Heterocephalus glaber (naked mole-rat): 101697599
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Entry
101697599 CDS
T02812
Symbol
Htt
Name
(RefSeq) huntingtin
KO
K04533
huntingtin
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl05016
Huntington disease
hgl05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
101697599 (Htt)
05022 Pathways of neurodegeneration - multiple diseases
101697599 (Htt)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hgl03019
]
101697599 (Htt)
04131 Membrane trafficking [BR:
hgl04131
]
101697599 (Htt)
03029 Mitochondrial biogenesis [BR:
hgl03029
]
101697599 (Htt)
Messenger RNA biogenesis [BR:
hgl03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
101697599 (Htt)
Membrane trafficking [BR:
hgl04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
101697599 (Htt)
Mitochondrial biogenesis [BR:
hgl03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
101697599 (Htt)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_2
HEAT_EF3_N
Motif
Other DBs
NCBI-GeneID:
101697599
NCBI-ProteinID:
XP_004847425
UniProt:
A0AAX6PAK0
LinkDB
All DBs
Position
Un
AA seq
3112 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQAPPPQPPQPPPQAPPPPPPPPPGPSGPEEPLPRPKKELS
ATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCSDDVESDVRMVADECLNK
VIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKCRPYLVNLLPCL
TRTSRRPEESVQETLAAAIPKIMASFGNFANDNEIKILLKAFIANLKSSSPTVRRTAAGS
AVSICQHSRRTQYFYSWLLNVLLGLLVPVEEEHPTLLILGVLLTLRYLVPLLQQQVKDTS
LKGSFGVTRKEMEVSPSAEQLVQVYQLTLHHTKHQDHNVVTGALELLQQLFRTPPPELLQ
ALTTPGGLAQLSVAQEEARGRSGSIVELLVGGGSSCSPVFSRKQKGKVLLGEEAALEDDS
ESRSDASSSAFAASVKGEISGELAASSGVSTPGSMDHDIITEQPRSQHTLQADSVDLSSC
DLTSTATDGDEEDILSHSSSQISAVPSDPAMDLNDGTQASSPISDSSQTTTEGPDSAVTP
SDSSEIVLDSADSQFSGMQVCAPQDEAEAEAAAVLGSLPSGASGCLRSSSMEALQRAHLL
ESMGHNRQPSDSSVDKFVSRDEPAEPGDQENKPCWVKGDIGQSTDDDSAPLVHCVRLLSA
SFLLSGGKNVLVPDRDVRVSVKALALSCVGAAVALHPESFFSKLYKVPLDTVEYPEEQYV
SDVLNYIDHGDPQVRGATAILCGTLISSVLSRSRFHVGDWLGTIRTLTGNTFSLADCIPL
LRKTLKDESSVTCKLACTAVRHCVLSLCSSSYSGLGLQLLVDLLALRGSSYWLVRTELLE
TLAEMDFRLVSFLEAKAESLHRGAHHYTGLLKLQDRVLNNVVISLLGDEDPRVRHVAAAS
LVRLVPKLFYKCDQGQADPVVAVARDQSSVHLKLLMHETQPPSHFSVSTITRIYRGYSLL
PSITDVTMENNLSRVIAAVSHELITATTRALTFGCCEALCLLSAAFPVCVWSLGWHCGAP
PLSASDESRKSCTVGMATVILTLLSSAWFPMDISAHQDALILAGNLLAASAPKSLRSSWA
SEEEANPAATRQEEVWPALGDRTLVPMVEQLFSHLLKVINICAHVLDDVAPGPAIKAALP
