KEGG   Heterocephalus glaber (naked mole-rat): 101704771
Entry
101704771         CDS       T02812                                 
Symbol
Ptgs2
Name
(RefSeq) prostaglandin-endoperoxide synthase 2
  KO
K11987  prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl00590  Arachidonic acid metabolism
hgl01100  Metabolic pathways
hgl04064  NF-kappa B signaling pathway
hgl04148  Efferocytosis
hgl04370  VEGF signaling pathway
hgl04625  C-type lectin receptor signaling pathway
hgl04657  IL-17 signaling pathway
hgl04668  TNF signaling pathway
hgl04723  Retrograde endocannabinoid signaling
hgl04726  Serotonergic synapse
hgl04913  Ovarian steroidogenesis
hgl04921  Oxytocin signaling pathway
hgl04923  Regulation of lipolysis in adipocytes
hgl05010  Alzheimer disease
hgl05022  Pathways of neurodegeneration - multiple diseases
hgl05140  Leishmaniasis
hgl05163  Human cytomegalovirus infection
hgl05165  Human papillomavirus infection
hgl05167  Kaposi sarcoma-associated herpesvirus infection
hgl05200  Pathways in cancer
hgl05204  Chemical carcinogenesis - DNA adducts
hgl05206  MicroRNAs in cancer
hgl05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    101704771 (Ptgs2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    101704771 (Ptgs2)
   04064 NF-kappa B signaling pathway
    101704771 (Ptgs2)
   04668 TNF signaling pathway
    101704771 (Ptgs2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101704771 (Ptgs2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101704771 (Ptgs2)
   04657 IL-17 signaling pathway
    101704771 (Ptgs2)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    101704771 (Ptgs2)
   04913 Ovarian steroidogenesis
    101704771 (Ptgs2)
   04921 Oxytocin signaling pathway
    101704771 (Ptgs2)
  09156 Nervous system
   04726 Serotonergic synapse
    101704771 (Ptgs2)
   04723 Retrograde endocannabinoid signaling
    101704771 (Ptgs2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101704771 (Ptgs2)
   05206 MicroRNAs in cancer
    101704771 (Ptgs2)
   05204 Chemical carcinogenesis - DNA adducts
    101704771 (Ptgs2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    101704771 (Ptgs2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101704771 (Ptgs2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101704771 (Ptgs2)
   05165 Human papillomavirus infection
    101704771 (Ptgs2)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    101704771 (Ptgs2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101704771 (Ptgs2)
   05022 Pathways of neurodegeneration - multiple diseases
    101704771 (Ptgs2)
Enzymes [BR:hgl01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.1  prostaglandin-endoperoxide synthase
     101704771 (Ptgs2)
SSDB
Motif
Pfam: An_peroxidase EGF hEGF
Other DBs
NCBI-GeneID: 101704771
NCBI-ProteinID: XP_004862837
UniProt: G5C6B9
LinkDB
Position
Un
AA seq 604 aa
MLARALLLCAALALCQAASPCCSNPCQNRGECLSVGFDRYQCDCTRTGFYGENCTTPEFL
TRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRNSIMRYVLTSRSHLIDSPPTYNSDY
GYRSWEAFSNLSYYTRVLPPVADDCPTPMGVKGKKELPDSNKVLEKVLLRRKFIPDPQGT
NMMFAFFAQHFTHQFFKSDPKRGPAFTTGLAHGVDLSHVYGETLDRQHKLRLFRDGKMKY
QIIDGEMYPPTVKDTQVQMIYPPHTPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCD
VLKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQ
NRIASEFNTLYHWHPLLPDTFQIHDQEYNFQQFLYNNSMLVEHGLTQFVESFTKQIAGRV
AGGRNVPLAVQKVAKASIDHSRNMKYQSLNEYRKHFLLKPYASFEDLTGEKEMAAELEAL
YGDIDAVELYPALLVEKPRPDAIFGETMVEMGAPFSLKGLMGNPICSPHYWKPSTFGGEV
GFKIINTASIQSLICTNVRGCPFTSFSIPDPELAKTVTINASASHSRLEDLNPTVLLKGH
SPEL
NT seq 1815 nt   +upstreamnt  +downstreamnt
atgctcgcccgcgccctgctgctctgcgcagccctggcgctctgccaggcagccagtcct
tgctgttccaatccgtgtcagaaccgaggagagtgtctcagcgtgggattcgaccgctac
cagtgcgactgtacccggacagggttctacggtgaaaactgcaccacgcctgaatttcta
acaagaataaaattactgctgaagcccactccaaacacagtgcactacatactcacccac
ttcaagggagtctggaacattgtcaacaacattcccttcctgcgaaattcaatcatgaga
tacgtgctgacgtccagatcacatttgattgacagcccaccaacttacaactcggattat
ggctacagaagctgggaagccttctctaacctttcctactacacccgagtcctccctcct
gtggcggatgactgccccactcccatgggtgtgaaagggaagaaggagcttcctgattca
aacaaggttctggagaaagttcttctgagaagaaagttcatccctgaccctcaaggcacg
aatatgatgtttgccttcttcgcccagcacttcacccatcagtttttcaagtcagatccg
aaacgcggaccagctttcaccacaggactggcccacggggtggacttaagtcatgtttat
ggtgaaactctggatagacagcataaactgcgccttttcagggatggaaaaatgaaatat
cagataattgatggagagatgtaccctcccacagtcaaagatacccaggtacagatgatc
tacccaccccacacccctgagcacctgcgcttcgccgtgggccaggaggtcttcggccta
gtgcccggtctgatgatgtatgccaccatctggctgcgggaacacaacagagtgtgcgac
gtgcttaaacaggagcatccggagtgggatgatgagcgtctgttccagacaagcaggcta
atactgataggagaaacaattaagattgtgattgaagactacgtacagcacttgagcggt
taccacttcaaactgaagtttgacccagagctgcttttcaaccaacaattccagtatcag
aaccgcattgcttctgagttcaacacactctaccactggcatccccttctgcctgacacc
tttcaaatccacgaccaggagtacaactttcaacagtttctctacaacaactctatgtta
gtggaacacggacttacccagtttgttgaatcattcaccaagcaaattgctggcagggtc
gctggtggcaggaatgttccacttgcagtacaaaaggtggcaaaggcttccattgaccac
agcagaaacatgaaataccaatctctgaatgagtaccgcaaacactttttgttgaagccc
tatgcctcatttgaagaccttacaggagagaaggaaatggctgcagagttggaagccctc
tacggtgacattgatgctgtggagctgtatcccgccctgctggtggaaaagcctcggcca
gacgctatcttcggtgagaccatggtggaaatgggagctccgttctccttgaaaggactc
atgggtaatcccatctgttccccacactactggaagccgagtacttttggaggagaagta
ggttttaagatcatcaacactgcttccatccagtctctcatctgcactaatgtgaggggt
tgtcctttcacatcgttcagtattccagatcctgagcttgccaaaacagtcaccattaac
gcaagtgcttcccactctagactggaggacctcaaccccacagtactgctaaaaggacat
tcaccggagctatag

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