Heterocephalus glaber (naked mole-rat): 101699733
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Entry
101699733 CDS
T02812
Symbol
Kalrn, Kalirin
Name
(RefSeq) kalirin, RhoGEF kinase
KO
K15048
kalirin [EC:
2.7.11.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101699733 (Kalrn)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hgl04131
]
101699733 (Kalrn)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hgl04147
]
101699733 (Kalrn)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101699733 (Kalrn)
Protein kinases [BR:
hgl01001
]
Serine/threonine kinases: CAMK group
Trio family [OT]
101699733 (Kalrn)
Membrane trafficking [BR:
hgl04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
101699733 (Kalrn)
Exosome [BR:
hgl04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
101699733 (Kalrn)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RhoGEF
SOS1_NGEF_PH
Pkinase
SH3_KALRN
Spectrin_6
Spectrin
SH3-RhoG_link
PK_Tyr_Ser-Thr
I-set
PH
fn3
Ig_3
CRAL_TRIO_2
ig
FN3_DSCAM-DSCAML_C
SH3_1
IQ_SEC7_PH
Spectrin_SESTD1
PH_10
SH3_2
PH_19
CRAL_TRIO
Ig_2
SH3_9
V-set
DUF7799
Pur_ac_phosph_N
T4_Rnl2_C
Motif
Other DBs
NCBI-GeneID:
101699733
NCBI-ProteinID:
XP_004835268
UniProt:
A0AAX6NRC6
LinkDB
All DBs
Position
Un
AA seq
2987 aa
AA seq
DB search
MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
PARSNHDRIRQDDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHALDLQTQHNHFAMN
SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPTE
ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIM
EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
QKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
QALDWIQETGEYYLSTHTSMGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
KASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKQRNNSKRDGVEDIDSQGD
GSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELSIQVGQTVELLERPS
ERPGWCLVRTTERSPPQEGLVPSSTLCISHSRSSVEMDCFFPLVKDAYSHSSSENGGKSE
SVANLQGQPSLNSIHSSPGPKRSTNTLKKWLTSPVRRLNSGKADGNIKKQKKVRDGRKSF
DLGSPKPGDETTPQGDSADEKSKKGWGEDEPDEESHTPLPPPMKIFDNDPTQDEMSSSLL
AARQASTEVPTAADLVSAIEKLVKSKLTLEGGSYRGSLKDPTGCLNEGMTPPTPPRNLEE
EQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEAFMKRIEEKGVPEDMRGKDKIVFGNIH
QIYDWHKDFFLGELEKCIQEQDRLAQLFIKHERKLHIYVWYCQNKPRSEYIVAEYEAYFE
EVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGLECTDIEKAVELMCLVPKR
CNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELL
RKGSLTPGYMFKRSIKMNYLVLEENVDNDPCKFALMNRETSEKVILQAANSDIQQAWVQD
INQVLETQRDFLNALQSPIEYQRKERSTAVIRSQPARVPQVSPRPYSSVPVGSEKPPKGS
SYNPPLPPLKISTSNGMPGFDCHQPGDKFESSKQNDLGGCNGTSSMAVIKDYYALKENEI
CVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLSKPTAAAESSDGSIKK
SCSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSME
ILNPNFIQEVAPEFLMPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNNSA
SYSVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQE
RSCTSVILRWLPPASTGNCTISGYTVEYREEGSQVWQQSVASTLDTYLVIEDLSPGCPYQ
FRVSASNPWGISLPSEPSEFVRLPEYDAAADGATISWKENFDSAYTELNEIGRGRFSIVK
KCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYVTLHDTYESPTSYILILEL
MDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPR
VKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSP
FLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQ
PHNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRVNQGT
NT seq
8964 nt
NT seq
+upstream
nt +downstream
nt
atgacggaccgcttctgggaccagtggtatctctggtatctccgcttgctccggctgctg
gatcgaggatcttttcggaatgatggtttgaaagcttctgatgtccttcccatcctaaag
gaaaaagtggccttcgtgtctgggggccgtgataagcgaggtggacccatcttgaccttc
cctgctcgaagcaatcatgacagaataagacaggatgacctgcggaaacttgtgacgtat
ttggccagtgtgccaagtgaggacgtgtgcaaacgtggcttcaccgtcatcatcgacatg
cgaggctccaagtgggacctcatcaagcccctcctcaaaacgctgcaagaagcatttcca
gccgagatccatgtggccctcatcatcaagccagataacttctggcagaaacagaagacc
aactttggcagctctaaattcatctttgagacgagcatggtgtctgtggagggcctcacg
aagctggtggatccctctcagctgacagaagagtttgatggctctctggactacaaccac
gaggagtggattgagctgcggctctccttggaggagttcttcaacagcgcagtgcacctg
ctgtcacgccttgaggacctgcaggagatgctggctcggaaggagttccccgtggatgtg
gagggctctcggcggcttatcgatgagcacacgcagcttaagaaaaaggtgctgaaggcc
cctgtggaagagctggaccgggaggggcagcggctgctgcagtgcatccgctgcagtgat
ggcttctcagggcgcaactgcatcccgggcagtgctgacttccagagcctggtgcctaag
atcacgagcctcctggacaagctacactccacccggcaacacctgcaccagatgtggcat
gtgcgcaaactcaagctggaccagtgcttccaactgcggctctttgagcaggatgctgag
aagatgtttgactggataagccacaacaaggaattatttctccagagccacacggagatt
ggagtcagctaccagcatgccctagacctccagacacagcacaatcacttcgccatgaac
tccatgaatgcttatgtcaacatcaaccgcatcatgtccgtggcttcccgcctctctgag
gctggccattatgcctcccagcaaatcaagcagatctccacacagctggaccaggagtgg
aagagctttgccgctgctctggacgaacgtagcaccatcctggccatgtctgctgtgttc
caccagaaggctgagcagttcctgtctggagtggatgcctggtgcaagatgtgcagtgaa
ggtggcctgccatctgagatgcaagacctggaactggcaatccaccaccatcagaccttg
tacgagcaggtgacccaggcctacacagaggtcagccaggatggtaaagcactgctggat
gtgttacagcgtcccttgagtcctgggaactctgagtccctcacagccacagctaactac
tccaaggcagtgcaccaggtgctggatgtggtgcatgaggtgctgcaccaccagcggcgg
cttgagagcatctggcaacaccgcaaggtgcgactccaccagcggctgcagctctgtgtc
ttccagcaggatgtgcagcaggtgttggactggattgaaaaccatggtgaagcctttctc
agcaaacacactggggttggaaaatccctgcatcgagctcgagccctgcagaagaggcat
gatgactttgaagaggtggctcagaatacgtacaccaatgccgacaaactcctagaagca
gcggagcagttggctcagaccggcgaatgtgacccagaggagatctacaaagcagctcga
cacctggaggtgcgcatccaggacttcgtgcgcagggtagagcagcggaagcttctccta
gacatgtctgtctccttccacacacacaccaaagagttgtggacatggatggaggaccta
cagaaggagatgctggaggatgtctgtgcggactctgtggatgcagtccaggaactgatc
aagcagttccagcagcagcagactgccaccctggatgccaccctcaacgtcatcaaagaa
ggcgaagaccttatccagcagctcaggtcagcgcctccctccctgggggagcccaccgag
gccagggactcagctgtgtccaacaacaaaacaccacacagtagctccatcagccacatc
gagtcagttctacaacagctggatgatgcccaggtgcagatggaggagctgtttcatgag
cggaagatcaagctggacatcttcctgcagttgcgcatctttgagcagtacaccattgag
gtgacagcagagctggatgcctggaatgaggacttgctcaggcaaatgaatgacttcaac
acagaggatctgaccctggcagagcagcggctgcagcgccacacagagcggaaactagcc
atgaacaacatgacctttgaggtcatccagcagggccaggatctgcaccagtatatcatg
gaggtccaggcctcaggaattgaattaatctgtgaaaaagacattgatctggcagcccag
gtgcaagagctactggagtttctccacgagaagcagcatgaattggagctcaacgcagag
cagacccacaagcggctagagcagtgtctccaactgcgacacctccaggccgaggtcaaa
caggtcctgggatggatacgtaatggagagtccatgctcaatgctagtctggtaaatgcc
agctctttgtcggaggcagagcagctgcagcgggagcacgagcagttccaactagccatc
gagtccctctttcatgccacttccttgcagaagacgcaccagagtgccctgcaggtgcag
