Candidatus Hydrogenisulfobacillus filiaventi: R50_2473
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Entry
R50_2473 CDS
T08923
Symbol
pdhA
Name
(GenBank) Pyruvate dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
hfv
Candidatus Hydrogenisulfobacillus filiaventi
Pathway
hfv00010
Glycolysis / Gluconeogenesis
hfv00020
Citrate cycle (TCA cycle)
hfv00620
Pyruvate metabolism
hfv00785
Lipoic acid metabolism
hfv01100
Metabolic pathways
hfv01110
Biosynthesis of secondary metabolites
hfv01120
Microbial metabolism in diverse environments
hfv01200
Carbon metabolism
hfv01210
2-Oxocarboxylic acid metabolism
Module
hfv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hfv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
R50_2473 (pdhA)
00020 Citrate cycle (TCA cycle)
R50_2473 (pdhA)
00620 Pyruvate metabolism
R50_2473 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R50_2473 (pdhA)
Enzymes [BR:
hfv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
R50_2473 (pdhA)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Transketolase_N
Death_EDAR
Motif
Other DBs
NCBI-ProteinID:
CAB1129970
UniProt:
A0A6F8ZK46
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All DBs
Position
1:complement(2255454..2256506)
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AA seq
350 aa
AA seq
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MDRERWRAFLYDMLLARAFEERAAQAYSEGQIAGFLHLYPGEEAVAVGVIQAAEPSDYIV
STYREHVHALVRGIPARRVMAELFGRKDGVSGGMGGSMHLFDRERRFMGGYAIVGETFPI
AVGVAYAVAYRRLPEAVICFFGDGAVNQGTFHESLNMAGLWKLPVLFVCENNHYQIGTEI
HRHSAVVDLYRRAAAYNIPAEQVDGMDVVAVYEASRKALERVRAGEGPYFIEFETYRYRG
HSMADPGVYRPPAEVNAFAAHDPVAAAIRAAEFRYPPREELEAAGADSISRHTRRGFAHG
HLDEETVEAMRKQVETVVADAVAFAQASPEPTMEDAWAAFLANRRDETLL
NT seq
1053 nt
NT seq
+upstream
nt +downstream
nt
atggatcgggagcgctggcgggccttcctgtatgacatgctgttggcccgcgccttcgag
gaacgggcggcccaggcctattccgagggccagatcgcgggtttcctgcacctctacccc
ggcgaggaggcggtggcggtgggggtgatccaggccgctgagccctcggattatatcgtc
agcacctaccgggagcatgtacacgccctggtacgcggtatccccgcccgccgggtgatg
gccgagctgttcggccgcaaggacggggtcagcgggggcatgggggggtcgatgcacctc
ttcgaccgggagcggcgtttcatgggcggctacgccatcgtcggggagaccttccctatt
gcggtgggggtcgcctacgcggtggcctaccggcgtctgccggaagcggtcatctgcttc
ttcggcgacggcgccgtcaatcagggaaccttccacgagtccctcaacatggccgggctc
tggaaactgccggtcctcttcgtctgcgagaacaaccactaccagatcggcaccgagatt
caccgccattccgcggtggtggacctctaccggcgggcggcggcctacaacatccccgcc
gagcaggtggacggtatggatgtggtggcggtatacgaggccagccgcaaggccctggaa
cgggtgcgggcgggggagggtccttacttcattgagtttgaaacctaccgctaccggggg
cactccatggccgaccccggggtctaccggcccccggcggaagtcaacgccttcgcggcc
cacgacccggtggcggcggccatccgggccgcggagttccgctatccaccgcgcgaggag
ttggaggctgcgggggccgattccatcagccgccatacccggcgaggctttgcccacggc
cacctggacgaggagacggtggaggccatgcgcaagcaggtcgagacggtggtggccgat
gccgtcgccttcgcccaggccagtccggaacccacgatggaggatgcctgggcagcgttc
ctggccaaccgccgggacgagaccctcttgtag
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