KEGG   Heterocephalus glaber (naked mole-rat): 101703043
Entry
101703043         CDS       T02812                                 
Symbol
Gnai3
Name
(RefSeq) G protein subunit alpha i3
  KO
K04630  guanine nucleotide-binding protein G(i) subunit alpha
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04015  Rap1 signaling pathway
hgl04022  cGMP-PKG signaling pathway
hgl04024  cAMP signaling pathway
hgl04062  Chemokine signaling pathway
hgl04071  Sphingolipid signaling pathway
hgl04081  Hormone signaling
hgl04082  Neuroactive ligand signaling
hgl04261  Adrenergic signaling in cardiomyocytes
hgl04360  Axon guidance
hgl04371  Apelin signaling pathway
hgl04540  Gap junction
hgl04611  Platelet activation
hgl04670  Leukocyte transendothelial migration
hgl04713  Circadian entrainment
hgl04723  Retrograde endocannabinoid signaling
hgl04724  Glutamatergic synapse
hgl04725  Cholinergic synapse
hgl04726  Serotonergic synapse
hgl04727  GABAergic synapse
hgl04728  Dopaminergic synapse
hgl04730  Long-term depression
hgl04914  Progesterone-mediated oocyte maturation
hgl04915  Estrogen signaling pathway
hgl04916  Melanogenesis
hgl04921  Oxytocin signaling pathway
hgl04923  Regulation of lipolysis in adipocytes
hgl04924  Renin secretion
hgl04926  Relaxin signaling pathway
hgl04928  Parathyroid hormone synthesis, secretion and action
hgl04934  Cushing syndrome
hgl04935  Growth hormone synthesis, secretion and action
hgl04971  Gastric acid secretion
hgl05012  Parkinson disease
hgl05030  Cocaine addiction
hgl05032  Morphine addiction
hgl05034  Alcoholism
hgl05133  Pertussis
hgl05142  Chagas disease
hgl05145  Toxoplasmosis
hgl05163  Human cytomegalovirus infection
hgl05170  Human immunodeficiency virus 1 infection
hgl05200  Pathways in cancer
hgl05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101703043 (Gnai3)
   04371 Apelin signaling pathway
    101703043 (Gnai3)
   04071 Sphingolipid signaling pathway
    101703043 (Gnai3)
   04024 cAMP signaling pathway
    101703043 (Gnai3)
   04022 cGMP-PKG signaling pathway
    101703043 (Gnai3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    101703043 (Gnai3)
   04081 Hormone signaling
    101703043 (Gnai3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101703043 (Gnai3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101703043 (Gnai3)
   04670 Leukocyte transendothelial migration
    101703043 (Gnai3)
   04062 Chemokine signaling pathway
    101703043 (Gnai3)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    101703043 (Gnai3)
   04915 Estrogen signaling pathway
    101703043 (Gnai3)
   04914 Progesterone-mediated oocyte maturation
    101703043 (Gnai3)
   04921 Oxytocin signaling pathway
    101703043 (Gnai3)
   04926 Relaxin signaling pathway
    101703043 (Gnai3)
   04935 Growth hormone synthesis, secretion and action
    101703043 (Gnai3)
   04928 Parathyroid hormone synthesis, secretion and action
    101703043 (Gnai3)
   04916 Melanogenesis
    101703043 (Gnai3)
   04924 Renin secretion
    101703043 (Gnai3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101703043 (Gnai3)
  09154 Digestive system
   04971 Gastric acid secretion
    101703043 (Gnai3)
  09156 Nervous system
   04724 Glutamatergic synapse
    101703043 (Gnai3)
   04727 GABAergic synapse
    101703043 (Gnai3)
   04725 Cholinergic synapse
    101703043 (Gnai3)
   04728 Dopaminergic synapse
    101703043 (Gnai3)
   04726 Serotonergic synapse
    101703043 (Gnai3)
   04730 Long-term depression
    101703043 (Gnai3)
   04723 Retrograde endocannabinoid signaling
    101703043 (Gnai3)
  09158 Development and regeneration
   04360 Axon guidance
    101703043 (Gnai3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101703043 (Gnai3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101703043 (Gnai3)
   05207 Chemical carcinogenesis - receptor activation
    101703043 (Gnai3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101703043 (Gnai3)
   05163 Human cytomegalovirus infection
    101703043 (Gnai3)
  09171 Infectious disease: bacterial
   05133 Pertussis
    101703043 (Gnai3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101703043 (Gnai3)
   05142 Chagas disease
    101703043 (Gnai3)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    101703043 (Gnai3)
  09165 Substance dependence
   05030 Cocaine addiction
    101703043 (Gnai3)
   05032 Morphine addiction
    101703043 (Gnai3)
   05034 Alcoholism
    101703043 (Gnai3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101703043 (Gnai3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hgl04147]
    101703043 (Gnai3)
   04031 GTP-binding proteins [BR:hgl04031]
    101703043 (Gnai3)
Exosome [BR:hgl04147]
 Exosomal proteins
  Proteins found in most exosomes
   101703043 (Gnai3)
GTP-binding proteins [BR:hgl04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 1 (Gi/o) [OT]
    101703043 (Gnai3)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA Roc TniB FtsK_SpoIIIE AAA_29
Other DBs
NCBI-GeneID: 101703043
NCBI-ProteinID: XP_004853697
UniProt: A0AAX6PL95
LinkDB
Position
Un
AA seq 354 aa
MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG
YSEEECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGIMT
SELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQTSYIPTQQDVLRTRVK
TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA
AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY
NT seq 1065 nt   +upstreamnt  +downstreamnt
atgggctgcacactgagcgccgaagacaaggcggcggtggagcggagtaagatgatcgac
cgcaatttgcgggaggacggggagaaagctgccaaagaagtgaagctgctgttactcggt
gctggagaatctggtaaaagtaccattgtgaaacagatgaaaatcattcatgaagacggc
tattcagaagaagaatgtaaacaatataaagtagttgtctacagcaatactatacagtcc
atcattgcaatcataagagccatgggacggctaaagattgattttggggaagctgccaga
gcagatgatgctcggcagttatttgttttagctggcagtgctgaagaaggaatcatgact
tcagaactcgcaggagtgattaaacggttatggcgagatggtggggtccaggcatgcttt
agcagatccagggaatatcagctcaatgattctgcctcatattacctaaatgatttggat
agaatatcacaaaccagctacattccaactcagcaagatgttcttcggacaagagtgaag
accacaggcattgtggaaacacatttcaccttcaaagacctatacttcaagatgtttgat
gttggtggccaaagatcagaacgaaaaaaatggattcactgttttgagggagtgacagca
attatcttctgtgtggccctcagtgattatgaccttgttttagctgaggatgaggagatg
aaccgaatgcatgaaagcatgaaactgttcgacagcatttgtaacaacaaatggtttaca
gacacttcaatcattctcttccttaacaagaaagacctttttgaagaaaaaataaagagg
agtccattaactatctgttatccagaatatacaggttctaatacatatgaagaggcagct
gcttacattcagtgccagtttgaagatttgaacagaaggaaagataccaaggagatctat
actcacttcacctgtgccacagacaccaagaatgtgcagtttgtttttgatgctgttaca
gatgtcatcattaaaaacaacttaaaggaatgtggactttattga

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