cagaaagctgaggcactgctccaggctggccactatgatgcagatgccatccgggaatgt
gccgagaaggtagccctccactggcagcagctcatgctgaagatggaagaccgactcaaa
ctggtcaatgcctctgtggccttttacaaaacttctgaacaggtgtgcagtgtcctggag
agcttagagcaagaatatcggagagacgaggattggtgcggtggacgagataaactgggg
ccagcagcagagatcgaccatgtcattccactcatcagcaaacacttggaacaaaaggaa
gcttttcttaaggcctgtaccctggcacggcggaatgctgaagtgtttctcaagtacatc
cacaggaacaatgtcagcatgcccagtgtcgccagccacacccggggccctgagcagcaa
gtgaaagccatcttgagcgagctcttacagagggaaaatcgtgtcctgcatttctggacc
ttgaaaaagaggcggttagaccagtgccagcaatatgtggtgtttgagcgcagtgccaaa
caggcactggactggatccaagaaacgggtgaatattacctctcaacacatacctccatg
ggagagaccacagaggagactcaggagctactaaaagaatatggagaattcagggtgcct
gccaagcaaacaaaggagaaggtgaagcttctgattcagctggctgatagctttgtagaa
aaaggccacattcatgccacagagataaggaaatgggtgaccacagtggacaaacactat
cgggatttctctttgaggatggggaagtaccgatactccctggagaaagccctaggagtc
aacacagaggataacaaggacctggagctagacatcataccagcaagcctttccgatcgt
gaggtcaagcttcgggatgccaaccatgaagttaatgaagagaagcgaaagtcagcccga
aagaaagaattcattatggctgaactccttcagaccgagaaagcttatgtaagggactta
catgagtgcttggagacttacctgtgggaaatgaccagtggtgtggaagagatcccccct
gggatccttaataaagagcatatcatctttggcaacatccaggagatctacgattttcat
aacaacattttccttaaagagctggagaagtatgagcagctgcctgaggatgtgggacac
tgctttgtcacctgggcagacaaatttcaaatgtatgtcacctactgtaaaaacaagcct
gattccaaccagctgatcctggagcatgcaggcaccttctttgatgagatccagcagcgg
catggtctggctaactccatctcttcctacctaattaagcctgtgcagaggatcaccaaa
taccaactgctcctgaaggaacttttaacttgctgtgaagaagggaaaggggagctcaag
gatggcttggaggtgatgctcagtgtccccaagaaagccaatgatgccatgcatgtcagc
atgctggaagggttcgatgagaacctggacgtacagggggaattgattctccaggatgcc
tttcaagtgtgggacccgaaatcactgatccggaagggacgggagcggcacttgttcctc
tttgaaatctccttagtttttagcaaggagatcaaagattcttcaggacacacgaaatat
gtttacaagaacaagctactgacctcagagctgggtgtgaccgagcacgtagagggcgac
ccctgcaaatttgccttgtggtctggccgcaccccatcctcagacaataaaacagtgctc
aaagcttccaacattgaaaccaagcaggagtggatcaagaacattcgagaagtgattcaa
gaaaggattattcacctaaaaggagctttaaaggagccaattcagctccccaaaacacca
gccaaacagaggaacaatagtaagagggacggagtggaggatattgacagccagggggat
gggagcagtcagccagacaccatctccattgcatctaggacctctcaaaacacagtggac
agtgacaagctctccggtggatgtgagttgaccgtcgtcctccaggacttcagtgcaggc
cacagcagcgagctgagcatccaggtgggacagacagtggagctgctggagcggcccagc
gagaggccaggctggtgtctggtccgcaccacagaacgaagcccacctcaggagggcctg
gtccccagcagcaccctgtgcatctcccattcacgaagcagcgtggagatggactgcttc
ttccctttggtgaaagatgcgtattctcattcctccagtgaaaacgggggcaagtctgag
tctgtggccaacctgcagggccagccttctctcaactccatccacagttcccctggtccc
aagcgctccaccaacacccttaagaagtggctgacaagtcccgtgcgtcggctcaacagt
gggaaagcagatggaaacatcaaaaagcagaagaaagtacgagatggtcggaagagtttt
gacctgggatctccaaaacctggggatgagacgaccccacagggagacagtgctgatgag
aagagcaagaaaggttggggtgaagatgagccagatgaagagtcgcacactcccctccct
ccacctatgaagatctttgacaatgaccccacccaggacgagatgtcctcctctttgtta
gcagcccggcaggcttccactgaagtacctactgctgcagaccttgtcagtgcaatagaa
aagttggtcaaaagcaagctgactctagaaggaggctcctaccgagggagtctaaaagac
cccacaggctgcctgaatgaggggatgaccccgcctacacctcctagaaacctggaagaa
gaacagaaagccaaggccctgagaggcaggatgtttgtcctgaatgagctggtacagaca
gagaaagactatgtcaaggacctgggaattgtggtggaggccttcatgaagaggatagag
gagaagggtgtccctgaggatatgcgagggaaggataaaattgtgtttggaaatatccac
