Heterocephalus glaber (naked mole-rat): 101697318
Help
Entry
101697318 CDS
T02812
Symbol
Gart
Name
(RefSeq) phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00230
Purine metabolism
hgl00670
One carbon pool by folate
hgl01100
Metabolic pathways
hgl01523
Antifolate resistance
Module
hgl_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101697318 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101697318 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101697318 (Gart)
Enzymes [BR:
hgl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
101697318 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
101697318 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
101697318 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_4
ATP-grasp_2
ATP-grasp_3
Dala_Dala_lig_C
LUD_dom
RimK
Motif
Other DBs
NCBI-GeneID:
101697318
NCBI-ProteinID:
XP_004842377
UniProt:
G5BE86
LinkDB
All DBs
Position
Un
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSPRVKQVLVAPGNAGTACLEKISNTAISVGDHTALAQ
FCKDEKVAFVVVGPEAPLAAGIVGDLASAGVRCFGPTAEAAQLESSKRFAKEFMDRHRIP
TAQWRAFTKAEKACSFIMSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKTF
GAAGETVVVEELLEGEEVSCLCFTDGRTVVPMPPAQDHKRLLEGDLGPNTGGMGAYCPAP
QISKDLLLKIKNTILQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCSSLPSWLENHTAVTVVMASKGYPGAYTKGMEITGIPEA
QALGLEVFHAGTALKDGKVVTSGGRVLTVTAIRENLKSALEEAKKGLATIKFEGAVYRKD
IGFHAIAFLQQPRGLTYKDSGVDIAAGNMLVKKIQPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHSTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLRTTEAVVAGVAEACKQAGCALLGGETAEMPDMYPPGEYDLAGFAVGGMERYQKLP
HLEQIVEGDVVVGIASSGLHSNGFSLVRKIVAQSSLEYSSLAPGGCGDQTLGDLLLTPTR
IYSRSLLPVIRSGLVKAFAHITGGGLLENIPRVLPKKFGVDLDARTWRIPRVFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKDQTDHILREIQQRQEEAWVIGSVVACPEGSPRVKVKN
LIETMQINESVLVNGSLETHFPAQQKKARVAVLISGTGSNLQALIDSTQDPNSAAHIVVV
ISNKPAVAGLNKAEKAGIPTRVINHKLYKNREEFDGAIDQVLEEFATDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSEKVKVAEHKIFPKALQLVASGTIWLGENNKVCWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgcgtacttgtaattggcagtggaggaagggaacatacactggcctggaaa
ctggcacagtctcctcgtgtcaaacaagtattggttgccccaggaaatgcaggcactgcc
tgcttggaaaagatttcaaatactgccatctcagttggtgatcatacagcccttgctcag
ttctgcaaagatgagaaggttgcattcgtagttgttggaccagaggcacctctggctgcc
ggaattgttggggacttggcctctgcaggagtgcgatgctttggccccactgcagaagca
gctcagttagagtccagcaaaaggtttgccaaagagtttatggaccgacatagaatccca
actgcacagtggagagctttcaccaaagctgagaaggcctgcagcttcatcatgagtgct
gacttccctgctctggttgtgaaggccagcggccttgcggctgggaagggagtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtacaggagatcatgcaggagaaaactttt
ggagcagctggagaaacagttgttgttgaagaacttcttgaaggggaagaggtgtcttgt
ctgtgtttcaccgacgggaggacagtggtccccatgcccccagcccaggaccataagcga
ttactggaaggagatctgggacccaacacggggggaatgggagcctattgtccagcaccc
cagatttccaaggatttgttactaaaaattaaaaatactattcttcagaggacagtagat
ggcatgcagcaagagggcactccgtacacaggaattctgtatgctggtataatgctgacc
aaggatggcccaaaagtcttggagtttaattgccgttttggtgatccagagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttagatggcctg
ctgtgttcatctctgcccagttggctagaaaaccatactgcggtgactgtcgtcatggca
agcaaaggttatcctggagcctacaccaagggcatggagattacaggcattcccgaagct
caggctttaggactggaggtattccacgcaggcactgccctcaaagatgggaaagtagta
accagcgggggcagagtgctcacagtaacagccatccgggaaaatctcaaatcagctctt
gaggaagccaagaagggactcgccactatcaagtttgagggagctgtttataggaaggac
atcggctttcatgccatagctttcctccagcagcccaggggcctgacttacaaagactct
ggggtagacattgcagctggaaatatgctggttaagaaaattcagcctttagcaaaagct
acctccagacctggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctctgggacagatggtgttgggactaaactg
aagattgcccagctgtgcaataagcacagtaccattggtcaagatttggttgcaatgtgt
gtaaatgacattctggcgcaaggagcagagcccctctttttccttgattatttttcctgt
ggaaaacttgacctcaggacgacggaagctgttgttgctggagtcgctgaggcttgtaaa
caagctgggtgtgctctgctaggaggtgaaacggcagagatgccagacatgtatcctcct
ggagagtatgacctagcgggttttgctgtcggtggcatggagcggtaccagaaactccct
cacctggaacagatcgtggaaggggatgttgttgttggaatagcctcatctggtcttcat
agcaatggatttagccttgtgaggaaaattgtggcacagtcttcactggaatactcctct
ctagcacctggtggctgtggtgaccagactttaggagacttacttctaactccaaccaga
atctacagccgttcactgttacctgtcatacgttcaggacttgtcaaggcctttgcccat
attactggtggaggcttgctagaaaacattcccagagtcctccctaagaaatttggggtg
gatttagatgcccgcacctggaggatccccagagtcttttcatggttacagcaggaaggg
cagctctctgaagaagagatggccagaacatttaactgtggagttggagctgccctggtg
gtttcaaaagatcagacggatcacattctgagagagattcagcagcggcaggaggaggcc
tgggtgattggcagtgtggttgcatgccctgaaggttccccacgtgtgaaagtcaagaat
ctgattgaaaccatgcaaataaatgagtcggtgttggtgaatggctccctggaaactcat
ttccctgcccaacaaaaaaaggcaagagtggccgtcttgatatctggaacaggatcaaac
ctccaggcacttatagacagcactcaggatccaaacagtgctgctcacattgttgtcgtt
atctccaacaaacccgcagtggctggattaaacaaagctgaaaaagctggtattcccacc
agagtaattaatcacaaattatataaaaatcgtgaagaatttgacggtgccattgaccag
gtgcttgaagagtttgccacagacatagtctgtcttgcaggattcatgagaattctatct
ggcccctttgtcagaaaatgggatgggaaaatgctcaatatccacccatcactgctccct
tcttttaagggttcaaatgctcatgagcaagtcttggaagccggagtcacaatcactggg
tgcaccgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaagct
gttcctgtgaagagaggtgacactgttgcaactttgtctgaaaaagtaaaagtagcagag
cataaaatatttcctaaagctcttcagcttgtggccagtggaaccatatggcttggagaa
aacaacaaggtctgttgggtcaaagaagaataa
DBGET
integrated database retrieval system
