Heterocephalus glaber (naked mole-rat): 101703711 Help Entry 101703711         CDS       T02812                                  Symbol Lrp6 Name (RefSeq) LDL receptor related protein 6   KO K03068   low density lipoprotein receptor-related protein 5/6 Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl04150   mTOR signaling pathway hgl04310   Wnt signaling pathway hgl04928   Parathyroid hormone synthesis, secretion and action hgl05010   Alzheimer disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05200   Pathways in cancer hgl05224   Breast cancer hgl05225   Hepatocellular carcinoma hgl05226   Gastric cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     101703711 (Lrp6)    04150 mTOR signaling pathway     101703711 (Lrp6)  09150 Organismal Systems   09152 Endocrine system    04928 Parathyroid hormone synthesis, secretion and action     101703711 (Lrp6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101703711 (Lrp6)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     101703711 (Lrp6)    05226 Gastric cancer     101703711 (Lrp6)    05224 Breast cancer     101703711 (Lrp6)   09164 Neurodegenerative disease    05010 Alzheimer disease     101703711 (Lrp6)    05022 Pathways of neurodegeneration - multiple diseases     101703711 (Lrp6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hgl04131]     101703711 (Lrp6) Membrane trafficking [BR:hgl04131]  Endocytosis   Clathrin-mediated endocytosis    Low-density lipoprotein receptor (LDLR) family proteins     101703711 (Lrp6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ldl_recept_b FXa_inhibition Ldl_recept_a DUF5050 SGL cEGF EGF Motif Other DBs NCBI-GeneID:  101703711 NCBI-ProteinID:  XP_004845929 UniProt:  A0A0P6JF39 LinkDB All DBs Position Un AA seq 1613 aa AA seqDB search MGPVLRSLLACSLCVLLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVF GHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIE VSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFVIINTE IYWPNGLTLDYEERKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWT DWNTHSILACSKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMS PVKPFYQCACPTGVKLLENGKTCKNGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIR HAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWT DTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGEIPKIERAALDGSD RVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTL LGNYVYWTDWQRRSIERVHKRSAEREIIIDQLPDLMGLKATNVHRIIGSNPCAEENGGCS HLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETNNNNVAIPLTG VKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLY WADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDG SERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQ YQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHC SHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILP IHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSVPNQNLEIQPYDLS IDIYSRYIYWTCEATNVINVTRLDGRSIGVVLKGDQDRPRAIVVNPEKGYMYFTNLQERS PKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLE DSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQ EYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTGE IDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEK NCEVLCLIDQFRCASGQCIGKHKKCDHNVDCSDKSDELDCYPTEEPAPQATNTVGSVIGV IVTIFVSGTIYFICQRMLCPRMKGDGETMANDYVVHGPASVPLGYVPHPSSLSGSLPGMS RGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTM EFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRVTSVATAKGYTSDL NYDSEPVPPPPTPRSQYLSAEENYESCPPSPYTERSYSHHLYPPPPSPCTDSS NT seq 4842 nt NT seq  +upstreamnt  +downstreamnt atggggcccgtcctgaggagcctcctggcctgcagtctctgcgtgctcttgagagcggcc cctttgttgctttatgcaaacagacgggacttgcggttggtggatgctacaaatggcaaa gagaatgctacaatagtagttggaggattggaggacgcagctgcagtggactttgtgttt ggtcatggcttgatctactggagtgacgtcagcgaagaagctattaagcgaacagaattt aataaaactgagagtgttcagaatgttgttgtttctggattattgtcccctgatggactg gcatgcgattggcttggagaaaaattatactggacagattcagaaactaatcggattgaa gtttctaatttagatggatctctacgaaaagttttgttttggcaagagttggatcaaccc agagctattgccttagatccttcaagtgggttcatgtactggactgactggggagaagtg ccaaagatagaacgtgctggaatggatggttcaagtcgttttgttataataaatactgaa atttactggccaaatggactgactttggattatgaggaacgaaagctttattgggcagat gccaaacttaatttcatccacaaatcaaacctggatggaacaaatagacaggcagtggtt aaaggttcccttccacatccttttgcattaacgttatttgaggacacattgtactggact