Heterocephalus glaber (naked mole-rat): 101704309 Help Entry 101704309         CDS       T02812                                  Symbol Il1b Name (RefSeq) interleukin 1 beta   KO K04519   interleukin 1 beta Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl01523   Antifolate resistance hgl04010   MAPK signaling pathway hgl04060   Cytokine-cytokine receptor interaction hgl04064   NF-kappa B signaling pathway hgl04217   Necroptosis hgl04380   Osteoclast differentiation hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04623   Cytosolic DNA-sensing pathway hgl04625   C-type lectin receptor signaling pathway hgl04640   Hematopoietic cell lineage hgl04657   IL-17 signaling pathway hgl04659   Th17 cell differentiation hgl04668   TNF signaling pathway hgl04750   Inflammatory mediator regulation of TRP channels hgl04932   Non-alcoholic fatty liver disease hgl04933   AGE-RAGE signaling pathway in diabetic complications hgl04936   Alcoholic liver disease hgl04940   Type I diabetes mellitus hgl05010   Alzheimer disease hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05132   Salmonella infection hgl05133   Pertussis hgl05134   Legionellosis hgl05135   Yersinia infection hgl05140   Leishmaniasis hgl05142   Chagas disease hgl05143   African trypanosomiasis hgl05144   Malaria hgl05146   Amoebiasis hgl05152   Tuberculosis hgl05162   Measles hgl05163   Human cytomegalovirus infection hgl05164   Influenza A hgl05168   Herpes simplex virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05321   Inflammatory bowel disease hgl05323   Rheumatoid arthritis hgl05332   Graft-versus-host disease hgl05417   Lipid and atherosclerosis hgl05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101704309 (Il1b)    04064 NF-kappa B signaling pathway     101704309 (Il1b)    04668 TNF signaling pathway     101704309 (Il1b)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101704309 (Il1b)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101704309 (Il1b)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101704309 (Il1b)    04620 Toll-like receptor signaling pathway     101704309 (Il1b)    04621 NOD-like receptor signaling pathway     101704309 (Il1b)    04623 Cytosolic DNA-sensing pathway     101704309 (Il1b)    04625 C-type lectin receptor signaling pathway     101704309 (Il1b)    04659 Th17 cell differentiation     101704309 (Il1b)    04657 IL-17 signaling pathway     101704309 (Il1b)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101704309 (Il1b)   09158 Development and regeneration    04380 Osteoclast differentiation     101704309 (Il1b)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     101704309 (Il1b)    05164 Influenza A     101704309 (Il1b)    05162 Measles     101704309 (Il1b)    05168 Herpes simplex virus 1 infection     101704309 (Il1b)    05163 Human cytomegalovirus infection     101704309 (Il1b)   09171 Infectious disease: bacterial    05132 Salmonella infection     101704309 (Il1b)    05135 Yersinia infection     101704309 (Il1b)    05133 Pertussis     101704309 (Il1b)    05134 Legionellosis     101704309 (Il1b)    05152 Tuberculosis     101704309 (Il1b)   09174 Infectious disease: parasitic    05146 Amoebiasis     101704309 (Il1b)    05144 Malaria     101704309 (Il1b)    05140 Leishmaniasis     101704309 (Il1b)    05142 Chagas disease     101704309 (Il1b)    05143 African trypanosomiasis     101704309 (Il1b)   09163 Immune disease    05323 Rheumatoid arthritis     101704309 (Il1b)    05321 Inflammatory bowel disease     101704309 (Il1b)    05332 Graft-versus-host disease     101704309 (Il1b)   09164 Neurodegenerative disease    05010 Alzheimer disease     101704309 (Il1b)    05020 Prion disease     101704309 (Il1b)    05022 Pathways of neurodegeneration - multiple diseases     101704309 (Il1b)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101704309 (Il1b)    05418 Fluid shear stress and atherosclerosis     101704309 (Il1b)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     101704309 (Il1b)    04936 Alcoholic liver disease     101704309 (Il1b)    04932 Non-alcoholic fatty liver disease     101704309 (Il1b)    04933 AGE-RAGE signaling pathway in diabetic complications     101704309 (Il1b)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     101704309 (Il1b)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:hgl04052]     101704309 (Il1b)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101704309 (Il1b) Cytokines and neuropeptides [BR:hgl04052]  Cytokines   Interleukins    101704309 (Il1b) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101704309 (Il1b) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL1 IL1_propep Motif Other DBs NCBI-GeneID:  101704309 NCBI-ProteinID:  XP_004844587 UniProt:  A0A0P6J2Q6 LinkDB All DBs Position Un AA seq 267 aa AA seqDB search MAAVPEFSNEVTAYHSDENEMFFEVDGPKQMKHCFQDLDLCSLDEGIELQISHQHFKKSF QQVVSLIVAVEKLRKELVPCPWTFQDNDLRTFFPFIFEEEPIICDTWDDKYECDAPVLTR NCRLQDTQHKHLVLSDPCELKALHLNGENLNRQVVFSMSFVQGERRDDKIPVALGLKGKN LYLSCVMKDDKPVLQLESVDPKQYPKKKMEKRFVFNKIDGKSTVEFESAQYPNWYISTSQ AEHMPVFLGNNHGGQDITDFSMEFMSS NT seq 804 nt NT seq  +upstreamnt  +downstreamnt atggcagcagttcctgaattcagcaatgaagtgacagcttaccacagtgatgagaatgaa atgttctttgaggtcgatggccccaaacagatgaagcattgcttccaagacctggacctc tgctctctggatgagggcatcgagctacaaatctcccaccagcacttcaagaagagtttc cagcaggtggtgtcactcattgtggctgtggagaagctgaggaaggaactagttccttgc ccatggaccttccaggataatgacctgagaaccttctttcccttcatctttgaagaagaa cccatcatctgtgacacgtgggatgacaagtatgagtgtgatgcacccgtcctaacacgg aactgcagactccaggatacacaacataaacacctggtgttgtctgacccatgtgaactg aaagcccttcatctcaacggagagaatctgaaccggcaagtggtgttctccatgagcttt gtacaaggagaaagaagagatgacaaaatccctgttgctttgggcctcaagggaaagaat ctgtacctgtcctgtgtgatgaaagatgataaacctgtcctacagcttgagagtgtagac cccaaacagtacccaaagaagaagatggaaaagcgattcgtcttcaacaagatagatggc aaaagcacggtggaatttgagtctgctcagtaccccaactggtacatcagcacctctcaa gcagaacacatgcctgtcttcctgggaaataaccatggtggccaggacataactgacttc agcatggaattcatgtcttcctaa

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