Heterocephalus glaber (naked mole-rat): 101701583
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Entry
101701583 CDS
T02812
Symbol
Spg11, Spatacsin
Name
(RefSeq) spastic paraplegia 11 (autosomal recessive)
KO
K19026
spatacsin
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl05014
Amyotrophic lateral sclerosis
hgl05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
101701583 (Spg11)
05022 Pathways of neurodegeneration - multiple diseases
101701583 (Spg11)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hgl03400
]
101701583 (Spg11)
DNA repair and recombination proteins [BR:
hgl03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Other HR factors
101701583 (Spg11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Spatacsin_C
Motif
Other DBs
NCBI-GeneID:
101701583
NCBI-ProteinID:
XP_004861775
UniProt:
A0AAX6PYC0
LinkDB
All DBs
Position
Un
AA seq
2443 aa
AA seq
DB search
MAAAGPRAGNAASAGRSCRAEAMACVLPMLLVPVPAEATGRLGLRAQLHRKQEALGSLTP
AGSLQVLSLVPGGPRGGSCGLQGPFQQFTWEDFDNGSTPTHKPKLLALSENYELLIYEFN
LEDGRCDSAVLYSCSVKTLQKLVEDQGVSISLLSLRILSFHNNTSVLFINKCIILHVVFP
ERDAEIRVLSCFTLPLPVQTVDTIIDSQLCRGILFVLSSLSWIHIFDTVNGTYVAYVDLA
LHQEDMYNEQQQEPAKISSFTSMKVSPDLDVIVIVSSNSAVALNLNLYFRQHPGYLLCKR
TLEDLPVQGLKGIDEDDPVNSVHSMKLTKFSFQVDRSWNAQLLSLNERIKSSKLEISCCA
PWFQDILHLESPKSGNRGTSVSSWVFVSQDIMRDQYNLPQKDHAQTSDPGRFWKIMHLSE
QEEPTELNCVSVTGFTALFTWAVEMSDKYTILLWDLETQGLQCFSLGQKCIPVDSSGDQQ
LCFVLMENGLSLILFGLTQEEFLNRLMIHGSASIVDTLCHLNGWGRCSIPVHALEAGIEN
RQLDTVDFFLKSKGNLFTASSESSVPDRFDHFPSQLYLRNVEELTPALDLLCSAIKENDS
ETQSKQFSEQLLTLTLSFLNKQIKELFIHTKELDEHLQKGVNILTSYINDLRTFMIKFPW
KLTDAIDEYDVNENIPTVKESTIWEKLSFEEVIASAILHNKIPEAQTFFRMNNHSAQRLE
ELIRIGLDLVFVNLKKNNIKEASELLKNMGFDVKDQLLKICFYTTDKNIQNFLVEILKEK
NFLSEKEKRTIHFVHQVEKFYSGYLQENMQIQSFPRYWIKGQDFFKYKSVLDSFLKYDHK
DEFNKQDHKIALNWAQWWDQPTEEYMLLPRISPEEYKSYSPETLWRYLTAHHDWLSITLW
IGEFQTQENYMSLQQNKWPPLTSDVIDQNTCCNNYMKNAILDKLARNGIFLASELEDFEL
LLLRLSRTGGVIQDTLPVQNYKTKEGWDFHSHFILYCLEHGLQHLLYVYLDCYELNPENC
PFLEKKELHEAYPWFEFLVQCQQVSSNLTDPKLIFHASLANAQILIPTNQASISSMLLEG
HTLLALATTMYAPGGASQVVQNEENENCLKKVDPQLLRMALTPYPKLKAALFPQCTAPSV
LPSDITLYHLIQSLSPFDPSRLFGWQSTNTLAIGDALSHLPHFSSPCLVNKYAVVERLNF
AYYLHHGRPSFAFGTFLVQELTKSKTPKKLIQQAGKEACILGLSSFHIPSIGAACVCFLE
LLGLDSLKLRVDMKVANIILSYKCRNGDTQYSFIQETLAEKLSKLADDEKATTEELLVLL
EEGTWHSIQHQEIKRLSSESESQWALVVQFGRLHHTKLSTSYLRECAKANDWLQFLIHSQ
LHDFQPEEVKPLLQCFSPVLQDHLQLAFENLSSVSNSRVDSDQVSTRSPQKLQRNREEKT
NFFEVLLLCAAKPDSWRWLLAEAVRHKAPVLSVLASCLQDASAVPCLCVWIITSVEESIA
TEVRGHNRGLTENYTWDLEDLSIVWRTLLTRQKSRTLIRGFQLFFKESPLLLMMEVYELC
MFFKNYKEAKAKLLEFLKSLKKLDTATTRVHPVLPAAWLRDQVCFLLKLMPQQCQTQYEL
GKLLQLFVGTEHLFSDDPDIKKLCVLSQILKDTSIPINHTVITSYSIEIFQHECRSILER
LQTDGQFALARRIAELAELPVDNLVIEEITQEMQALKHVKQWSLKRARIDFWKKCHETFK
KNSISNKAASSFFFSQAQMACDHSAGRGSTEERHLLLILAGHWLAQEDPVPLDKLEELEK
