Heterocephalus glaber (naked mole-rat): 101699617 Help Entry 101699617         CDS       T02812                                  Symbol Nos2 Name (RefSeq) nitric oxide synthase 2   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00220   Arginine biosynthesis hgl00330   Arginine and proline metabolism hgl01100   Metabolic pathways hgl04020   Calcium signaling pathway hgl04066   HIF-1 signaling pathway hgl04146   Peroxisome hgl04371   Apelin signaling pathway hgl04926   Relaxin signaling pathway hgl05010   Alzheimer disease hgl05014   Amyotrophic lateral sclerosis hgl05022   Pathways of neurodegeneration - multiple diseases hgl05133   Pertussis hgl05140   Leishmaniasis hgl05142   Chagas disease hgl05145   Toxoplasmosis hgl05146   Amoebiasis hgl05152   Tuberculosis hgl05200   Pathways in cancer hgl05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     101699617 (Nos2)    00330 Arginine and proline metabolism     101699617 (Nos2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     101699617 (Nos2)    04066 HIF-1 signaling pathway     101699617 (Nos2)    04020 Calcium signaling pathway     101699617 (Nos2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     101699617 (Nos2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     101699617 (Nos2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101699617 (Nos2)   09162 Cancer: specific types    05222 Small cell lung cancer     101699617 (Nos2)   09171 Infectious disease: bacterial    05133 Pertussis     101699617 (Nos2)    05152 Tuberculosis     101699617 (Nos2)   09174 Infectious disease: parasitic    05146 Amoebiasis     101699617 (Nos2)    05145 Toxoplasmosis     101699617 (Nos2)    05140 Leishmaniasis     101699617 (Nos2)    05142 Chagas disease     101699617 (Nos2)   09164 Neurodegenerative disease    05010 Alzheimer disease     101699617 (Nos2)    05014 Amyotrophic lateral sclerosis     101699617 (Nos2)    05022 Pathways of neurodegeneration - multiple diseases     101699617 (Nos2) Enzymes [BR:hgl01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      101699617 (Nos2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 NAD_binding_6 Motif Other DBs NCBI-GeneID:  101699617 NCBI-ProteinID:  XP_004857022 UniProt:  A0AAX6PQT9 LinkDB All DBs Position Un AA seq 1148 aa AA seqDB search MREGLSAACEAARPRLYRFLRRILPPKPTRCLRASPETQDDPKYCSPSKRQNGSSQPLLG MAKKTPESQSKPHEPSQTCPQHMRIKNWGSGMILQDTLHNKAKTNFTCKSKSCLGSIMNP RSLTRGPRDKPTPLDELLPQAIEFVNQYYDSFKEAKIEEHLARVEAVTKEIETTGTYQLT GDELIFATKLAWRNAPRCIGRIQWSNLQVFDARSCTTAQEMFEHICRHLRYATNNGNIRS AITVFPQRTDGKRDFRIWNAQLIRYAGYQMPDGTIRGDPANLEFTQLCIDLGWKPHYGRF DVLPLVLQADGRDPELFEIPRDLVLEVPMEHPKYEWFQELGLKWYALPAVANMLLEVGGL EFPGCPFNGWYMGTEIGVRDFCDAQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVAV LHSFQKQNVTIMDHHSAAESFMKHMQNEYRTRGGCPADWIWLVPPMSGSITPVFHQEMLN YILSPFYYYQVDAWKTHVWQDEKRRPRRREIPFRVLARAVLFASVLMHKTMASRVRATIL FATETGKSEALAQDLGALFSCAFNPKVLCMDEYRLSTLEEEQLLLVVTSTFGNGDCPGNG ETLKKSLFILKKLTNTFRYAVFGLGSSMYPRFCAFAHDIDLKLSQLGASQLTPVGEGDEL SGQEDAFRTWAVQTFKAACEAFDVRGKHHIQIPKLYTSTVTWEPHHYRLVQDLQPLDLNK ALSRLHAKDVFTMRLKSQQNLQSPKSSRTTLLVELSCEDSRGLAYLPGEHLGVFPCNQPA LVQGVLERVVDSLGAHNIMRLEALDDSGSYWVKAKRLPPCSLSQALTYFLDITTPPTQLQ LQKLARLATEQAERQRLETLSQPSEYNKWKFTNSPTFLEVLEEFPSLRVPAAFLLSQLPI LKPRYYSISSSPDHTPSEVHLTVAVVAYRTQDARGPLHRGVCSTWLSNLKPQDPVPCFVR RVSSFQLPKDPSHPCILIGPGTGIAPFRSFWQQRLHNSEHKGLQGGRMTLVFGCRHPDED HIYKEEMLQMARKGVLHEVHTAYSRLPGKPKVYVQDILRQQLAGEVLRVLHEEPGHLYVC GNVLMAQDVAYTLKQLVAAKLNLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKKDRAE RPPGDIKL NT seq 3447 nt NT seq  +upstreamnt  +downstreamnt