Heterocephalus glaber (naked mole-rat): 101697984
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Entry
101697984 CDS
T02812
Symbol
Smurf2
Name
(RefSeq) SMAD specific E3 ubiquitin protein ligase 2
KO
K04678
E3 ubiquitin ligase SMURF1/2 [EC:
2.3.2.26
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04120
Ubiquitin mediated proteolysis
hgl04137
Mitophagy - animal
hgl04144
Endocytosis
hgl04340
Hedgehog signaling pathway
hgl04350
TGF-beta signaling pathway
hgl04520
Adherens junction
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101697984 (Smurf2)
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
101697984 (Smurf2)
04350 TGF-beta signaling pathway
101697984 (Smurf2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101697984 (Smurf2)
04137 Mitophagy - animal
101697984 (Smurf2)
09144 Cellular community - eukaryotes
04520 Adherens junction
101697984 (Smurf2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hgl04131
]
101697984 (Smurf2)
04121 Ubiquitin system [BR:
hgl04121
]
101697984 (Smurf2)
03029 Mitochondrial biogenesis [BR:
hgl03029
]
101697984 (Smurf2)
Enzymes [BR:
hgl01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
101697984 (Smurf2)
Membrane trafficking [BR:
hgl04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
101697984 (Smurf2)
Autophagy
Mitophagy
Other mitophagy associated proteins
101697984 (Smurf2)
Ubiquitin system [BR:
hgl04121
]
Ubiquitin ligases (E3)
HECT type E3
101697984 (Smurf2)
Mitochondrial biogenesis [BR:
hgl03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-independent mechanism factors
101697984 (Smurf2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
GpA_nuclease
Motif
Other DBs
NCBI-GeneID:
101697984
NCBI-ProteinID:
XP_012923086
UniProt:
A0A0P6K6J8
LinkDB
All DBs
Position
Un
AA seq
748 aa
AA seq
DB search
MSNPGGRRNGPVKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPK
WNQHYDLYIGKSDSVTISVWNHKKIHKKQGAGFLGCVRLLSNAINRLKDTGYQRLDLCKL
GPNDNDTVRGQIVVSLQSRDRIGTGGQVVDCSRLFDNDLPDGWEERRTASGRIQYLNHIT
RTTQWERPTRPASEYSSPGRPLSCFVDENTPISGTNGATCGQSSDPRLAERRVRSQRHRN
YMSRTHLHTPPDLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLSNINCEELGPLP
PGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLNRQNQLKDQQQQQVVSLCPDDT
ECLTVPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWK
RLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHL
SYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILEND
ITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLA
LQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVNDWKVNTRLKHCTPDSNIVKWFWKAV
EFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRI
DIPPYESYEKLYEKLLTAIEETCGFAVE
NT seq
2247 nt
NT seq
+upstream
nt +downstream
nt
atgtctaaccccggaggccggcggaacgggcccgtcaagctgcgcctgacagtactctgt
gcaaaaaacttggtgaagaaggattttttccgacttcctgatccatttgctaaggtagtg
gttgatggatctggacaatgccattctacagatactgtgaagaatacactcgatccaaaa
tggaatcaacattatgacctgtatattggaaagtctgattcagttacaatcagtgtatgg
aatcacaagaagatccataaaaaacaaggtgctggatttcttggttgtgttcgtcttctt
tccaatgccatcaaccgcctcaaagacactggttatcagaggttggatctatgcaaactt
gggccaaatgacaatgatacagttagaggacagatagtagtaagtcttcagtccagagac
cgaataggcacaggaggacaagttgtggactgcagtcgtttgtttgataatgatttacca
gacggctgggaagaaaggagaactgcctctggacgaatccaatatctaaaccacataaca
agaactacacaatgggaacgcccaacaagaccggcatctgaatattctagtcctggcaga
cctcttagctgctttgttgatgagaacactccaattagtggaacaaatggtgcaacatgt
ggacagtcttcagatcccaggctggcagagaggagagtcaggtcacagcgacatagaaat
tacatgagcaggacacatttacatactcctccagacctaccagaaggctatgaacagagg
acaacgcagcaaggtcaggtgtatttcttacacactcagactggtgtgagcacatggcat
gatccgagagtacctagggatcttagcaacatcaattgtgaagagcttggtcctttgcct
cctggatgggagatccgcaatacagcaacaggcagagtttatttcgttgaccataacaac
agaacaacacaatttacagatcctcggctctctgctaacttgcatttagttttaaatcgg
cagaaccagttgaaagaccaacagcaacagcaagtggtgtcattatgcccggatgataca
gagtgcctgacagtaccaagatacaagcgagacctggttcagaaactaaaaatcttgcgc
caagaactttcccagcaacagcctcaggctggccactgccgcattgaggtttccagggaa
gagatttttgaggagtcatatcgacaggtcatgaaaatgagaccaaaagatctctggaag
cgattaatgataaaatttcgtggagaagaaggccttgattatggaggggttgctagggag
tggttgtatctcttgtcacatgagatgttgaatccatactatggcctgttccagtactca
agagatgatatctacacattacagatcaatcctgattctgctgttaatccagaacatttg
tcgtatttccactttgttggacgaataatgggaatggctgtgtttcatggacattacatt
gatggtggttttacactgcctttttataaacagttgcttggaaagtcaattactttggat
gacatggagttagttgatccagaccttcataatagtttggtgtggatacttgagaatgat
attacaggtgttttggaccataccttctgtgttgaacataatgcatatggtgaaattatc
cagcatgaacttaaaccaaatggcaaaagtatccctgttactgaagaaaataaaaaagag
tatgtcagattgtatgtgaactggagatttttacgaggcattgaggctcaattcctggct
ctgcagaaaggatttaatgaagtaattccacagcatctgctgaagacatttgatgagaag
gagttagagctcattatttgtggacttggaaagatagatgtcaatgattggaaagtaaac
acccggttaaagcactgtacaccagacagcaatattgtcaagtggttctggaaagctgtg
gagttttttgatgaagagcggcgagcgcgattgctacagtttgtaacaggatcatctaga
gtgcctctgcagggcttcaaagcactacaaggtgctgcaggcccacggctcttcaccata
caccagatcgacgcctgcactaacaatctgcccaaagcccacacgtgcttcaatcgaata
gacattccgccctatgaaagctatgaaaagctctatgaaaagctgctaacagccattgaa
gaaacatgtggatttgctgtggaatga
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