cagatctatgactggcataaggacttcttcctgggtgaactggaaaaatgtatccaagaa
caagatagactggcccagctctttattaaacatgaacggaagctgcacatctatgtgtgg
tactgccagaacaagccacgctctgagtacattgtggctgaatatgaagcctacttcgag
gaggtaaaacaggagataaatcaaaggctgacactgagtgacttccttatcaagcccatt
cagagaataacaaaataccagttgctcctcaaggacttcctgagatacagtgagaaggct
ggtttggagtgtacagatattgagaaagcagtggagttaatgtgccttgttcccaaacgt
tgcaatgacatgatgaatctgggacgcctacaaggctttgagggcaccctcactgcccag
ggcaagctgctgcagcaggacacgttctatgtgatcgagctggacgctggcatgcagtct
cggaccaaggagaggcgtgtgttcctctttgagcagatcgtaatcttcagtgaactgctc
aggaaggggtccctcaccccgggctacatgttcaaaaggagcatcaagatgaattacttg
gtcttggaggagaatgtggacaatgacccttgcaaatttgcactcatgaacagggagact
tctgagaaggtcattctgcaagctgccaactcagacatccagcaggcctgggtacaggac
atcaatcaagtcctagaaacacagcgagacttcttaaatgcactacagtcacccattgag
tatcagcggaaagaacggagcacagccgtgattcggtcccagcctgctagggttccccaa
gtcagccccaggccctactcctctgtccctgtgggctctgagaagcctccaaagggctcc
agctacaatccacctttgccaccgttgaagatatctacctccaatggcatgccagggttc
gactgccaccaacctggcgacaagtttgagtctagcaagcagaacgacctggggggctgc
aatgggacctcgtctatggctgtgatcaaagattactatgcactgaaggaaaatgaaatc
tgtgtgagccaaggggaagtggtccaggtcctagccgtcaatcagcagaacatgtgcctg
gtgtaccagcctgccagcgaccattcacccgcagctgagggctgggtcccaggcagcatc
ctggctcccctcagcaaacccacagcagcagcagaaagtagtgatggcagcatcaagaag
tcatgttcatggcatactctacgcatgagaaagcgggcggaagtggagaacacgggtaaa
aatgaagccacagggcctcgtaaacccaaggatattctgggcaacaaagtctctgttaaa
gagacgaacagttccgaggagtcagagtgtgatgatcttgaccctaatactagcatggag
atcttaaatccaaatttcatccaagaagtggccccagaattcctcatgcccttagtggac
gtgacctgcttgctcggggacacagtgatactgcagtgcaaagtctgtgggcggccaaag
cccaccatcacctggaagggtccagaccagaacatcctggacactgacaacaactcggcc
tcatacagtgtctcctcctgtgactctggggaaatcaccctgaagatctgcaatctgatg
cctcaggacagtgggatttatacctgcatagccacaaatgaccatgggaccacatccaca
tctgctacagtcaaggtgcaaggtgttcctgcagctcccaaccgccccatcgcccaggag
aggagctgcacctctgtgattctccgctggctgcccccagccagcacggggaactgcacc
atctcaggatataccgtggagtaccgggaggaaggttcccaggtctggcagcagtcggtg
gcttcgaccttggacacttacctcgtcatcgaagaccttagtcctgggtgtccttatcag
ttcagagtcagtgccagcaacccttggggaatcagccttcccagcgaaccctcggagttt
gtgcgacttccagagtatgatgcggctgctgatggagccaccatttcttggaaggaaaat
tttgactctgcttatactgagctgaatgagattggaagaggccgattttctatagtgaag
aaatgcattcacaaagctacccggaaagatgttgctgtgaaatttgtgagcaaaaaaatg
aagaagaaggagcaggctgcccacgaggctgcactgctgcagcacctgcagcaccctcag
tacgtcacactgcacgacacctatgagtcccccacgtcctacatcctgatcttggaactg
atggatgatggccggctcttagactaccttatgaatcatgacgaattgatggaggagaaa
gtagctttctacatccgggacatcatggaggctctgcagtaccttcacaactgcagggtt
gcacacctggacataaagcctgagaacctgctcattgaccttcggattccagtgcctcga
gtgaagctcattgacttggaagatgctgtccagatctcaggccacttccacatccaccac
ctgctggggaatcccgagttcgctgccccagaagtgatccaaggcatccccgtctccctg
ggcacagatatctggagcatcggggttctgacctatgtcatgctgagcggggtctcgccc
ttcctggatgaaagcaaagaggagacgtgcatcaacgtgtgcagggtggatttcagcttc
ccccacgagtacttctgtggtgtgagcaatgccgccagagatttcatcaatgtgatctta
caggaagacttccgccggcggcccacagcagccacttgcctgcagcacccgtggctgcag
ccacacaatggcagctactccaagatccccctggacacctcccgcctggcctgcttcata
gagcgccgcaagcaccagaatgatgtgcgtcctattcccaatgtcaagagctacattgtc
aacagagtgaaccaagggacatag
DBGET
integrated database retrieval system