gactggaatacacactccattttggcttgcagcaagtacactggcgagggtctgcgtgaa atccattctaacatcttctctcccatggatatacatgccttcagccagcagaggcagcca aatgctacaaatccatgtggaattgataatggtggttgttctcatttgtgtttgatgtct ccagtcaagccattttatcagtgtgcttgcccaacaggggtcaaacttctggagaatgga aaaacctgcaaaaatggtgccactgaattactgcttttagcccgaaggacagacttgaga cgcatttctttggatacaccagattttacagacatcgttctgcaattagaagacattcgt catgccattgccatagattatgatcctgtggaaggctatatctactggactgacgatgaa gtgagggccatacgccgctccttcatagatggatctggcagtcagtttgtggtcactgct caaattgcccatcctgatggtattgctgttgactgggttgcacgaaatctttactggaca gacactggcactgatcggatagaagtgacaaggctcaatgggaccatgagaaagatcttg atttcagaagacttagaggaaccccgggctattgtgttagatcccatggttgggtacatg tattggactgactggggagaaatcccgaaaattgaacgagcagctctagatggctctgac cgagtagtattggttaatacttctcttggttggccgaatggtttagctttggattatgat gaaggcaaaatatactggggggatgccaaaacggacaaaattgaggttatgaatactgat ggcactggaagacgagtactagtggaagacaaaatccctcacatatttgggtttactttg ttgggtaactatgtttactggactgactggcagaggcgcagcatcgaaagagtgcataag cgaagtgcagagagggaaatcatcatagatcagctgcctgacctcatggggctaaaggcc acaaatgttcatcgaatcattggttccaacccttgtgctgaggagaatgggggttgtagt catctttgcctctatagacctcagggccttcgctgtgcctgccccattggctttgaactc attagtgacatgaagacctgcattgtccctgaggctttccttttgttttcacggagagca gatataagacgaatttctttggaaacaaacaataataatgtggccattccactgactggt gtcaaagaagcttctgctttggattttgatgtgacagacaatcgaatttattggactgat atatcactcaagaccatcagcagagccttcatgaatggcagcgcgctggaacatgtggta gaatttggcttggattacccagaaggcatggcagtggactggcttgggaagaacttatac tgggctgacaccggaacaaatcgaatcgaagtgtcaaagttggatggacagcaccgacaa gttttggtttggaaagatctggacagccccagagctctagctttggaccccgctgaagga tttatgtattggactgaatggggtggaaaacccaagatagacagagcagctatggatgga agtgagcgtactacactggttccaaatgtagggcgggcaaatggcctgactattgattat gctaaaaggaggctttattggacagacttggacaccaacttaatagaatcctcaaatatg cttggactcaaccgtgaagttatagcagatgacctgccccatccttttggcttaactcaa taccaagattacatctactggactgactggagccgacgcagcattgagcgagccaacaaa accagcggccagaaccgcaccatcattcagggccatttggactacgtgatggacatcctt gtcttccactcctcacggcaggcagggtggaacgagtgtgcttccagcaacgggcactgc tcccacctctgcctggcagtgccggttggaggttttgtttgtggatgccctgcccactac tcactgaatgctgacaacaggacttgtagtgctcctaccactttcctgctcttcagtcag aagagtgccatcaaccgcatggtgattgatgaacagcagagtcctgacatcattcttcct atccatagccttcggaatgtccgggccattgattatgacccactggacaaacaactctat tggatcgactcacgacaaaacatgatccgaaaggcacaggaggatggcagccagggcttt actgtggtggtgagctcagttccaaaccaaaacctagaaatacagccctatgatctcagc attgacatttatagccgctatatctactggacttgtgaggctacaaatgtcattaatgtg acaagattagacgggagatcgattggcgtggttctaaaaggcgatcaagaccgaccccga gccattgtggttaatccagagaaggggtatatgtattttaccaatcttcaggaaaggtct cccaaaatagaacgggctgctttagatggaacagaacgtgaggtcctgtttttcagtggc ttaagtaaaccaattgctttagctcttgatagcaggttgggcaaactcttttgggctgat tcagatctccggcgaattgaaagcagtgatctctcaggtgccaacaggatagtgttagaa gactccaatatcttgcagcctgtgggactgactgtgtttgaaaactggctctactggatt gataagcagcaacaaatgattgaaaaaatagacatgacaggtcgagagggcagaactaaa gtccaggctcggattgcccagcttagtgacattcatgcagtaaaggagctgaatcttcag gagtacagacagcacccttgtgctcaggataatggtggttgttcacacatttgtcttgta aaaggcgatggtactacaaggtgttcttgtcccatgcacctggttctgcttcaagatgag ctttcatgtggagagcccccaacatgttctcctcagcagtttacttgtttcactggggaa attgactgtatccctgtggcttggcgttgtgatgggtttactgaatgtgaagaccacagt gatgaactcaattgtcctgtgtgctcagagtcccagttccagtgtgccagtgggcagtgt attgatggtgccctccgatgcaatggggatgcaaactgccaggataaatcagatgaaaag aactgtgaagtgctttgtttaattgatcagttccgctgtgccagtggccagtgcattgga aagcacaagaaatgtgatcataatgtggattgcagtgacaaatctgatgaactggattgt tatccaactgaagagccagcaccacaggccaccaataccgttgggtcagtaattggagta attgtcaccatttttgtgtctggaaccatatactttatctgccagaggatgttgtgtcca cgcatgaagggagatggggaaactatggccaacgactatgtggttcatggaccagcgtct gtgcctctgggttatgtgccacacccgagctctctgtcagggtctcttccaggaatgtct cgaggtaaatcaatgatcagttccctcagtatcatggggggaagcagtggacccccttat gatcgagcacatgtcacaggcgcgtcgtcaagcagttcttcaagtaccaaaggcacttac ttccctgcaattttgaacccaccaccatcccctgccacagagcgatcacattacactatg gaatttggttattcttcaaacagtccttccactcataggtcatacagttacaggccctac agctaccggcactttgcaccccctaccacaccctgcagcacagatgtttgtgacagtgac tatgctcctagccggagagtgacctcggtggcaacagccaaaggctacaccagtgacttg aactatgactcagagcctgtgcccccacctcccacgccccgaagccagtacttgtcggca gaggagaactatgaaagctgccccccttctccatacacagagaggagctattcccatcac ctctacccaccgccaccctcgccctgcacagactcctcctga

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