Heterocephalus glaber (naked mole-rat): 101703827
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Entry
101703827 CDS
T02812
Symbol
Src
Name
(RefSeq) SRC proto-oncogene, non-receptor tyrosine kinase
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl01521
EGFR tyrosine kinase inhibitor resistance
hgl01522
Endocrine resistance
hgl04012
ErbB signaling pathway
hgl04015
Rap1 signaling pathway
hgl04062
Chemokine signaling pathway
hgl04081
Hormone signaling
hgl04137
Mitophagy - animal
hgl04144
Endocytosis
hgl04360
Axon guidance
hgl04370
VEGF signaling pathway
hgl04510
Focal adhesion
hgl04517
IgSF CAM signaling
hgl04520
Adherens junction
hgl04530
Tight junction
hgl04540
Gap junction
hgl04611
Platelet activation
hgl04613
Neutrophil extracellular trap formation
hgl04625
C-type lectin receptor signaling pathway
hgl04727
GABAergic synapse
hgl04750
Inflammatory mediator regulation of TRP channels
hgl04810
Regulation of actin cytoskeleton
hgl04912
GnRH signaling pathway
hgl04915
Estrogen signaling pathway
hgl04917
Prolactin signaling pathway
hgl04919
Thyroid hormone signaling pathway
hgl04921
Oxytocin signaling pathway
hgl04926
Relaxin signaling pathway
hgl05100
Bacterial invasion of epithelial cells
hgl05135
Yersinia infection
hgl05152
Tuberculosis
hgl05161
Hepatitis B
hgl05163
Human cytomegalovirus infection
hgl05167
Kaposi sarcoma-associated herpesvirus infection
hgl05168
Herpes simplex virus 1 infection
hgl05203
Viral carcinogenesis
hgl05205
Proteoglycans in cancer
hgl05207
Chemical carcinogenesis - receptor activation
hgl05208
Chemical carcinogenesis - reactive oxygen species
hgl05219
Bladder cancer
hgl05417
Lipid and atherosclerosis
hgl05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101703827 (Src)
04015 Rap1 signaling pathway
101703827 (Src)
04370 VEGF signaling pathway
101703827 (Src)
09133 Signaling molecules and interaction
04081 Hormone signaling
101703827 (Src)
04517 IgSF CAM signaling
101703827 (Src)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101703827 (Src)
04137 Mitophagy - animal
101703827 (Src)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101703827 (Src)
04520 Adherens junction
101703827 (Src)
04530 Tight junction
101703827 (Src)
04540 Gap junction
101703827 (Src)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101703827 (Src)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101703827 (Src)
04613 Neutrophil extracellular trap formation
101703827 (Src)
04625 C-type lectin receptor signaling pathway
101703827 (Src)
04062 Chemokine signaling pathway
101703827 (Src)
09152 Endocrine system
04912 GnRH signaling pathway
101703827 (Src)
04915 Estrogen signaling pathway
101703827 (Src)
04917 Prolactin signaling pathway
101703827 (Src)
04921 Oxytocin signaling pathway
101703827 (Src)
04926 Relaxin signaling pathway
101703827 (Src)
04919 Thyroid hormone signaling pathway
101703827 (Src)
09156 Nervous system
04727 GABAergic synapse
101703827 (Src)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101703827 (Src)
09158 Development and regeneration
04360 Axon guidance
101703827 (Src)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101703827 (Src)
05207 Chemical carcinogenesis - receptor activation
101703827 (Src)
05208 Chemical carcinogenesis - reactive oxygen species
101703827 (Src)
05203 Viral carcinogenesis
101703827 (Src)
09162 Cancer: specific types
05219 Bladder cancer
101703827 (Src)
