KEGG   Heterocephalus glaber (naked mole-rat): 101698044
Entry
101698044         CDS       T02812                                 
Symbol
Ppp1cb
Name
(RefSeq) protein phosphatase 1 catalytic subunit beta
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl03015  mRNA surveillance pathway
hgl04022  cGMP-PKG signaling pathway
hgl04024  cAMP signaling pathway
hgl04114  Oocyte meiosis
hgl04218  Cellular senescence
hgl04261  Adrenergic signaling in cardiomyocytes
hgl04270  Vascular smooth muscle contraction
hgl04390  Hippo signaling pathway
hgl04510  Focal adhesion
hgl04611  Platelet activation
hgl04720  Long-term potentiation
hgl04728  Dopaminergic synapse
hgl04750  Inflammatory mediator regulation of TRP channels
hgl04810  Regulation of actin cytoskeleton
hgl04910  Insulin signaling pathway
hgl04921  Oxytocin signaling pathway
hgl04931  Insulin resistance
hgl05031  Amphetamine addiction
hgl05034  Alcoholism
hgl05168  Herpes simplex virus 1 infection
hgl05205  Proteoglycans in cancer
hgl05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    101698044 (Ppp1cb)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    101698044 (Ppp1cb)
   04024 cAMP signaling pathway
    101698044 (Ppp1cb)
   04022 cGMP-PKG signaling pathway
    101698044 (Ppp1cb)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101698044 (Ppp1cb)
   04218 Cellular senescence
    101698044 (Ppp1cb)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101698044 (Ppp1cb)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101698044 (Ppp1cb)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101698044 (Ppp1cb)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101698044 (Ppp1cb)
   04921 Oxytocin signaling pathway
    101698044 (Ppp1cb)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101698044 (Ppp1cb)
   04270 Vascular smooth muscle contraction
    101698044 (Ppp1cb)
  09156 Nervous system
   04728 Dopaminergic synapse
    101698044 (Ppp1cb)
   04720 Long-term potentiation
    101698044 (Ppp1cb)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101698044 (Ppp1cb)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101698044 (Ppp1cb)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    101698044 (Ppp1cb)
  09165 Substance dependence
   05031 Amphetamine addiction
    101698044 (Ppp1cb)
   05034 Alcoholism
    101698044 (Ppp1cb)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    101698044 (Ppp1cb)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    101698044 (Ppp1cb)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hgl01009]
    101698044 (Ppp1cb)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hgl03021]
    101698044 (Ppp1cb)
   03019 Messenger RNA biogenesis [BR:hgl03019]
    101698044 (Ppp1cb)
   03041 Spliceosome [BR:hgl03041]
    101698044 (Ppp1cb)
Enzymes [BR:hgl01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     101698044 (Ppp1cb)
Protein phosphatases and associated proteins [BR:hgl01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     101698044 (Ppp1cb)
Transcription machinery [BR:hgl03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     101698044 (Ppp1cb)
Messenger RNA biogenesis [BR:hgl03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     101698044 (Ppp1cb)
Spliceosome [BR:hgl03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    101698044 (Ppp1cb)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 101698044
NCBI-ProteinID: XP_004839290
UniProt: A0AAX6NY18
LinkDB
Position
Un
AA seq 327 aa
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI
CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ
SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL
DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
KAKYQYGGLNSGRPVTPPRTANPPKKR
NT seq 984 nt   +upstreamnt  +downstreamnt
atggcggacggggagctgaacgtggacagcctcatcacccgcctgctggaggtacgagga
tgtcgtccaggaaaaattgtgcagatgactgaagcagaagttcggggtttatgtatcaag
tctcgtgagatctttctcagccagcctattcttttggaattggaggcaccactgaaaatt
tgtggagatattcatggacaatacacagatttgctgagattatttgaatatggaggtttc
ccaccagaagccaactatcttttcttaggagattatgtggacagaggaaagcagtctttg
gaaaccatttgtttgctattggcttataaaatcaaatacccagaaaacttctttctctta
agaggaaaccatgaatgtgctagcatcaatcgcatttatggattctatgatgaatgcaaa
cgaagatttaatattaaattgtggaagaccttcactgattgttttaactgtctgcctata
gctgccattgtggatgagaagatcttctgttgtcatggaggactgtcaccagacctgcaa
tctatggagcagattcggagaattatgagacccactgacgtccctgacacaggtttgctt
tgtgatttgctgtggtctgacccagataaggatgtgcagggttggggagaaaatgatcgt
ggtgtttccttcacttttggagctgatgtagtcagtaaatttctgaatcgtcatgattta
gacttgatttgtcgagctcatcaggtagtagaagatggatatgaattttttgctaaacga
cagttggtaaccctattttcagccccaaattactgtggtgaatttgacaatgctggtgga
atgatgagtgtggatgaaactttgatgtgttcatttcagatactaaaaccatctgaaaag
aaagctaagtaccagtatggtggactgaattctggacgtcctgtcactccgcctcgaaca
gctaatccaccgaagaaaaggtga

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