Heterocephalus glaber (naked mole-rat): 101701016 Help Entry 101701016         CDS       T02812                                  Symbol Pklr Name (RefSeq) pyruvate kinase, liver and RBC   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00010   Glycolysis / Gluconeogenesis hgl00620   Pyruvate metabolism hgl01100   Metabolic pathways hgl01200   Carbon metabolism hgl01230   Biosynthesis of amino acids hgl04910   Insulin signaling pathway hgl04930   Type II diabetes mellitus hgl04932   Non-alcoholic fatty liver disease hgl04950   Maturity onset diabetes of the young Module hgl_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hgl_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     101701016 (Pklr)    00620 Pyruvate metabolism     101701016 (Pklr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101701016 (Pklr)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101701016 (Pklr)    04950 Maturity onset diabetes of the young     101701016 (Pklr)    04932 Non-alcoholic fatty liver disease     101701016 (Pklr)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hgl04147]     101701016 (Pklr) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      101701016 (Pklr) Exosome [BR:hgl04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    101701016 (Pklr) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Motif Other DBs NCBI-GeneID:  101701016 NCBI-ProteinID:  XP_012923451 UniProt:  A0AAX6QN50 LinkDB All DBs Position Un AA seq 573 aa AA seqDB search MSIPNLLPQQLCSWIPQTQRDLAKSVLIGAPGGPAGYLRRASVAQLTQELGTTFFQQQQL PAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMDIARLNFSH GSHEYHAASIANIREAAESFASSPLIYRPVGIALDTKGPEIRTGILRGGPESEVEIVKGA RVLVTVDSAFRTRGDADTVWVDYSNIARVVPVGGRIYIDDGLICLVVRKIGPEGLLTEVE SGGVLGSRKGVNLPGAEVDLPSLSEQDAKDLRFGVEHGVDIIFASFVRKASDVAAVRAAL GPEGQGIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCN LAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQ HAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTSGRSA QLLSRYRPRAAVIAVTRSAQAARQIHLCRGVFPVLYREVPEAIWADDVDRRVQFGIESGK LRGFLSAGDLVIVVTGWRPGSGYTNIMRVLSIS NT seq 1722 nt NT seq  +upstreamnt  +downstreamnt atgtcaattcccaaccttctgccccagcagctttgctcatggatcccacagacccaaagg gacctcgccaagtctgtcctcatcggtgccccaggagggccagcagggtacctgcggcgc gccagtgtggcccagctgacccaggagctgggcaccaccttcttccagcagcagcagctg ccagcagccatggctgacaccttcctggaacacctctgcctgcttgacatcgactcagag ccagtggccgctcgcagcaccagcatcattgccaccatcgggccggcatctcgatccgtc gagcgcctcaaggagatgatcaaggccgggatggacatcgctcgactcaatttctcccac ggatcccacgagtaccacgccgcgtccatcgctaacatccgggaggcagcagagagcttc gcgagctccccgctcatctacaggcccgtgggtatcgctttggacaccaaggggcccgag atccgcactgggatcctgcgagggggcccggagtcggaagtggagattgtgaagggcgcc cgggtgctggttactgtggactcggccttccggactcggggggacgcggacaccgtgtgg gtggactactccaacatcgcccgggtcgtgccggtggggggccgcatctacatcgacgac ggcctcatctgccttgtggtccggaaaatcggccccgaggggctgctgaccgaggtggag agcggcggcgtcctaggcagcaggaagggcgtgaacctgcccggcgccgaggtggacctc cctagcctgtccgagcaagatgccaaggacctgcgcttcggggtggagcatggggtggac atcatcttcgcctccttcgtgcggaaagccagcgacgtggctgctgtgcgggcggccctg gggccggaaggacagggcatcaaaatcatcagcaaaatcgagaatcatgaaggcgtgaag aagtttgatgaaatcctggaggtgagcgatggcatcatggtggcacgaggtgatctgggc atcgagatcccggccgagaaggttttcctggctcagaagatgatgattgggcgctgcaac ttggcgggcaagcccgtggtctgtgccacacagatgctggagagcatgatcaccaagccc cggccaactcgggcagagaccagcgacgtggccaacgccgtgctggacggggctgactgc atcatgttgtcaggggagaccgccaagggcaacttcccggtggaggccgtgaagatgcag cacgcgattgctcgggaggcagaggccgcagtgtaccaccggcagctgtttgaggagcta cgccgggcagcaccactgagccgtgaccccactgaggtcaccgccatcggcgctgtggag gctgccttcaagtgctgcgctgctgccatcatcgtgctgaccacctctggccgctcagcc cagcttctgtctcggtaccgccctcgtgcagcggtcatcgctgtcacccgctctgcccag gctgctcgccagatccacctgtgccggggagtcttccccgtgctctaccgtgaggttccg gaggccatctgggcagatgatgtggatcgccgggtccagtttggcatcgaaagcggaaag cttcgtggcttcctcagcgcaggggatctggtgattgtggtgacgggctggcggcctggc tctggctacaccaacatcatgcgggtgctgagcatctcctga

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