QIWVCRITQHTLQGQQQEAEPRFSQQISTSGELSLDSLASEFSFSKLAALNTSKYLELHG
LPNIETCESRLDWKEQESLNFLIERLLDDGHVHEASRACRYFHLYNRDVTLVLHCQALAS
GEASVDDLHPEIRAVLQSAELHEEEEEPDIPGKVQSTSSVDSQSCVMVPPSDEVVTNLET
LTSKCLYGKNYCRQILCLYELAKELGCSYTDVAAQGGKALLHAILASQQPDRCRRAQAFI
STQGLPPDTVAELVAEEVMQELLTSSEGTGHKQVFSPAEESQTFLQLTALCQDHTLVGMK
LLDKISSVPNGQLSCTTELLILAHHCFTLTCHMEGIMRVLQAARTLTDNHLAPNEEYGLV
VRLLTGIGRYNEMTYIFDLLHQKHYFEVLMRKKLDTSGTLKTALLDYIKRCRPGDSEKHN
MIALCFSMCREIGENHEAAAYIQLKLIECQAWEDNLKDGQQLKQLLLKALTLMLDAAESY
AKDSCVRQALHCHRLTKLITLQIHFLNTGHNTMVINLGRQKLMDCITALPRFYQASIVAE
AYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLRPSIFEEISKKCKHQPTDTVTENLKK
LLSYCEDIYLHYKLAYEHKFYEIVNVLLKDPQTGCCLKDMLAG
NT seq
7332 nt
NT seq
+upstream
nt +downstream
nt
atggccgccgccgggccgcgcgccgggaacgcggcttcagcaggccggagttgccgcgca
gaggccatggcgtgtgtcctacctatgctgttggtgcctgtgcctgctgaggcgacgggg
cgcctggggctccgggcgcagctgcacagaaagcaggaggccctcgggagtctgacaccc
gcgggcagccttcaggtgctttccttggtgccgggcggcccgcgcgggggcagctgcggc
ctccagggccccttccagcagtttacgtgggaggattttgataacggcagcacaccaaca
cacaagcccaaattgcttgctcttagtgaaaattatgaactgcttatctatgaatttaat
ttggaagatggaagatgtgattcagctgtattgtacagctgtagtgtaaagactctgcaa
aagctcgttgaagatcaaggtgtcagtatttccttactgtctttgagaattctgtcattt
cacaataacacatcagtactgttcatcaacaaatgtatcatcctacatgttgtgtttcct
gagagagacgctgagattagagtactcagctgttttacattacccttgcctgtacagaca
gtggacaccatcattgactcgcagctctgcagaggaattctctttgttttgagtagttta
agctggatccatatttttgacactgtgaatggcacatatgtagcttatgtggatttagca
cttcaccaagaagatatgtacaatgaacagcaacaggagccagccaagatttcttccttt
acctcaatgaaagtgtctccagacctggatgttatagtgattgtcagctccaactctgca
gttgctcttaacttaaatttatatttcaggcaacatccaggatacttactatgtaaaaga
acattagaagaccttcctgttcaaggacttaaggggatagatgaagatgatcctgttaac
tctgtccacagcatgaaactgaccaagttttccttccaagttgataggtcttggaatgcc
cagctattatcattgaatgaaagaataaagagctccaaactagagatttcttgttgtgct
ccatggttccaggatattttacatttggagtctcctaaatctggtaatcgtggtaccagt
gtgtcaagctgggtttttgtttcacaggacataatgcgggaccagtataatcttccacag
aaagatcatgcccagaccagtgaccctggaagattctggaaaataatgcacctcagtgaa
caagaggaacccacagaacttaactgtgtgtctgtgacaggattcactgcactgtttact
tgggcagtggaaatgagtgacaagtacaccattctcctctgggatttggagacccagggg
ttgcagtgtttctctcttggccagaagtgtattcctgtagacagcagtggagaccagcag
ctgtgctttgttttgatggaaaatggactctctttgattttgtttggtttgactcaagag
gaatttttaaacagactaatgatccatggaagtgccagcattgtggacactctttgtcat
ctcaacgggtgggggaggtgctcaattcccgtacatgcactagaggccgggatagaaaat
cggcagcttgatactgtagatttcttcttgaagagcaaaggaaatctttttactgcatcc
tcagaatcttctgtacctgatcgatttgatcactttccatcccaattatatttaagaaat
gtggaagagctgacaccagctttggatttactttgttcagcaattaaagaaaatgattct
gaaacccaaagcaaacagttttcagaacagttgcttactcttacactatcgttccttaac
aaacaaataaaggagctttttattcacactaaagagctagacgaacatctacagaaagga
gtgaacattttgaccagctacattaatgatcttcgaactttcatgataaagtttccttgg
