KEGG   Heterocephalus glaber (naked mole-rat): 101704157
Entry
101704157         CDS       T02812                                 
Symbol
Socs3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04120  Ubiquitin mediated proteolysis
hgl04380  Osteoclast differentiation
hgl04630  JAK-STAT signaling pathway
hgl04668  TNF signaling pathway
hgl04910  Insulin signaling pathway
hgl04917  Prolactin signaling pathway
hgl04920  Adipocytokine signaling pathway
hgl04930  Type II diabetes mellitus
hgl04931  Insulin resistance
hgl04932  Non-alcoholic fatty liver disease
hgl04935  Growth hormone synthesis, secretion and action
hgl05160  Hepatitis C
hgl05164  Influenza A
hgl05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101704157 (Socs3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    101704157 (Socs3)
   04668 TNF signaling pathway
    101704157 (Socs3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    101704157 (Socs3)
   04920 Adipocytokine signaling pathway
    101704157 (Socs3)
   04917 Prolactin signaling pathway
    101704157 (Socs3)
   04935 Growth hormone synthesis, secretion and action
    101704157 (Socs3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101704157 (Socs3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    101704157 (Socs3)
   05164 Influenza A
    101704157 (Socs3)
   05168 Herpes simplex virus 1 infection
    101704157 (Socs3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101704157 (Socs3)
   04932 Non-alcoholic fatty liver disease
    101704157 (Socs3)
   04931 Insulin resistance
    101704157 (Socs3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hgl04121]
    101704157 (Socs3)
Ubiquitin system [BR:hgl04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     101704157 (Socs3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 101704157
NCBI-ProteinID: XP_004860883
UniProt: G5AVF0
LinkDB
Position
Un
AA seq 226 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGASSSPPSEPSSPSEEPEQQPPAQPPPGSPPRKAYYIYSGGEKIPLVLS
RPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 681 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ttgcaggagagcggtttctactggagcgccgtgaccggcggcgaggcaaacctgctgctc
agcgccgagccggccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc
acgctgagcgtcaagacccagtccgggacgaagaaccttcgcatccaatgcgagggtggc
agcttctcgctccagagcgacccgcggagcacgcagcccgtgccccgcttcgactgcgtg
ctcaaactggtgcaccactacatgccgccccccggcgcctcctcctcgcccccttccgaa
ccctcctcgccctccgaggagcctgaacagcagccgcctgcccagccgcctccagggagc
cctcccaggaaagcctattacatctactcggggggcgagaagatccccctggtgttgagc
cggcccctctcctccaacgtggccacccttcagcatctctgtcggaagactgtcaatggg
cacctggactcttacgagaaagtcacccagctgccggggcccatccgggagttcctggac
cagtacgatgcgcccctttaa

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