SLTNPPSLSPIRRKGKEKEPGEQASAPLSPKKGSEASAVSRQSDTSGPVTASKSSSLGSF
YHLPSYLKLHDVLKATHANYKVTLDLQNNTEKFGGFLRSALDVLSQILELATLQDIGKCV
EEILGYLKSCFSREPMMATICVQQLLKTLFGTNLASQFDGLSSNPSKSQGRAQRLGSSSV
RPGLYHYCFMAPYTHFTQALADASLRNMVQAEQEHDTSGWFDVLQKVSTQLKTNFTSVTK
NREDKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQKQVLDLLAQLVQLRVNYCLLDSDQV
FIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHSKQIIGIPKIIQLCDGIMAS
GRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFIL
VLQQCHKENEDKWKRLSRQVADIILPMLAKQQMHIDSHEALGVLNTLFEILAPSSLRPVD
MLLRSMFVTPSTMASVSTVQLWISGILAILRVLISQSTEDIVLSRIQELCFSPYLISCSV
INRLRDGDSNSASEEHSEGKQSKNSPEETLSRFLLQLVGILLENIVTKQLKVEMTEQQHT
FYCQELGTLLMCLIHIFKSGMFRRVTAAATRLFTNDGCEGSFYTLESLNERVRSMAPTHP
ALVLLWCQILLLANHTDHHWWAEVQQTPRRHSLSCTKSLSPQVSSEEEEEDSDSAAQLGM
CNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQDLISLCHEPPVQDFISAVHRNSA
ASGLFIQAIQSRCENLSTPTTLKKTLQCLEGIHLSQSGTVLTLYVDRLLGTPFRALARRV
DTLACRRVEMLLAANLQSSTAQLPAEELNRIQEHLQSSGLAQRHQRLYSLLDRFRLSTAQ
DSLSPLPLVTSHPLDGDGHMSLETVSPDKDWYIRLVRSQCWTRSDAALLEGAELVKHLPA
EDMRVFMMSSEFNLSLLAPCLSLSLSEVAAGQRSPLFEAARGVTLDRVTSIVEQLPAVHQ
VFQPFLPTQPTAYWSKLNGLFGDATLYQSLTTLARALAQYLVVVSKVPAHLHLPPEKEKD
TVKFVAMTLEALSWHLIHEQIPLSLDLQAGLDCCCLALQQPGLWSVVSSAEFVTHACSLI
HCVRFILEAVAVQPGDQLLSPESRTRTLRAVQEEEVNVDTQNPKFITTACEMMAEMVESL
QSVLALGHKRNSSVPTFLTAVLKNIVVSLARLPLVNSYTRVPPLVWRLGWSPKPGGDFGT
VFPEIPVEFLQEKEVFKEFIYRINTLGWTSRTQFEETWATLLGVLVTQPLVMEQEESPPE
EDTERTQIHVLAVQAITSLVLSAMTVPVAGNPAVSCLEQQPRNKPLKALDTRFGRKLSMI
RGIVEQEIQAMVSKRENIATHHAYQAWDPVPSLSPATTGALISHDRLLLQINPERELGNM
SYKLGQVSIHSVWLGNNITPLREEEWDEEEEEEADVPAPASPPVSPVNSRKHRAGVDIHS
CSQFLLELYSRWILPSSSARRTPVILISEVVRSLLVISDLFTERNQFEMMYSTLTELRRV
HPSEDEILIQYLVPATCKAAAVLGMDKAVAEPVSRLLESTLRSSHLPSQIGALHGILYVL
ECDLLDDTAKQLIPYISDYLLSGLKGAAHCVNVHSQQHVLVMCATAFYLIENYPLDVGPE
FSASVIQMCGVMLSGSEESTPSIIYHCALRGLERLLLSEQLSRLDTESLVKLSVDRVNVH
SPHRAMAALGLMLTCMYTGKEKTSPGRTSDPNPAAPDSESVIVAMERVSVLFDRIRKGFP
CEARVVARILPQFLDDFFPPQDVMNKVIGEFLSNQQPYPQFMATVVYKVFQTLHSAGQSS
MVRDWVMLSLSNFTQRTPVAMAMWSLSCFFVSASTSPWVSAILPHVISRMGKLEQVDVSL
FCLVATDFYRHQIEEELDRRAFQSVFEVVAAPGSPYHRLLTCLRNVHKVMTC
NT seq
9339 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccttagaaaagctgatgaaggcctttgagtccctcaagtccttccagcagcag
caggcgccgccgccgcagccccctcagccgccgcctcaggcgccgccgcccccgcctccg
ccgccgcctggcccgtcagggcccgaggagccgctgccccgaccaaagaaggaactctca