aagctaacagatgctatagacgaatatgatgtaaatgaaaatatccctacagtaaaggag
agcactatttgggagaagctcagctttgaggaagttattgctagtgctattttacacaac
aaaataccagaggcacagaccttcttcaggatgaataatcattctgctcaaagacttgag
gagctgattagaataggcctagatttggtctttgtcaatttaaaaaagaacaatataaag
gaagcctctgagcttttgaagaatatgggctttgatgtaaaagaccagctgctgaagata
tgtttctatacaactgataaaaatattcagaactttttggttgaaattttaaaagaaaaa
aattttctttctgaaaaagagaaaagaactatacactttgtacatcaagttgaaaagttt
tattcgggatacctccaagaaaatatgcagatccagtcctttcccaggtattggataaag
ggacaagattttttcaagtacaaatctgttttggactcattcctcaaatacgatcataaa
gatgagtttaacaaacaagaccataaaattgcattaaactgggctcagtggtgggatcag
ccaacagaagaatatatgcttctccccagaataagtccagaagaatataagtcatattct
cctgaaaccctctggagatacctaacagctcatcatgattggttaagcattaccttgtgg
attggagaatttcagacccaggaaaattacatgtcacttcagcagaacaaatggccccct
ctgactagtgatgttattgatcagaatacttgctgcaacaactacatgaagaatgcaatt
ttagataagctagccaggaatgggatttttcttgcatctgaactagaagactttgaactc
ttgctcctaagactgagccgaactgggggtgtgatacaagataccctccctgttcaaaac
tacaagaccaaagagggctgggatttccattctcacttcattctctactgcttagaacat
ggtctgcagcatcttctttatgtctatcttgactgttatgaactcaatcctgaaaattgt
ccttttttggaaaagaaagaattacatgaagcttacccttggtttgaatttttagttcag
tgtcaacaagtttccagtaatttgacagatcccaaactgatcttccatgctagccttgcg
aatgctcagattttgattcccaccaatcaggccagcataagcagtatgctgttggaaggc
cataccctcctggcccttgctactacaatgtatgctcctgggggtgccagccaggttgtt
cagaatgaagaaaatgagaactgtttgaagaaagtggatccccagctactcaggatggcc
ttaactccttacccaaagttaaaagctgctctcttcccacagtgcactgctcctagtgtc
ctgccatctgatattacactctaccacctcattcagtcattgtcgccctttgatcctagc
agattgtttggctggcagtctaccaatacactagcaataggagatgcactgagtcatctc
ccacatttctctagtccttgcctggtaaataaatacgctgtagtggaacgtctgaatttt
gcttattatttacatcatggacgcccgtcatttgcatttggtacttttctggtccaggaa
ttaaccaaaagcaagactcccaagaagctgatccagcaagcagggaaggaagcctgtatc
ttagggctctcttctttccacataccttccataggagctgcctgtgtatgtttcctagaa
ttgcttggccttgacagcctcaagctcagagttgatatgaaagtggccaatataattttg
agttacaagtgtagaaatggagatactcagtacagctttatccaagagactttagctgag
aaattgtctaaactggcagatgatgaaaaggcaactacagaagaattgcttgttctctta
gaagaaggtacatggcatagcattcagcaccaggaaataaagaggttatccagtgaatct
gagagccagtgggcattagtggtacagtttggcaggctccaccatacgaaactgagcaca
tcctaccttagagaatgtgccaaagcaaatgactggctgcagttccttattcatagccag
ctccatgacttccaaccagaggaggtgaaacccctccttcagtgtttcagcccagtcctt
caagatcacttacagctggcttttgaaaacttgtcctcagtgtccaactctagagtggac
agtgatcaagtcagtaccaggtcccctcagaaacttcagagaaacagagaagagaagact
aatttctttgaagttctgctcctgtgcgcagcgaaaccagactcctggcgttggctcctg
gctgaagcagtgagacacaaagcccctgtcctcagtgtcctggcttcatgtctccaggat
gccagcgctgttccctgtctctgtgtttggatcataacctctgtggaggaaagtattgct
actgaagtaaggggacataatcggggcttgacagaaaactatacctgggaccttgaggac
ctttccatagtctggagaacattattaacaaggcagaagagcagaactcttatcagaggc
ttccagcttttctttaaggagtccccgttactgctgatgatggaggtatatgaactgtgt
