Heterocephalus glaber (naked mole-rat): 101702367
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Entry
101702367 CDS
T02812
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101702367
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hgl03032
]
101702367
03036 Chromosome and associated proteins [BR:
hgl03036
]
101702367
Enzymes [BR:
hgl01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
101702367
DNA replication proteins [BR:
hgl03032
]
Eukaryotic type
DNA Topoisomerases
101702367
Chromosome and associated proteins [BR:
hgl03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
101702367
Centrosome formation proteins
Centriole proteins
101702367
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
101702367
NCBI-ProteinID:
XP_012933042
LinkDB
All DBs
Position
Un
AA seq
1270 aa
AA seq
DB search
MTIYSQVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSI
ATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQT
KENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCSAVKHNRIKG
IPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDRYGVFPLRGKILNVREAS
HKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFI
HHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKWKVKYYKGLG
TSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKDWLTHFMEDRRQRKL
LGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRN
DKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGG
KDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMVLVNGAEGIG
TGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFRGTIEELAPNQYVINGEVAILN
STTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMTEEKL
AEAERAGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTALDILRDFFELRLKYYGLRKEWL
LGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKEAQQKV
PDEEDNEESDSEKETAKGDSAADTGPTFAYLLDMPLWYLTKEKKDELCKQRSEKEQELHT
LKKKSPSDLWKEDLAAFVEELEAVEAKEKQDEQVGLPGKGGKPKGKKAQMAEVLPSQQGT
RVIPRVTVEMKAEAEKKIKKKIKSENTEGTPAEDSVELESLKQRLEKKQKREPGARAKKQ
TTLPFKPIRKGKKRNPWSDSESDMSSTESNFDVPPREIEPRRAAAKTKFTMDLDSDEDFS
DSDEKAEEDDFVPSDASPPKAKTPPKFTKREPKPQKITVSVTGLEAAGAEDREPPADLPA
QPEATKPPPERSATMKKTTAKGQSSASTAGTKKRAAPKGAKKDPALNSEASAKPDPAKTK
YRRKRKPSTSDDSDSNFEKIISKGATSKKSKAESDDFQMALDSSVTPRAKSGRTKKPIKY
LEDSDDDDLF
NT seq
3813 nt
NT seq
+upstream
nt +downstream
nt
atgactatctacagccaggtaaaaggattccgtagttatgtggatatgtatttaaaggat
aagttagatgaaactggcaacccactgaaagtaatacatgaacaagtaaaccacagatgg
gaggtgtgtttaacaatgagtgaaaaagggttccagcaaattagcttcgtcaatagcatt
gctacttccaagggtggcagacatgttgactatgtagctgatcagattgtgaccaaactt
gttgatgtagtgaagaagaagaacaagggtggggttgcagtaaaagcacatcaggtgaaa
aatcacatgtggatttttgtgaatgccttaattgaaaacccaacctttgactctcagaca
aaagaaaacatgactttacaagccaagagctttggatcaacatgccaattaagtgaaaaa
ttcatcaaagctgcaattggctgtggtattgtagaaagcatactgaactgggtgaaattt
aaggcgcaagttcagttaaacaagaagtgttcagctgtaaaacataacagaatcaaggga
attcccaaacttgatgatgccaatgatgcaggaagccggaactccactgagtgtacactt
attctgactgagggggactcagccaaaactttggctgtttcaggccttggtgtggttggg
agagacagatatggggttttccctcttagaggaaaaatactcaatgtccgagaagcttct
cataaacagatcatggaaaatgctgaaattaataacatcatcaagattgtgggtcttcaa
tacaagaaaaactatgaagatgaagattctttgaagactcttcgttatgggaagataatg