09172 Infectious disease: viral
05161 Hepatitis B
101703827 (Src)
05168 Herpes simplex virus 1 infection
101703827 (Src)
05163 Human cytomegalovirus infection
101703827 (Src)
05167 Kaposi sarcoma-associated herpesvirus infection
101703827 (Src)
09171 Infectious disease: bacterial
05135 Yersinia infection
101703827 (Src)
05152 Tuberculosis
101703827 (Src)
05100 Bacterial invasion of epithelial cells
101703827 (Src)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101703827 (Src)
05418 Fluid shear stress and atherosclerosis
101703827 (Src)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101703827 (Src)
01522 Endocrine resistance
101703827 (Src)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101703827 (Src)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hgl04131
]
101703827 (Src)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101703827 (Src)
Protein kinases [BR:
hgl01001
]
Non-receptor tyrosine kinases
SRC family
101703827 (Src)
Membrane trafficking [BR:
hgl04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
101703827 (Src)
Endocytosis
Clathrin-mediated endocytosis
Kinases
101703827 (Src)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
101703827 (Src)
Macropinocytosis
Kinases
101703827 (Src)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
ABC1
SH2_1
Haspin_kinase
DUF7063
Motif
Other DBs
NCBI-GeneID:
101703827
NCBI-ProteinID:
XP_004867856
UniProt:
A0AAX6Q970
LinkDB
All DBs
Position
Un
AA seq
553 aa
AA seq
DB search
MGSNKSKPKDAGPRRRSLEPAESVHGPGGGAFPASQTPSKPASADGHRGPAAAFAPAAAE
SKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNTENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVVYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggatgccggccctcggcggcgcagcctggagccc
gccgagagcgtgcacggcccgggcggcggcgccttccccgcctcgcagacccccagcaag
ccggcctcggccgacggccaccgcgggcccgcggccgccttcgcccccgccgccgccgag
tccaagctcttcgggggcttcaactcttcggacaccgtcacctccccgcagcgcgcgggg
ccgctggccggtggagtgaccacctttgtggccctctatgactacgagtcccggacggag
actgatctttccttcaagaaaggggagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcacactcgctcagcacaggacagacgggctatatccccagcaactatgtggcaccctcg
gactccatccaggctgaggagtggtactttggcaagatcaccaggcgggagtcagagcgg
ttgctgcttaacacggagaacccgagaggcaccttcctggtgcgagaaagtgaaactacg
aaaggtgcctactgcctctctgtgtctgactttgacaacgccaagggcctcaatgtgaag
cactacaagatccgcaagctggacagcggtggcttctacatcacctcacgcacccagttc
aacagcctgcagcagctcgttgtctattactccaaacacgctgatggcctgtgccaccgc
ctcaccaccgtgtgccccacgtccaagccacagacccagggcctggccaaggatgcctgg
gagatcccccgggaatccctgcggctggaggtcaagctgggccagggctgctttggggag
gtgtggatgggaacctggaacggcaccaccagggtggccatcaagaccctgaagccgggc
accatgtctccggaggccttcctgcaggaggcccaggtcatgaagaaactgaggcacgag
aagctggtgcagctgtacgccgtggtgtccgaggagcccatctacatcgtcacagagtac
atgagcaaggggagtttgctggactttctcaagggggaaacgggcaagtacctgcggctg
cctcaactggtggacatggccgctcagattgcctcaggcatggcgtatgtggagcggatg
aactacgtccaccgggacctgcgtgccgccaacatcctagttggggagaacctggtgtgc
aaagtggctgacttcgggctggcccggcttattgaagacaatgagtacacagcccggcaa
ggtgccaagttccccatcaagtggacggccccagaagccgccctctatggccgcttcacc
atcaagtcagatgtatggtcctttgggatcctgctgaccgagctcacaacaaagggcagg
gtgccctaccctgggatggtgaaccgtgaggtgctggaccaggtggagcggggctaccgc
atgccctgcccacctgagtgccccgagtccctgcatgacctcatgtgccagtgctggcgg
aaggagcccgaggagcggcccaccttcgagtacctgcaggccttcctggaggactacttc
acgtccaccgagccccagtaccagcctggggagaacctatag
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