atgttcttcaagaattataaggaagccaaagctaaacttctggagttcctgaaaagcctc
aaaaaacttgacacagcaactacaagagtccaccctgtcctccctgctgcatggctcagg
gaccaggtgtgtttccttttgaagcttatgccacagcagtgtcagacgcagtatgagctg
gggaagctcttacagttgtttgttggaacagagcatctcttttctgatgatccagatata
aagaagctgtgtgtccttagccaaattttgaaggatacatctatacccattaatcataca
gttattaccagctacagcattgaaatttttcagcatgaatgtagatctattttggaaaga
ctgcagacagatggacagtttgctttggccaggagaatagcagaattagctgaattacct
gtggacaacttggttattgaagagataacacaggaaatgcaggcgctaaagcacgtgaaa
cagtggtccctgaaacgagcaagaattgacttctggaaaaaatgccatgagacttttaag
aagaattccatttcaaacaaagcagcttcttcctttttcttctcccaggcccaaatggcc
tgtgatcactcagctggaagaggcagcactgaggagcgccacctgctgcttattctggct
gggcactggcttgcccaggaggaccccgtgcccttagacaagctagaggagctggagaag
cagatctgggtctgccgcatcacccagcataccctccaagggcagcagcaggaagcagag
ccgagattttctcaacagatctcaactagtggtgaactgtcccttgatagcttagccagt
gagttttccttctccaagttggctgctctgaacacatcaaaatacttggaacttcatggc
cttccaaacatagagacttgtgagagtagactggactggaaggagcaggaatcactgaac
tttctgattgagcgtctgctggatgatggccatgtgcatgaggcaagtagagcgtgccga
tattttcatctctataaccgagatgtcaccttggtgttgcactgccaagccttggcctca
ggggaagcaagtgtggatgacctgcacccagagatccgtgctgtcctacaaagtgctgag
ctgcacgaggaagaagaggagcctgacattccagggaaagtgcaaagcacttcaagtgtg
gacagtcagtcatgtgtgatggtgcccccaagtgatgaagtggtgacaaatctggaaact
cttacaagcaaatgcctctatgggaagaactactgccggcagatcctctgcctgtatgaa
cttgccaaggagctgggctgttcctacacagatgttgctgcccagggcggcaaggcccta
ctccatgcaatcctggcctcccagcagcctgaccggtgcagacgtgcccaggccttcatc
agtacacagggcctccctccagacactgtggctgaacttgtggctgaagaagtgatgcag
gagctgctgacctcatctgagggaacaggacataagcaggtgttcagcccagcagaggaa
agccagacatttcttcagctgactgctctgtgtcaagaccacaccttggtaggaatgaag
ttactggataagatttcctctgttcctaatggacagctgtcttgcaccacagagctcctg
atcctggctcatcactgcttcaccctaacatgccatatggagggcatcatgcgagtcctg
caggccgcccggacgctcacagataaccacttggctcccaacgaggagtatgggctggtg
gtccggctcctcactggcattggaaggtacaatgagatgacgtacatatttgatttgctg
catcaaaaacactactttgaagtgctgatgaggaagaagctggatacgagtgggaccctg
aagacagccctgctggactacattaaacgctgccgccctggagacagtgagaagcacaac
atgattgccctgtgcttcagcatgtgccgagagatcggggagaaccatgaggcagctgcc
tatatccaactgaaactgatcgagtgtcaggcctgggaggacaacctcaaggatgggcag
cagctgaagcagctgctgttgaaggccctgaccttgatgctggatgcagccgagagttat
gccaaggactcctgtgtgcgacaggccctgcactgtcaccggctcaccaagttgataaca
ctacagattcactttctgaacactggccacaacacaatggtcatcaacttaggccgccaa
aagctgatggactgtatcacggccctgcctcggttttaccaggcatctattgtagccgag
gcctatgactttgttccagattgggccgaaattctgtaccaacaagtgattcttaaagga
gactttaattacttggaagaatttaagcaacaaaggttattaagacccagtatatttgaa
gagatttcaaaaaaatgtaaacatcagcctactgacacagtcacagaaaacctgaagaag
ttactctcgtactgtgaagatatctacttgcattacaagttggcgtatgaacacaaattt
tatgaaattgtaaatgtgcttctgaaggaccctcaaacaggctgctgtctgaaggacatg
cttgcaggctag
DBGET
integrated database retrieval system
