Heterocephalus glaber (naked mole-rat): 101702911 Help Entry 101702911         CDS       T02812                                  Symbol Rps6kb2 Name (RefSeq) ribosomal protein S6 kinase B2   KO K04688   ribosomal protein S6 kinase beta [EC:2.7.11.1] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl01522   Endocrine resistance hgl04012   ErbB signaling pathway hgl04066   HIF-1 signaling pathway hgl04140   Autophagy - animal hgl04150   mTOR signaling pathway hgl04151   PI3K-Akt signaling pathway hgl04152   AMPK signaling pathway hgl04211   Longevity regulating pathway hgl04213   Longevity regulating pathway - multiple species hgl04350   TGF-beta signaling pathway hgl04371   Apelin signaling pathway hgl04666   Fc gamma R-mediated phagocytosis hgl04714   Thermogenesis hgl04910   Insulin signaling pathway hgl04931   Insulin resistance hgl05163   Human cytomegalovirus infection hgl05165   Human papillomavirus infection hgl05170   Human immunodeficiency virus 1 infection hgl05200   Pathways in cancer hgl05205   Proteoglycans in cancer hgl05207   Chemical carcinogenesis - receptor activation hgl05210   Colorectal cancer hgl05212   Pancreatic cancer hgl05221   Acute myeloid leukemia hgl05224   Breast cancer hgl05225   Hepatocellular carcinoma hgl05226   Gastric cancer hgl05231   Choline metabolism in cancer hgl05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     101702911 (Rps6kb2)    04350 TGF-beta signaling pathway     101702911 (Rps6kb2)    04371 Apelin signaling pathway     101702911 (Rps6kb2)    04066 HIF-1 signaling pathway     101702911 (Rps6kb2)    04151 PI3K-Akt signaling pathway     101702911 (Rps6kb2)    04152 AMPK signaling pathway     101702911 (Rps6kb2)    04150 mTOR signaling pathway     101702911 (Rps6kb2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101702911 (Rps6kb2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     101702911 (Rps6kb2)   09152 Endocrine system    04910 Insulin signaling pathway     101702911 (Rps6kb2)   09149 Aging    04211 Longevity regulating pathway     101702911 (Rps6kb2)    04213 Longevity regulating pathway - multiple species     101702911 (Rps6kb2)   09159 Environmental adaptation    04714 Thermogenesis     101702911 (Rps6kb2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101702911 (Rps6kb2)    05205 Proteoglycans in cancer     101702911 (Rps6kb2)    05207 Chemical carcinogenesis - receptor activation     101702911 (Rps6kb2)    05231 Choline metabolism in cancer     101702911 (Rps6kb2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101702911 (Rps6kb2)   09162 Cancer: specific types    05210 Colorectal cancer     101702911 (Rps6kb2)    05212 Pancreatic cancer     101702911 (Rps6kb2)    05225 Hepatocellular carcinoma     101702911 (Rps6kb2)    05226 Gastric cancer     101702911 (Rps6kb2)    05221 Acute myeloid leukemia     101702911 (Rps6kb2)    05224 Breast cancer     101702911 (Rps6kb2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101702911 (Rps6kb2)    05163 Human cytomegalovirus infection     101702911 (Rps6kb2)    05165 Human papillomavirus infection     101702911 (Rps6kb2)   09167 Endocrine and metabolic disease    04931 Insulin resistance     101702911 (Rps6kb2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101702911 (Rps6kb2)    01522 Endocrine resistance     101702911 (Rps6kb2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hgl01001]     101702911 (Rps6kb2) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      101702911 (Rps6kb2) Protein kinases [BR:hgl01001]  Serine/threonine kinases: AGC group   RSK family [OT]    101702911 (Rps6kb2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal FTA2 ABC1 Seadorna_VP7 Motif Other DBs NCBI-GeneID:  101702911 NCBI-ProteinID:  XP_004852295 UniProt:  A0AAX6PHA8 LinkDB All DBs Position Un AA seq 478 aa AA seqDB search MAAVFDLDLETEEGSEGEPEFSPAEVCPLAELRAAGLEPVGHYEEVELTENSVNPRLERI GPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIICNAKDTAHTQAERNI LESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLAL GHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILV RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLVKK FLKRNPSQRIGGGPGDAADVQRHPFFRHFNWDDLLARRVDPPFRPSLQSEEDVSQFDTHF TRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRTPI SPLKFSPFEGLRPSPGPPEPMEPPLPPPPPLPSSTAPLPIRPPSGTKKSKKGRGHPGH NT seq 1437 nt NT seq  +upstreamnt  +downstreamnt atggcagccgtgtttgatctggacttggagacagaagaaggcagcgagggcgagccagag ttcagcccagcggaggtgtgtcctcttgccgagttgagggctgctggcctggagcctgtg ggacactatgaggaggtggagctgactgagaacagcgtgaacccacgcctggagcgcatc gggccccactgctttgaattgctgagagtactgggcaaagggggctatgggaaggtgttc caggtgcgaaaggtgcaaggcactaacttggggaaaatatatgccatgaaagtcctgagg aaggccaaaatcatttgtaatgccaaggacacagcacatacccaggctgaacggaacatt ctagagtcagtgaagcatcccttcattgtagaactggcctatgccttccagacaggtggc aaactctacctcatcctggagtgcctcagtggtggtgagctcttcacacatctggagcga gaaggcatcttcctggaagacacagcctgcttctacctagctgagatcaccctggctctg ggccatctccattcccaaggcatcatttaccgagacctcaagcctgagaacatcatgctc aacagccagggccacatcaaactgacagactttggactgtgcaaggaatccattcatgag ggcgctgtcactcacaccttctgtggcaccattgagtacatggcccccgagattctggtg cgcagtggccacaaccgagcagtggactggtggagcctgggggccctgatgtatgacatg ctcactggatcgccacccttcactgcagagaacaggaagaagaccatggacaagatcatc aaggggaagctggtgctgcccccctacctcaccccagatgcccgggaccttgtcaaaaag tttctgaagcggaatcccagccaacggattgggggtggcccaggggatgctgctgatgtg cagaggcaccccttcttccggcacttcaattgggatgatctcctggcccgccgtgtggac ccccctttcaggccgagtctgcagtcagaggaggatgtgagtcagtttgacacccacttc acacggcagacaccggtggacagcccagatgacacggccctcagtgagagtgccaatcag gccttcctgggcttcacatatgtggccccttccgtcctggacagcatcaaagagggcttc tccttccagcccaagttgcgctccccacgtcgcctcaacagcagcccccggaccccaatc agccccctcaagttctctccctttgagggattgcgacccagcccaggcccaccagaaccc atggaaccacctctgccaccaccaccaccactgccctcaagcactgctcccctccccatc cgtcccccctcagggaccaagaagtccaagaagggccgtgggcaccctgggcactag

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