Heterocephalus glaber (naked mole-rat): 101701301 Help Entry 101701301         CDS       T02812                                  Symbol Gsk3b Name (RefSeq) glycogen synthase kinase 3 beta   KO K03083   glycogen synthase kinase 3 beta [EC:2.7.11.26] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl04012   ErbB signaling pathway hgl04062   Chemokine signaling pathway hgl04110   Cell cycle hgl04150   mTOR signaling pathway hgl04151   PI3K-Akt signaling pathway hgl04310   Wnt signaling pathway hgl04340   Hedgehog signaling pathway hgl04360   Axon guidance hgl04390   Hippo signaling pathway hgl04510   Focal adhesion hgl04550   Signaling pathways regulating pluripotency of stem cells hgl04657   IL-17 signaling pathway hgl04660   T cell receptor signaling pathway hgl04662   B cell receptor signaling pathway hgl04722   Neurotrophin signaling pathway hgl04728   Dopaminergic synapse hgl04910   Insulin signaling pathway hgl04916   Melanogenesis hgl04917   Prolactin signaling pathway hgl04919   Thyroid hormone signaling pathway hgl04931   Insulin resistance hgl04932   Non-alcoholic fatty liver disease hgl04934   Cushing syndrome hgl04935   Growth hormone synthesis, secretion and action hgl04936   Alcoholic liver disease hgl05010   Alzheimer disease hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05135   Yersinia infection hgl05160   Hepatitis C hgl05162   Measles hgl05163   Human cytomegalovirus infection hgl05165   Human papillomavirus infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05200   Pathways in cancer hgl05210   Colorectal cancer hgl05213   Endometrial cancer hgl05215   Prostate cancer hgl05217   Basal cell carcinoma hgl05224   Breast cancer hgl05225   Hepatocellular carcinoma hgl05226   Gastric cancer hgl05415   Diabetic cardiomyopathy hgl05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     101701301 (Gsk3b)    04310 Wnt signaling pathway     101701301 (Gsk3b)    04340 Hedgehog signaling pathway     101701301 (Gsk3b)    04390 Hippo signaling pathway     101701301 (Gsk3b)    04151 PI3K-Akt signaling pathway     101701301 (Gsk3b)    04150 mTOR signaling pathway     101701301 (Gsk3b)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     101701301 (Gsk3b)   09144 Cellular community - eukaryotes    04510 Focal adhesion     101701301 (Gsk3b)    04550 Signaling pathways regulating pluripotency of stem cells     101701301 (Gsk3b)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     101701301 (Gsk3b)    04657 IL-17 signaling pathway     101701301 (Gsk3b)    04662 B cell receptor signaling pathway     101701301 (Gsk3b)    04062 Chemokine signaling pathway     101701301 (Gsk3b)   09152 Endocrine system    04910 Insulin signaling pathway     101701301 (Gsk3b)    04917 Prolactin signaling pathway     101701301 (Gsk3b)    04935 Growth hormone synthesis, secretion and action     101701301 (Gsk3b)    04919 Thyroid hormone signaling pathway     101701301 (Gsk3b)    04916 Melanogenesis     101701301 (Gsk3b)   09156 Nervous system    04728 Dopaminergic synapse     101701301 (Gsk3b)    04722 Neurotrophin signaling pathway     101701301 (Gsk3b)   09158 Development and regeneration    04360 Axon guidance     101701301 (Gsk3b)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101701301 (Gsk3b)   09162 Cancer: specific types    05210 Colorectal cancer     101701301 (Gsk3b)    05225 Hepatocellular carcinoma     101701301 (Gsk3b)    05226 Gastric cancer     101701301 (Gsk3b)    05217 Basal cell carcinoma     101701301 (Gsk3b)    05215 Prostate cancer     101701301 (Gsk3b)    05213 Endometrial cancer     101701301 (Gsk3b)    05224 Breast cancer     101701301 (Gsk3b)   09172 Infectious disease: viral    05160 Hepatitis C     101701301 (Gsk3b)    05162 Measles     101701301 (Gsk3b)    05163 Human cytomegalovirus infection     101701301 (Gsk3b)    05167 Kaposi sarcoma-associated herpesvirus infection     101701301 (Gsk3b)    05165 Human papillomavirus infection     101701301 (Gsk3b)   09171 Infectious disease: bacterial    05135 Yersinia infection     101701301 (Gsk3b)   09164 Neurodegenerative disease    05010 Alzheimer disease     101701301 (Gsk3b)    05020 Prion disease     101701301 (Gsk3b)    05022 Pathways of neurodegeneration - multiple diseases     101701301 (Gsk3b)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101701301 (Gsk3b)    05415 Diabetic cardiomyopathy     101701301 (Gsk3b)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101701301 (Gsk3b)    04932 Non-alcoholic fatty liver disease     101701301 (Gsk3b)    04931 Insulin resistance     101701301 (Gsk3b)    04934 Cushing syndrome     101701301 (Gsk3b)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101701301 (Gsk3b)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hgl01001]     101701301 (Gsk3b)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hgl03036]     101701301 (Gsk3b) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.26  tau-protein kinase      101701301 (Gsk3b) Protein kinases [BR:hgl01001]  Serine/threonine kinases: CMGC group   GSK family [OT]    101701301 (Gsk3b) Chromosome and associated proteins [BR:hgl03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     101701301 (Gsk3b) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH Motif Other DBs NCBI-GeneID:  101701301 NCBI-ProteinID:  XP_004835712 UniProt:  A0A0P6JAL8 LinkDB All DBs Position Un AA seq 433 aa AA seqDB search MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRGQ TNNAASASASNST NT seq 1302 nt NT seq  +upstreamnt  +downstreamnt atgtcggggcggccgagaaccacctcctttgcggagagctgcaagccagtgcagcagcct tcagcgtttggcagcatgaaagttagcagagacaaggatggcagcaaggtgaccacagta gtggcaactcctgggcagggtccagataggccacaagaagtcagctatacagacactaaa gtgattggaaatggatcatttggtgtagtatatcaagccaagctttgtgattcgggagaa ctggtggccatcaaaaaagtattgcaagacaagaggtttaagaaccgagagcttcagatc atgagaaagctagatcactgtaacatagtccgattacgttacttcttctactccagtggt gagaagaaagatgaggtctaccttaatctggtgctggactatgttccagaaactgtgtac agagttgccagacactatagtcgagccaaacagacgctccctgtgatctatgtcaagttg tatatgtatcagctgttcagaagtttagcctatatccattcctttggaatctgccatcgg gatattaaaccacagaacctcttgttggatcctgatacagctgtattaaaactctgtgac tttgggagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg tactatagggcaccagagttgatctttggagccactgattatacatctagtatagatgtg tggtctgcaggctgtgtattggctgagctgttgctaggacaaccaatatttccaggggac agtggtgtggatcagttggtagaaataatcaaggtccttggaacaccaacaagggagcaa attagagaaatgaacccaaattacacagaattcaaattccctcaaattaaggcacatcct tggacaaaggattcgtcaggaacaggacatttcacctcaggagtacgggtcttccgaccc cgaactccaccagaggcaattgcactgtgtagccgtctgctggagtatacaccaactgcc cgactgacaccactggaagcttgtgcacattcatttttcgatgaattacgggacccaaat gtcaaactaccaaatgggcgagatacacctgcactcttcaactttaccactcaagaactg tcaagtaatccacctctggctaccatccttattcctcctcatgctcggattcaagcagct gcttcaacccctacaaatgccacagcagcctcagatgctaatgctggagaccgtggacag accaataatgctgcttctgcatcagcttccaactccacctga

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