gccaccaagaaagaccgtgtgaatcattgtctgacaatatgtgaaaacatagtggcgcag
tctctcagaaattctccagaatttcagaaactcctgggcatcgccatggaacttttcctg
ttgtgcagtgatgatgtggagtcagatgtcaggatggtggctgacgaatgcctcaacaaa
gttatcaaagctttgatggattccaacctgccaaggctccagttagaactttacaaggaa
atcaagaagaacggcgcccctcggagcttgcgtgctgccctgtggaggtttgctgagctg
gctcacctggttcggcctcagaagtgcaggccttacctggtgaatcttctgccatgcttg
actcgaacaagcaggagacctgaggaatccgtccaggagaccttggctgcagctattccc
aaaattatggcttcttttggcaattttgcaaatgacaatgaaattaagattctgttgaag
gcgttcatagcaaatctgaagtcaagctcccctacggtccggcgcacagcagctggctcg
gcagtgagcatctgccagcactccaggaggacgcagtacttctatagctggctgctcaac
gtgctcctgggtctactggttccagtggaggaagaacaccctacactcctgatcctcggg
gtgctgcttacgttgaggtatctggtgcccttgctgcagcagcaggtcaaggacacaagc
ctgaaaggcagctttggggtgactcgaaaagagatggaagtgtccccgtctgcagagcag
ctggtccaggtttaccagctgactttgcatcacacaaagcaccaagaccacaatgtggtg
acaggcgccctggagctcttgcagcaactcttccgcacacccccgcctgagctgctgcag
gcgctgaccactcctgggggcctggctcagctctctgtggctcaggaggaggcccggggc
cgcagtgggagcatcgtggagcttctagttggagggggttcttcatgcagtcctgtcttt
tcaagaaagcaaaaagggaaagtgctcctaggagaagaagcagccttggaggatgactcc
gaatcaaggtcagatgccagcagctcggcctttgcagcctctgtaaagggtgaaatcagt
ggagagctggcagcctcctcgggggtctctacacctgggtccatggatcacgatatcatc
actgagcagcccaggtcacagcacacactgcaggctgactctgtggatctgtccagctgt
gacttaaccagcactgccaccgatggagatgaagaggacatcttgagccacagttccagc
caaatcagtgctgttccttccgaccctgccatggacctgaatgatgggacccaggcctct
tcacccatcagtgacagctcccagaccaccacagaagggcctgattcagctgtgacccct
tctgacagctctgagattgtgttagacagtgccgacagccagttctcaggcatgcaggtc
tgcgccccacaggacgaggctgaggccgaggccgcggctgtgctgggcagccttccttcc
ggggcctcggggtgtctcagaagctcttccatggaagcccttcagcgagcacatttattg
gagagcatgggtcacaacaggcagccttctgacagcagtgtagataagtttgtatcaaga
gatgaacctgctgaaccaggcgatcaggagaacaagccttgctgggtcaaaggcgacata
ggacagtccactgatgacgattctgctcctctggtccattgtgtccgccttttatctgct
tcatttttgctcagtggaggaaaaaatgtgctggttccggacagagatgtgagggtcagt
gtgaaggccctggcccttagctgtgttggggcagctgttgccctgcatccggaatctttc
ttcagcaaactgtataaagtacctctggacactgtggaataccctgaggagcagtatgtc
tctgacgtcttgaactacatcgaccacggagacccacaggtccgaggagccactgccatt
ctctgcggaaccctcatctcctctgtgctcagtaggtcccgcttccacgtgggggactgg
ctgggcaccattaggacactgacaggaaatacattttctctagcggactgcatccctctg
ctgcggaaaacattgaaggatgaatcttctgtgacttgcaagttggcttgtacagctgtg
aggcactgtgtcctgagtctttgcagcagcagttatagcggcctaggactgcagctgctg
gtggacctgctggccctgaggggaagctcctactggctggtgaggactgagctcctggag
