgggatgccaccaatgtggtccctccgccgctcctgaccgtgatcactcccatcgccttc
gaccacatggaccgcctggggcataccatcaccgccatcgcgggggaaaaggcgggcatc
ctgaaaccgggcagccgcctggtgctggccgggcagccctatccggaagcggcagcggtg
gtgcgggcgcgggcggccgaggccggggtgccggtgcgggaggcggtggcctggccggga
ggcagcgatcaggaggggacctacctgcagttccccgacggcagcacggtgcgggtgccg
ctattgggggcctaccagctggataacctgcgcacggcctggacggcggtggaggagctg
gcggcggcaggatgggccgatccggggcgggcgcgggaggccctgtctacagtggaatgg
ccaggccgtttcgaggtggtgtcgcgggatcccctgatcgtgctggacggggcgcacaac
ctgcacggggccgccggcctggcccgctccctgcgccagccgccgtgggccggccggcgc
tggcagctggtgttcgccgccctcaacgacaagccggcgctggctatggccactgccttg
gcgccgctggccgccggggtggtggtgacccgcgtgccgggggagcgggggaccgacccg
gcggcggtggccgcggggctgcgcgagcgggggtttacggtgcccatcagcgtggaaccg
gatcccctgcaggcggtggcccgggcccgggaacggctgggccccggggaagggttgctg
gtgacgggatccctggctctcatggccggcctcaaggcgcaggggctccccggcccgcag
gactccgccgccttccggcgggcatccgggtga
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