atgcgtgaggggctgagcgcggcgtgtgaggccgcgcggccgcggctctacaggttcctg cgcaggatcctcccaccaaagcccacgcgatgcctccgagctagcccagaaacacaggat gaccccaaatattgcagccctagcaagcgccaaaatggatcctcccagccccttctgggg atggctaagaagactccagaatcccagagcaagccacatgagccttcacagacctgcccc cagcacatgaggatcaaaaactggggcagtgggatgattttgcaagacacactccacaac aaggccaaaacgaattttacttgcaagtccaaatcttgcctggggtccatcatgaaccca agaagtttgaccagaggacccagggacaagcctacccctctggatgaacttctacctcaa gctatagaatttgtcaaccagtattatgactccttcaaagaggcaaaaatagaggaacat ctggccagggtggaagcagtaacaaaggagatagaaacaacaggaacctaccagctgaca ggagatgagctcatcttcgccaccaagcttgcctggcgtaacgccccccgctgcattggg aggatccagtggtccaacctgcaggtcttcgatgcccgcagctgtaccacagcccaggag atgtttgaacacatctgcagacacctgcgctatgctaccaacaatggcaacatcaggtcg gccatcaccgtgttcccccagcggactgatgggaagcgtgacttccgcatctggaatgct cagctcatccggtatgctggctaccagatgccagatggcaccatcagaggggaccctgcc aacctggagttcactcagctgtgcattgacctgggctggaagccccactacggccgcttc gatgtgctgcctctggtcctgcaggctgacggccgtgacccagaactctttgaaatccca cgggatcttgtgcttgaggtgcccatggaacatcccaagtacgagtggttccaggagctg gggctgaagtggtatgccctgcccgcagtggccaacatgctgctcgaggtgggtggcctc gagttcccagggtgccccttcaatggctggtacatgggcacagagattggcgtccgggac ttctgtgatgctcagcgctacaacatcctggaggaggtgggcaggaggatgggcctggag acacacacactggcctccctctggaaagaccgcgctgtcacggagatcaacgttgctgtg ctccatagcttccagaagcagaatgtgaccatcatggaccaccactctgcagcagagtcc ttcatgaaacacatgcagaacgagtaccggacccgtgggggctgcccagctgactggatt tggctggtccctccaatgtcggggagcatcacccccgtgtttcaccaggagatgctgaac tacatcctgtccccattctactactatcaggtggacgcctggaagacccacgtgtggcag gacgagaagcggagacccaggagacgagagatcccgttcagagtcttggcgagagctgtg ctctttgcctctgtgctgatgcacaagacaatggcatcccgagtcagagccacaatcctc tttgccacggagacgggaaagtcagaagcgctggcccaggacctgggggccttgttcagc tgtgccttcaatcccaaggttctctgcatggatgagtacaggctgagcacgttggaggag gagcagctgctgctggtggtgaccagcacgtttgggaacggagactgccctggcaatgga gagacactgaagaaatccctcttcatcctgaaaaagctcaccaacaccttcaggtatgct gtgttcggccttggctccagcatgtatcctcgcttctgtgccttcgctcatgacatcgac ctgaagttgtcccagctgggggcctctcagctcaccccagtgggggaaggggatgagctc agcgggcaggaggatgccttccgcacctgggctgtgcaaaccttcaaggcagcctgtgag gcatttgatgttcgaggcaaacaccacatccagatccccaagctctacacatccaccgtg acctgggagccacaccactacaggctggtgcaggacttgcagcctttggacctcaacaaa gccctcagtaggctgcatgccaaggacgtgttcaccatgaggctcaaatctcagcagaat cttcagagtccaaaatccagccgcaccaccctcctggtggaactctcctgtgaggacagc cgaggcctggcttacctgcccggggagcaccttggggttttcccatgcaaccagccggcc ctggtccaaggcgtcttggagcgagtggtggacagcctaggagcccacaacatcatgcgc cttgaggccctggatgacagcgggagctactgggtcaaggccaagaggctgccaccctgc tcacttagccaggccctcacctacttcctggacatcaccacccccccaacccagctgcag ctccagaagctggcccggctggccacagaacaggctgagagacagagactggagactctg agccagccctcagagtacaacaaatggaagttcaccaacagccccacgttcctggaggtg ctggaggagttcccgtcgctgcgggtgcccgctgccttcctgctctcccagctccccatt ctgaagccccgctactactccatcagctcctccccggaccacactccctcagaggtgcac ctcacggtggccgtggtcgcctaccgcacccaagatgcccggggccccctgcaccgtggc gtgtgcagtacatggctcagcaacttgaagccccaggacccggtgccctgctttgtgcgg agggtcagcagcttccagctccccaaggacccctcccatccttgcatcctcattgggccc ggcacaggcatcgctcccttccgaagtttctggcagcagcgtctccacaactctgagcac aaagggctccagggtggccgaatgaccctggtgtttgggtgtcgtcacccagacgaggac cacatctataaggaggagatgctgcagatggcccggaagggggtgctgcatgaagtgcac acagcctactccaggctgcctgggaaacccaaggtctatgttcaagacatcctgcggcag cagctggctggagaggtgctccgtgtgctccacgaggagccaggccacctctatgtgtgt gggaacgtgctcatggcccaggacgtggcctacactctgaagcagctggtggctgccaag ctgaacttgaatgaggagcaggttgaggactacttcttccagctcaagagccagaagcgc tatcatgaagatatctttggtgctgtctttccctacgaggtgaagaaggaccgggcagag cggccacctggcgacatcaagctctga

DBGET integrated database retrieval system