acgcttgcagagatggacttccggctggtgagctttttggaggcaaaagcagagagctta
cacagaggggctcatcattatacaggacttttaaaactgcaagaccgagtgctcaataat
gttgtcatctctttgcttggggacgaagaccccagggtgcgacacgttgctgcggcatca
ttagtgaggctcgtcccaaagctgttctataaatgtgaccaaggacaggctgatccagtg
gtggctgtggcaagagaccaaagcagtgttcacctgaaactcctcatgcacgagacacag
cctccctcacacttctccgtcagcaccatcacgagaatctatagaggctatagtttacta
ccaagcataacagatgtcaccatggagaataacctctcgagagttattgctgctgtttct
catgagctgatcacggccaccacgcgtgcgctcacttttggatgctgcgaagctttgtgt
cttctgtcagccgcctttccagtttgtgtgtggagcttaggttggcattgtggagcaccc
ccactgagtgcctccgatgagtccaggaagagctgcactgttgggatggccaccgtgatt
cttaccctgctctcctcggcttggttcccgatggacatctctgcccatcaagacgccttg
atcttggcaggaaacttgctcgcagctagtgcccccaagtctctgaggagttcatgggcc
tctgaagaagaagccaaccccgctgccaccagacaggaggaggtgtggcctgccctgggg
gaccggaccctggtgcccatggtggagcagctcttctcccacctgctgaaggtgatcaac
atctgtgcccacgtcctggatgacgtggctcctgggccagcaatcaaggcagccttgcct
tctctgacaaaccccccttccctgagtcccatccgccgcaaaggcaaggagaaggaacca
ggagaacaagcctctgcgccattgagtcccaagaagggcagtgaggcgagtgcagtctcc
cgacaatccgatacctcgggcccagttacagccagtaaatcctcgtcactggggagcttc
tatcatcttccttcatacctcaagctgcatgacgtcctaaaggccactcacgccaactac
aaggtcaccttggatcttcagaacaacactgaaaagtttggggggttcctgcgctctgcc
ttggatgttctctcccagattctagagctggcgacgctgcaggacattgggaagtgtgtc
gaagagatcctggggtacctgaaatcctgctttagtcgggaaccaatgatggctactatt
tgtgtccagcagctgttgaagactctctttgggacaaacctggcttcccagttcgatggc
ttgtcttccaaccccagcaagtctcaaggccgagcgcagcgcctcggctcttccagtgtg
aggccgggcctgtaccactactgcttcatggccccgtacacccacttcacacaggccctt
gcggatgccagcctgaggaacatggtgcaggcagagcaggagcacgacacctcgggatgg
tttgatgtgctccagaaagtgtccactcagctcaagacaaacttcacgagtgtcacaaag
aaccgggaagacaagaatgctattcacaaccacattcgtttatttgagcctcttgtcata
aaagctttgaaacagtatacaacgacgacctcggtgcagttgcagaagcaggttttggat
ttgctggcacagctggttcagttacgggtgaattactgccttctggactcggatcaggtg
ttcattggatttgttctgaagcagtttgaatacattgaagtgggccagttcagggaatcg
gaggcgattattccaaacatctttttcttcctagtattgctctcttatgaacgataccat
tccaagcagattattggaattcctaaaatcatccagctttgcgatggcatcatggccagc
gggaggaaggccgtgacacatgcaatcccagctctgcagcccatagtccatgaccttttt
gtgttaagaggaacaaataaagctgatgcagggaaagaacttgaaactcagaaggaggtg
gtggtgtcgatgctgctgagactcatccagtaccatcaggtgctggagatgttcatcctc
gtcctgcagcagtgccacaaggagaacgaggacaagtggaaacggctgtctcggcaggtc
gctgacatcatcctgcccatgcttgccaagcagcagatgcatatcgactcgcacgaagcc