attatgactgatcaggaccaagatggttcccatatcaaaggcttgttgattaattttatc
catcacaactggccctctcttctacgacatcgttttctggaggaattcatcactcccatt
gtaaaggtgtctaaaaataagcaggaaatggcattctacagccttcctgaatttgaagaa
tggaagagttctaccccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggc
accagcacatcaaaggaagctaaggagtacttcgcagatatgaaaagacatcgtatccaa
tttaaatattctgggcctgaggatgatgctgcgattagcctagcctttagcaaaaagcag
atagatgatcgaaaggattggttaactcatttcatggaagatagaagacaacggaagtta
cttggccttcctgaggattatttgtatgggcaaactaccacttacctgacatataatgac
ttcataaacaaggagcttatcctgttctcaaattctgacaatgagagatctatcccatct
atggtggatggtttgaaaccaggtcagagaaaagttttgtttacttgcttcaagcggaat
gacaagcgagaggtgaaggtcgcccagctggctgggtcagtggcggaaatgtcttcttac
catcacggtgagatgtcactaatgatgaccatcatcaatttggctcagaactttgtgggt
agcaataatctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggc
aaggattctgctagtcctcgatacatcttcaccatgctcagccctttggctcggttgtta
tttccaccaaaagatgatcatacattgaagttcttatacgatgacaaccaacgtgtggag
cctgaatggtacatccctatcatccccatggtgctggtgaatggtgctgaagggattggc
actgggtggtcctgcaaaatccccaactttgatgttcgcgaagttgtgaataacatcagg
cgtttaatggatggagaagaacctttgccaatgcttccaagttacaagaacttcagaggt
actattgaagagctggctccaaatcagtatgtgattaatggtgaagtagctattctgaat
tctacaaccattgaaatctcagagcttcccatcagaacatggacccagacgtataaagag
caggttctagaacccatgctgaatggcactgagaagacaccgcctctcataacagactat
agggaataccacacagataccactgtcaagtttgttgtgaagatgactgaagaaaaactg
gcagaggcagagcgagccggactgcacaaagtcttcaaactccaaacaagtctcacctgc
aactctatggtgctttttgaccatgtaggctgcttaaagaaatatgacacagcgttggac
atcctaagagacttctttgaactcaggctcaaatattatggattaagaaaagaatggctc
ctaggaatgcttggtgcagaatctgctaaactgaacaatcaagctcgctttatcttagag
aaaatagatggcaaaataatcattgaaaataaacctaagaaagaattaattaaagttctg
attcagaggggatatgattcagatcctgtgaaggcctggaaagaagcccagcaaaaggtt
ccagatgaagaagacaatgaagaaagtgacagcgagaaggagactgccaagggcgactcc
gccgcagataccgggccgaccttcgcctacctccttgacatgcccctctggtacctgacc
aaggaaaagaaagacgagttgtgcaagcagcgaagcgaaaaggagcaagagctgcacaca
ctgaagaaaaagagtccgtcagatctgtggaaagaagacttggctgcttttgttgaggaa
ctagaggctgttgaagccaaagaaaaacaagatgaacaagtaggacttcctgggaaagga
gggaaaccaaaagggaaaaaagcacagatggctgaagttttgccttctcaacaaggaaca
agggttattcctcgggtgacggtagagatgaaagcagaggcagaaaagaaaattaagaag
aaaatcaagagtgaaaatactgaaggaacccctgcggaggacagtgtggaactggaaagc
ctgaaacaaaggctagagaagaaacagaaaagagagccaggtgcccgggcaaagaaacaa
actaccttgccatttaaacctatcagaaaaggaaagaagagaaacccctggtctgattca
gaatcagatatgagtagtactgaaagtaattttgatgtcccgccacgagaaatagagcca
cggagagctgcagcaaaaaccaaatttacaatggatttggattcagatgaagatttctca
gattctgatgaaaaagctgaagaagacgattttgtcccatcagatgctagtcctcctaag
gccaaaactcccccaaaatttacaaaaagagaaccaaagccacagaaaatcaccgtgtca
gtaaccggcctggaggctgcaggtgctgaggacagggagccacctgctgacctcccagcc
cagcctgaggctacaaagccacctcctgagagaagcgcgaccatgaagaagaccacagca
aaaggtcagtcttctgcctccactgctggaaccaaaaagagggcagcaccaaaaggagcc
aaaaaagacccagccttgaattctgaggcctctgcaaagcccgatcccgccaaaaccaag
tatcgacgcaaaaggaagccatccacttcggatgattcggattctaactttgagaaaatc
atttctaaaggagccacaagcaagaaatccaaggccgagagcgatgacttccagatggcc
ctcgactcctccgtgactcctcgggcaaaatccgggcgcacaaagaagcctataaagtac
ctagaagactcagacgatgatgacctgttttaa
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