cttggagtgttaaacactttgtttgagattctggccccttcctccctccgcccggtggac
atgcttttgcgcagtatgttcgtcactccaagcacgatggcctcagtgagcactgttcag
ctgtggatatctggaattctagccatcctgagggttctcatttcccagtcaactgaagat
attgttctctctcgcattcaggagctctgcttctctccatatttaatttcctgttcagtg
attaacaggttgagagatggggacagtaattcagcatcagaagaacacagtgaagggaaa
caatcgaagaattcgccagaagaaacattgtcaaggtttctgttacaactggttgggatc
ctgttagagaacattgttacaaagcagctgaaagtggaaatgactgaacagcagcacact
ttctactgccaagagctgggcactctgctcatgtgcctcatccacatcttcaagtcgggg
atgttccggagagtcaccgcggctgccaccagactcttcaccaacgatggctgtgagggc
agcttctacacgctggagagcctgaatgagcgcgtgcgctccatggcgcccacacaccca
gccctggtgctgctgtggtgccagatcctgctgctcgccaaccacaccgaccaccactgg
tgggcagaggtgcagcagacacccaggagacacagtctgtcgtgcacgaagtcactcagc
ccccaggtgtccagcgaggaggaggaggaggactctgactcagccgctcaactgggaatg
tgcaatagagagatcgtgcgaagaggggccctcattctcttctgtgattatgtttgtcag
aacctccatgactccgagcacctaacatggctcattgtgaaccacattcaagatctgatc
agtctttgccatgagcctccagtgcaggacttcatcagtgccgtccatcggaattctgcc
gccagtggccttttcatccaagcaattcagtctcgttgtgaaaatctttccactccaacc
actctgaagaagacgctgcagtgcttggaaggcatccacctcagccagtcgggcaccgtg
ctcacactgtatgtggacaggctcctgggcacccctttccgagcactggctcgaagggta
gacaccctggcctgtcgccgggtagaaatgctgctggctgcaaacttacagagcagcaca
gcccagttgccagcagaagaactgaacagaatccaggaacatcttcagagcagtgggctt
gcgcagagacaccaaaggctgtattccctgctggacaggttccgtctttccactgcacaa
gactcactcagccccttgcccctggtcacctcccacccgctggatggggatgggcacatg
tccctggagacagtgagcccagacaaagactggtacatccgccttgtcaggtcccagtgt
tggaccaggtcagatgctgcactgctggaaggtgcggagctggtgaagcacctccccgcc
gaggacatgcgtgtcttcatgatgagctcggagttcaacctaagcctattggccccgtgc
ttaagcctcagcctgagtgaagttgcagctggccagaggagccccctttttgaagcagcc
cgtggggtgactctggaccgtgtgaccagcatcgttgagcagcttcctgctgtccatcaa
gtcttccagcccttcctgcccacacagcccacagcctactggagcaagttgaatggtcta
tttggggatgccacattgtaccagtccctcaccacactggcccgggccctggcacagtac
ctggtggtggtgtccaaagtgcctgcccatttgcaccttcctcctgagaaggaaaaagac
accgtgaagtttgtggcgatgaccctggaggccctgtcatggcatttgatccacgagcag
atcccactgagtctggacctccaggctgggctggactgctgctgcctggccctgcaacag
cctggtctctggagtgtggtctcctccgccgagtttgtgacccacgcctgctccctcatc
cactgtgtgcgattcatcctggaagctgttgcagtgcagcctggagaccagcttctcagt
ccagaaagtcggacgcgcaccctaagggccgtccaagaggaggaagtaaatgtagacaca
cagaatcccaaattcatcaccacggcctgtgagatgatggcagagatggtggaatccctg
cagtcggtgctggccttgggccacaagaggaacagcagtgtgcctacatttctcacagcg
gtgctcaagaacattgtggtcagcctggcccgcctccccctcgtcaacagctacactcga
gtgccgcccttggtgtggagactcgggtggtcccccaagccaggaggggactttggcact
gtgttccccgagattcccgtggagttcctgcaggagaaggaagtcttcaaggagttcatc
taccgcatcaacactctagggtggaccagtcgtacccagtttgaggaaacttgggccacc
ctactcggtgtcctggtgacccagcctcttgtgatggagcaggaggagagcccgcctgag
gaagacacagagaggacccagatccatgtgctagctgtgcaggccatcacctccctggtg
ctcagtgccatgaccgtgcctgttgctggcaacccagcagtgagctgtctggagcagcag
ccccggaacaagcccctcaaagctcttgataccaggtttgggaggaaattgagcatgatc
agagggattgtagagcaggagattcaagcgatggtttccaagagggagaatattgccacc
catcacgcataccaggcatgggatcctgttccctctctgtcacccgccactacaggtgcg
ctcatcagtcatgacaggctgctgctgcagatcaaccctgagcgggagctgggcaacatg
agctacaagctgggccaggtgtccattcactccgtgtggctggggaacaacatcacccct
ctgagagaggaggagtgggatgaggaggaggaagaggaggctgatgtccctgcacctgca
tccccacccgtgtctccagtcaactccaggaaacaccgggctggagtcgacatccactcc
tgttcacagtttctgctcgagttgtacagccggtggatcctgccctccagctcggccaga
aggaccccggtcatcctgatcagcgaagtggttcgctctcttctcgtcatctcagatttg
ttcactgagaggaaccagtttgagatgatgtattcgacgttgacggaactgcggcgggta
cacccttcggaagatgagattctcatccagtacctagtgccggccacctgtaaagcggct
gctgtcctcggaatggacaaggccgtggcagagccagtcagccgcctgctggagagcacc
ctcaggagcagccacctgcccagccagatcggagccctgcatggcatcctgtatgtgctg
gagtgcgacctcctggatgacaccgcaaagcagctcatcccgtacatcagcgactacctc
ctgtccgggctcaagggggcagcccactgcgtgaacgtgcacagccagcagcacgtgctg
gtgatgtgtgccactgctttttatctcatcgagaactacccgctggacgtggggcctgag
ttttcagcgtcagtcatacagatgtgtggagtgatgctgtccggcagtgaggagtccact
ccctccatcatctaccactgcgccctccgaggcctggagcgcctcctactctccgagcag
ctctcccggctggacacagagtccctagtcaagctgagtgtggacagagtgaacgtgcac
agcccacaccgggctatggccgccctgggtctgatgctcacctgcatgtacaccggaaag
gagaaaaccagtccaggcagaacttcagaccctaaccctgcagccccagacagcgagtcc
gtgattgtggccatggagcgggtgtctgttctcttcgataggatcaggaagggcttcccc
tgtgaggcccgggtggtggcaaggatcctgccacagttcctggacgacttcttcccaccc
caggatgtcatgaacaaggtcattggagagttcctgtccaaccagcagccgtacccacag
ttcatggctactgtcgtgtacaaggtgttccagactctgcacagtgccggacagtcgtcc
atggtccgggactgggtcatgctgtccctgtccaacttcacgcagaggaccccagttgcc
atggccatgtggagcctctcctgcttcttcgtcagcgcgtccaccagcccctgggtgtca
gccatcctccctcacgtcatcagccggatgggcaagctggagcaggtggacgttagcctt
ttctgcctagtcgccacagacttctacagacaccagatagaggaggagctcgaccgcagg
gccttccagtctgtgtttgaggtggtcgcggcaccgggaagcccgtaccaccggctgctg
acttgtttgagaaacgtccacaaggtcatgacttgctga
DBGET
integrated database retrieval system
